FI69449C - Foerfarande foer framstaellning av farmakologiskt verksamma glseroldiestrar - Google Patents

Foerfarande foer framstaellning av farmakologiskt verksamma glseroldiestrar Download PDF

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Publication number
FI69449C
FI69449C FI800683A FI800683A FI69449C FI 69449 C FI69449 C FI 69449C FI 800683 A FI800683 A FI 800683A FI 800683 A FI800683 A FI 800683A FI 69449 C FI69449 C FI 69449C
Authority
FI
Finland
Prior art keywords
mixture
glyceryl
bis
propyl acetate
acid
Prior art date
Application number
FI800683A
Other languages
English (en)
Finnish (fi)
Other versions
FI800683A (fi
FI69449B (fi
Inventor
Michel Chignac
Fernand Jammot
Pierre Eymard
Claude Grain
Charles Pigerol
Bernard Ferrandes
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI800683A publication Critical patent/FI800683A/fi
Application granted granted Critical
Publication of FI69449B publication Critical patent/FI69449B/fi
Publication of FI69449C publication Critical patent/FI69449C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI800683A 1979-03-06 1980-03-05 Foerfarande foer framstaellning av farmakologiskt verksamma glseroldiestrar FI69449C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7907932 1979-03-06
GB7907932 1979-03-06

Publications (3)

Publication Number Publication Date
FI800683A FI800683A (fi) 1980-09-07
FI69449B FI69449B (fi) 1985-10-31
FI69449C true FI69449C (fi) 1986-02-10

Family

ID=10503667

Family Applications (1)

Application Number Title Priority Date Filing Date
FI800683A FI69449C (fi) 1979-03-06 1980-03-05 Foerfarande foer framstaellning av farmakologiskt verksamma glseroldiestrar

Country Status (29)

Country Link
US (1) US4423071A (xx)
EP (1) EP0018342B1 (xx)
JP (1) JPS55141436A (xx)
AR (1) AR224394A1 (xx)
AU (1) AU534007B2 (xx)
CA (1) CA1162928A (xx)
CS (1) CS216526B2 (xx)
CY (1) CY1209A (xx)
DD (2) DD151931A5 (xx)
DE (1) DE3061960D1 (xx)
DK (1) DK93880A (xx)
ES (1) ES489250A0 (xx)
FI (1) FI69449C (xx)
GR (1) GR70703B (xx)
HK (1) HK22384A (xx)
HU (2) HU188840B (xx)
IE (1) IE49539B1 (xx)
IL (1) IL59407A (xx)
IN (1) IN152492B (xx)
MY (1) MY8500075A (xx)
NO (1) NO152899C (xx)
NZ (1) NZ192944A (xx)
OA (1) OA06568A (xx)
PL (1) PL124023B1 (xx)
PT (1) PT70904A (xx)
SG (1) SG61583G (xx)
SU (3) SU1195901A3 (xx)
YU (2) YU41699B (xx)
ZA (1) ZA801081B (xx)

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FR2627487B1 (fr) * 1988-02-19 1991-03-29 Martin Laboratoires Nouveau derive de l'acide valproique, procede de preparation de ce compose ainsi que medicament antiepileptique le contenant
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JPH01299222A (ja) * 1988-05-26 1989-12-04 Otsuka Pharmaceut Factory Inc 抗腫瘍剤
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CA2060685A1 (en) * 1991-03-04 1992-09-05 Mahmood Sabahi Ether-ester lubricant
JP3828147B2 (ja) * 1994-04-19 2006-10-04 株式会社カネカ トリアゾール誘導体の製造法
DK0823897T3 (da) * 1995-05-01 2004-12-06 Scarista Ltd Nicotinsyreestere og farmaceutiske præparater indeholdende disse
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
USRE40546E1 (en) * 1996-05-01 2008-10-21 Scarista, Ltd. 1,3-Propane diol esters and ethers and methods for their use in drug delivery
DE19534519A1 (de) * 1995-09-05 1997-07-10 Desitin Arzneimittel Gmbh Zucker oder Zuckeralkohole zur Verwendung als Antiepileptikum
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
JP4526741B2 (ja) * 2001-07-18 2010-08-18 花王株式会社 エーテルカルボキシレートモノグリセリド
FR2828487B1 (fr) * 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
CA2526475A1 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
ES2594867T3 (es) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Unidad de calentamiento para usar en un dispositivo de administración de fármaco
SE532942C2 (sv) * 2008-10-27 2010-05-18 Perstorp Specialty Chem Ab Smörjmedelsbasmassa med låg droppunkt
EP2354130A1 (en) * 2010-02-02 2011-08-10 Momentive Specialty Chemicals Research Belgium Manufacture of an epoxyethyl carboxylate or glycidyl carboxylate
WO2013072481A1 (de) * 2011-11-17 2013-05-23 Basf Coatings Gmbh Glyceroldiester, verfahren zu deren herstellung und deren verwendung in beschichtungsmitteln
US9744542B2 (en) 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
ES2784914T3 (es) 2015-05-20 2020-10-02 Apeel Tech Inc Composiciones de extractos de plantas y métodos de preparación de las mismas
JP7049245B2 (ja) 2015-09-16 2022-04-06 アピール テクノロジー，インコーポレイテッド 分子コーティングのための前駆体化合物
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CN109068627B (zh) 2016-01-26 2022-03-18 阿比尔技术公司 用于制备和保存消毒产品的方法
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Also Published As

Publication number Publication date
ES8103015A1 (es) 1981-02-16
AU534007B2 (en) 1983-12-22
HU188840B (en) 1986-05-28
ES489250A0 (es) 1981-02-16
HU183072B (en) 1984-04-28
JPS55141436A (en) 1980-11-05
YU41699B (en) 1987-12-31
IE49539B1 (en) 1985-10-30
FI800683A (fi) 1980-09-07
DD158773A5 (de) 1983-02-02
US4423071A (en) 1983-12-27
IL59407A0 (en) 1980-05-30
EP0018342A1 (fr) 1980-10-29
DD151931A5 (de) 1981-11-11
IN152492B (xx) 1984-01-28
PL222446A1 (xx) 1981-01-30
AR224394A1 (es) 1981-11-30
AU5587280A (en) 1980-09-11
NO800626L (no) 1980-09-08
NO152899C (no) 1985-12-11
PT70904A (en) 1980-04-01
EP0018342B1 (fr) 1983-02-16
SU1195901A3 (ru) 1985-11-30
SU1052507A1 (ru) 1983-11-07
ZA801081B (en) 1981-03-25
IE800445L (en) 1980-09-06
NO152899B (no) 1985-09-02
PL124023B1 (en) 1982-12-31
MY8500075A (en) 1985-12-31
JPS6315256B2 (xx) 1988-04-04
CS216526B2 (en) 1982-11-26
CA1162928A (en) 1984-02-28
YU292382A (en) 1983-09-30
DK93880A (da) 1980-09-07
NZ192944A (en) 1984-07-06
FI69449B (fi) 1985-10-31
HK22384A (en) 1984-03-23
YU42064B (en) 1988-04-30
IL59407A (en) 1983-12-30
SU1225481A3 (ru) 1986-04-15
SG61583G (en) 1985-02-15
GR70703B (xx) 1983-01-04
YU61580A (en) 1983-04-30
OA06568A (fr) 1981-08-31
DE3061960D1 (en) 1983-03-24
CY1209A (en) 1983-12-31

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Owner name: SANOFI