FI64366C - Analogifoerfarande foer framstaellning av antihypertensiva kinazolinderivat - Google Patents

Analogifoerfarande foer framstaellning av antihypertensiva kinazolinderivat Download PDF

Info

Publication number
FI64366C
FI64366C FI783347A FI783347A FI64366C FI 64366 C FI64366 C FI 64366C FI 783347 A FI783347 A FI 783347A FI 783347 A FI783347 A FI 783347A FI 64366 C FI64366 C FI 64366C
Authority
FI
Finland
Prior art keywords
formula
benzodioxane
quinazoline
mixture
group
Prior art date
Application number
FI783347A
Other languages
English (en)
Finnish (fi)
Other versions
FI783347A (fi
FI64366B (fi
Inventor
Simon Fraser Campbell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI783347A publication Critical patent/FI783347A/fi
Application granted granted Critical
Publication of FI64366B publication Critical patent/FI64366B/fi
Publication of FI64366C publication Critical patent/FI64366C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI783347A 1977-11-05 1978-11-02 Analogifoerfarande foer framstaellning av antihypertensiva kinazolinderivat FI64366C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05
GB4612877 1977-11-05

Publications (3)

Publication Number Publication Date
FI783347A FI783347A (fi) 1979-05-06
FI64366B FI64366B (fi) 1983-07-29
FI64366C true FI64366C (fi) 1983-11-10

Family

ID=10439957

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783347A FI64366C (fi) 1977-11-05 1978-11-02 Analogifoerfarande foer framstaellning av antihypertensiva kinazolinderivat

Country Status (36)

Country Link
JP (1) JPS5498792A (da)
AR (2) AR219562A1 (da)
AT (1) AT365186B (da)
AU (1) AU509329B2 (da)
BE (1) BE871771A (da)
CA (1) CA1088059A (da)
CH (1) CH643255A5 (da)
CS (2) CS207671B2 (da)
DD (1) DD139850A5 (da)
DE (1) DE2847623C2 (da)
DK (1) DK154082C (da)
EG (1) EG13594A (da)
ES (2) ES474805A1 (da)
FI (1) FI64366C (da)
FR (1) FR2407929A1 (da)
GR (1) GR81514B (da)
HK (1) HK94284A (da)
HU (1) HU176306B (da)
IE (1) IE47888B1 (da)
IL (1) IL55857A (da)
IN (1) IN148828B (da)
IT (1) IT1100919B (da)
KE (1) KE3350A (da)
LU (2) LU80470A1 (da)
MY (1) MY8500286A (da)
NL (2) NL174549C (da)
NO (1) NO150158C (da)
NZ (1) NZ188813A (da)
PH (1) PH13966A (da)
PL (2) PL119586B1 (da)
PT (1) PT68735A (da)
SE (1) SE437518B (da)
SU (1) SU816403A3 (da)
UA (1) UA8324A1 (da)
YU (2) YU40204B (da)
ZA (1) ZA786184B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002617A1 (en) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1986002644A1 (en) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1985004658A1 (en) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepine derivatives and their preparation
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
PT849266E (pt) * 1996-12-20 2007-03-30 Heumann Pcs Gmbh Nova forma polimorfa de mesilato de doxazosina (forma iii)
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
PL210681A1 (da) 1979-11-05
IT7829434A0 (it) 1978-11-03
YU38683A (en) 1983-06-30
IE782179L (en) 1979-05-05
FI783347A (fi) 1979-05-06
ATA784378A (de) 1981-05-15
HK94284A (en) 1984-12-07
EG13594A (en) 1982-03-31
ES480121A0 (es) 1980-07-16
AR219562A1 (es) 1980-08-29
PT68735A (en) 1978-12-01
DD139850A5 (de) 1980-01-23
NL174549C (nl) 1984-07-02
LU88331I2 (fr) 1994-05-04
CS207671B2 (en) 1981-08-31
NL174549B (nl) 1984-02-01
DK154082C (da) 1989-02-27
NL930062I2 (nl) 1993-11-16
IL55857A0 (en) 1979-01-31
SE7811382L (sv) 1979-05-06
NO150158C (no) 1984-08-29
NO783705L (no) 1979-05-08
NZ188813A (en) 1980-10-08
LU80470A1 (fr) 1980-06-05
KE3350A (en) 1983-12-16
BE871771A (fr) 1979-05-03
ES474805A1 (es) 1980-01-16
DK154082B (da) 1988-10-10
CS354491A3 (en) 1992-06-17
ZA786184B (en) 1979-10-31
ES8308559A1 (es) 1980-07-16
CA1088059A (en) 1980-10-21
HU176306B (en) 1981-01-28
IE47888B1 (en) 1984-07-11
UA8324A1 (uk) 1996-03-29
NL7810909A (nl) 1979-05-08
FR2407929A1 (fr) 1979-06-01
SU816403A3 (ru) 1981-03-23
DE2847623C2 (de) 1983-06-01
PL119419B1 (en) 1981-12-31
PH13966A (en) 1980-11-12
SE437518B (sv) 1985-03-04
YU255378A (en) 1983-06-30
YU40419B (en) 1985-12-31
IL55857A (en) 1982-07-30
DK428678A (da) 1979-05-06
IT1100919B (it) 1985-09-28
IN148828B (da) 1981-06-27
AU509329B2 (en) 1980-05-08
PL119586B1 (en) 1982-01-30
YU40204B (en) 1985-08-31
MY8500286A (en) 1985-12-31
AT365186B (de) 1981-12-28
CH643255A5 (en) 1984-05-30
AR223015A1 (es) 1981-07-15
FI64366B (fi) 1983-07-29
GR81514B (da) 1984-12-11
DE2847623A1 (de) 1979-05-23
JPS5625233B2 (da) 1981-06-11
JPS5498792A (en) 1979-08-03
FR2407929B1 (da) 1981-02-27
NL930062I1 (nl) 1993-09-01
NO150158B (no) 1984-05-21
AU4132278A (en) 1979-05-17

Similar Documents

Publication Publication Date Title
JP7416365B2 (ja) アポトーシス誘発剤
US4188390A (en) Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
RU2155187C2 (ru) Производные индола, их таутомеры, смеси их изомеров или отдельные изомеры и фармацевтически приемлемые соли, фармацевтическая композиция с антиопухолевой или ингибирующей протеин-тирозинкиназу активностью и способ торможения зависящего от протеин-тирозинкиназы заболевания или борьбы с аберрантным ростом клеток млекопитающего или человека.
EP0850235B1 (fr) Derives de quinolein-2(1h)-one comme antagonistes de la serotonine
DE3888821T2 (de) Tricyclische Verbindungen.
US20060293304A1 (en) Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
JPH09506363A (ja) 4,6−ジアニリノ−ピリミジン誘導体、それらの製造およびチロシンキナーゼ阻害剤としてのそれらの用途
FI64366C (fi) Analogifoerfarande foer framstaellning av antihypertensiva kinazolinderivat
JPS6131104B2 (da)
JP2002105081A (ja) 新規チオフェンニ環化合物
WO1999027965A1 (fr) Agents anti-hyperlipemiques
US5328910A (en) Sino-atrial node modulating pyrrolopyrimidines
DE69109132T2 (de) Indanderivate.
US4423056A (en) 5(Aminomethyl)-4,5,6,7-tetrahydro[d]thiazole containing compositions for and medical use in treating circulatory insufficiencies
EP0458160A2 (en) Substituted diphenylmethane derivatives as analgesic or anti-inflammatory agents
US6407112B1 (en) Optically active tetrahydrobenzindole derivative
JP2959598B2 (ja) 光学活性なチエノトリアゾロジアゼピン化合物
JPH03264579A (ja) ピリミジン誘導体
JP3465827B2 (ja) アザインドール誘導体およびこれを有効成分とする抗潰瘍薬
PT89490B (pt) Processo para a preparacao de benzotienopiridinas e de composicoes farmaceuticas contendo-as
DE69314022T2 (de) Derivate von 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranen
GB2171997A (en) 4-Amino-6,7-dimethoxy-2-Piperazin-1-ylquinazoline derivatives
US4929616A (en) Novel basic-substituted 5-halo-thienoisothiazol-3(2H)-one 1,1-dioxides, a process for the preparation thereof, and pharmaceutical preparations containing these compounds
EA014236B1 (ru) Новые пиперазиновые производные диалкилоксиндолов
JPS6333378A (ja) ピリド〔1,8〕ナフチリジノン、その製造方法及びそれらの化合物を含有する製剤

Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: PFIZER CORPORATION