FI69628C - Nytt foerfarande foer framstaellning av apovinkaminsyraestrar - Google Patents

Nytt foerfarande foer framstaellning av apovinkaminsyraestrar Download PDF

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Publication number
FI69628C
FI69628C FI812785A FI812785A FI69628C FI 69628 C FI69628 C FI 69628C FI 812785 A FI812785 A FI 812785A FI 812785 A FI812785 A FI 812785A FI 69628 C FI69628 C FI 69628C
Authority
FI
Finland
Prior art keywords
acid
process according
formula
reaction
organic solvent
Prior art date
Application number
FI812785A
Other languages
English (en)
Finnish (fi)
Other versions
FI812785L (fi
FI69628B (fi
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Janos Kreidl
Gyoergy Visky
Laszlo Czibula
Nee Kirjak Maria Farkas
Andras Nemes
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI812785L publication Critical patent/FI812785L/fi
Application granted granted Critical
Publication of FI69628B publication Critical patent/FI69628B/fi
Publication of FI69628C publication Critical patent/FI69628C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Claims (9)

1. Förfarande för framställning av racemiska eller optiskt aktiva apovinkaminsyraestrar med formeln I, - ------------- I | H ! Λ - N \ (I)
10. J R100C ^ ^ R2 1 2 van R och R oberoende av varandra är alkylgrupper med 15 1-6 kolatomer, kännetecknat därav, att en hyd- roxiamino-E-homoeburnan med formeln II - (II) ! I H°-™..... 25 r1°0c/ R2 1 2 van R och R är ovan definierade grupper, eller ett syra-additionssalt därav, omsättes med en organisk sulfonsyra i ett aprotiskt organiskt lösningsmedel.
2. Förfarande enligt patentkravet 1, känneteck-30 n a t därav, att man använder p-toluensulfonsyra som organisk sulfonsyra.
3. Förfarande enligt patentkravet 1, kännetecknat därav, att man använder etansulfonsyra eller bensen-sulfonsyra som organisk sulfonsyra. 35
4. Förfarande enligt nägot av de föregSende patent- kraven, kännetecknat därav, att man som aprotiskt organiskt lösningsmedel använder ett aromatiskt kolväte, som
FI812785A 1980-09-10 1981-09-08 Nytt foerfarande foer framstaellning av apovinkaminsyraestrar FI69628C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU220880 1980-09-10
HU802208A HU183207B (en) 1980-09-10 1980-09-10 Process for preparing apovincaminic acid esters

Publications (3)

Publication Number Publication Date
FI812785L FI812785L (fi) 1982-03-11
FI69628B FI69628B (fi) 1985-11-29
FI69628C true FI69628C (fi) 1986-03-10

Family

ID=10958296

Family Applications (1)

Application Number Title Priority Date Filing Date
FI812785A FI69628C (fi) 1980-09-10 1981-09-08 Nytt foerfarande foer framstaellning av apovinkaminsyraestrar

Country Status (25)

Country Link
JP (1) JPS5780384A (sv)
AT (1) AT382616B (sv)
AU (1) AU544436B2 (sv)
BE (1) BE890274A (sv)
CA (1) CA1162543A (sv)
CH (1) CH646167A5 (sv)
DD (1) DD201680A5 (sv)
DE (1) DE3135728C2 (sv)
DK (1) DK151020C (sv)
ES (1) ES8206522A1 (sv)
FI (1) FI69628C (sv)
FR (1) FR2489824B1 (sv)
GB (1) GB2086886B (sv)
GR (1) GR75030B (sv)
HU (1) HU183207B (sv)
IL (1) IL63720A0 (sv)
IT (1) IT1146707B (sv)
NL (1) NL8104044A (sv)
NO (1) NO813067L (sv)
NZ (1) NZ198318A (sv)
PT (1) PT73644B (sv)
SE (1) SE443141B (sv)
SU (1) SU1114336A3 (sv)
YU (1) YU41987B (sv)
ZA (1) ZA816100B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052449B1 (es) * 1992-12-22 1995-02-16 Covex Sa Nuevo procedimiento para la preparacion del apovincaminato de etilo.
DE60233721D1 (de) 2001-03-15 2009-10-29 Honda Access Kk Struktur für die montage einer satteltasche an einem motorrad

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2389625B1 (sv) * 1977-05-06 1980-04-18 Roussel Uclaf
HU179292B (en) * 1978-12-01 1982-09-28 Richter Gedeon Vegyeszet Process for preparing ester derivatives of apovincaminic acid
HU181495B (en) * 1979-05-31 1983-07-28 Richter Gedeon Vegyeszet Process for producing hydroxy-imino-eburnane derivatives

Also Published As

Publication number Publication date
ATA376081A (de) 1986-08-15
HU183207B (en) 1984-04-28
FR2489824A1 (fr) 1982-03-12
GB2086886A (en) 1982-05-19
CA1162543A (en) 1984-02-21
DK396881A (da) 1982-03-11
DE3135728A1 (de) 1982-04-01
ZA816100B (en) 1983-03-30
YU41987B (en) 1988-04-30
AT382616B (de) 1987-03-25
SE8105338L (sv) 1982-03-11
ES505325A0 (es) 1982-08-16
SE443141B (sv) 1986-02-17
IL63720A0 (en) 1981-12-31
FI812785L (fi) 1982-03-11
GR75030B (sv) 1984-07-12
IT8168172A0 (it) 1981-09-04
DK151020B (da) 1987-10-12
DK151020C (da) 1988-02-29
BE890274A (fr) 1982-01-04
PT73644B (en) 1983-10-20
NO813067L (no) 1982-03-11
AU7509281A (en) 1982-03-18
AU544436B2 (en) 1985-05-30
JPS6259106B2 (sv) 1987-12-09
FI69628B (fi) 1985-11-29
ES8206522A1 (es) 1982-08-16
GB2086886B (en) 1984-06-13
PT73644A (en) 1981-10-01
NL8104044A (nl) 1982-04-01
IT1146707B (it) 1986-11-19
FR2489824B1 (fr) 1985-10-11
DD201680A5 (de) 1983-08-03
JPS5780384A (en) 1982-05-19
DE3135728C2 (de) 1994-09-22
NZ198318A (en) 1983-06-14
CH646167A5 (de) 1984-11-15
SU1114336A3 (ru) 1984-09-15
YU218181A (en) 1984-02-29

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYéSZETI GYAR R.T.