FI64149C - Foerfarande foer framstaellning av nya antihypertensiva pyridazinylhydrazoner - Google Patents

Foerfarande foer framstaellning av nya antihypertensiva pyridazinylhydrazoner Download PDF

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Publication number
FI64149C
FI64149C FI781886A FI781886A FI64149C FI 64149 C FI64149 C FI 64149C FI 781886 A FI781886 A FI 781886A FI 781886 A FI781886 A FI 781886A FI 64149 C FI64149 C FI 64149C
Authority
FI
Finland
Prior art keywords
alkyl
general formula
hydrogen
phenyl
chloro
Prior art date
Application number
FI781886A
Other languages
English (en)
Finnish (fi)
Other versions
FI781886A (fi
FI64149B (fi
Inventor
Geza Szilagyi
Endre Kasztreiner
Judit Kosary
Peter Matyus
Zsuzsa Huszti
Gyoergy Cseh
Agnes Kennessey
Laszlo Tardos
Edit Kosa
Laszlo Jaszlits
Sandor Elek
Istvan Elekes
Istvan Polgari
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI781886A publication Critical patent/FI781886A/fi
Publication of FI64149B publication Critical patent/FI64149B/fi
Application granted granted Critical
Publication of FI64149C publication Critical patent/FI64149C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI781886A 1977-06-13 1978-06-13 Foerfarande foer framstaellning av nya antihypertensiva pyridazinylhydrazoner FI64149C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUGO001372 1977-06-13
HU77GO1372A HU176972B (hu) 1977-06-13 1977-06-13 Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona

Publications (3)

Publication Number Publication Date
FI781886A FI781886A (fi) 1978-12-14
FI64149B FI64149B (fi) 1983-06-30
FI64149C true FI64149C (fi) 1983-10-10

Family

ID=10996833

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781886A FI64149C (fi) 1977-06-13 1978-06-13 Foerfarande foer framstaellning av nya antihypertensiva pyridazinylhydrazoner

Country Status (24)

Country Link
US (2) US4259328A (pl)
JP (2) JPS6019754B2 (pl)
AT (1) AT359075B (pl)
AU (1) AU521639B2 (pl)
BE (1) BE868027A (pl)
BG (2) BG33283A3 (pl)
CA (1) CA1077937A (pl)
CH (1) CH638189A5 (pl)
CS (1) CS244653B2 (pl)
DD (1) DD138901A5 (pl)
DE (1) DE2825861A1 (pl)
DK (1) DK148683C (pl)
ES (1) ES470751A1 (pl)
FI (1) FI64149C (pl)
FR (1) FR2394535A1 (pl)
GB (1) GB2000125B (pl)
HU (1) HU176972B (pl)
IL (1) IL54899A (pl)
NL (1) NL7806381A (pl)
NO (1) NO154392C (pl)
PL (2) PL113210B1 (pl)
SE (1) SE445216B (pl)
SU (3) SU867300A3 (pl)
YU (1) YU40710B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470229A (en) * 1977-11-11 1979-06-05 Toray Ind Inc Separation of 8c aromatic hydrocarbons
HU178552B (en) * 1978-07-14 1982-05-28 Gyogyszerkutato Intezet Process for producing new blood pressure lowering composition of increased activity
HU179191B (en) * 1979-05-07 1982-09-28 Gyogyszerkutato Intezet New process for preparing 6-/substituted amino/-3-pyridazinyl-hydrazines and salts thereof
FR2668151A1 (fr) * 1990-10-23 1992-04-24 Rhone Poulenc Agrochimie Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
US5417208A (en) * 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
EP1491532B1 (en) * 1997-10-27 2010-12-15 NeuroSearch A/S Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetyloholine receptors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1157642A (en) * 1965-10-08 1969-07-09 Lepetit Spa 3-Hydrazino-6-Amino-Pyridazines
US3528969A (en) * 1967-11-30 1970-09-15 Sandoz Ag Benzylidene hydrazones
US3642792A (en) * 1968-02-26 1972-02-15 Lepetit Spa Pyridazine derivatives
US3706744A (en) * 1970-11-16 1972-12-19 Sandoz Ag Hydrazone derivatives of 3-substituted amino-6-hydrazino pyridazines
US3717632A (en) * 1971-01-29 1973-02-20 Sandoz Ag Substituted-3-hydrazino pyridazines
US3717635A (en) * 1971-02-22 1973-02-20 Sandoz Ag Hydrazino and substituted hydrazino pyridazine-n-oxides
DE2202744A1 (de) * 1972-01-21 1973-07-26 Boehringer Mannheim Gmbh Nitrofuryl-triazolo eckige klammer auf 4,3-b eckige klammer zu-pyridazin-amide
US3978057A (en) * 1972-04-05 1976-08-31 Sandoz, Inc. Substituted amino-hydrazinopyridazines
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.
FR2306697A1 (fr) * 1975-04-10 1976-11-05 Sogeras Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants

Also Published As

Publication number Publication date
DD138901A5 (de) 1979-11-28
SE445216B (sv) 1986-06-09
PL113210B1 (en) 1980-11-29
BG33284A3 (en) 1983-01-14
FI781886A (fi) 1978-12-14
NO782042L (no) 1978-12-14
PL113062B1 (en) 1980-11-29
JPS5762267A (en) 1982-04-15
ES470751A1 (es) 1979-02-01
PL207592A1 (pl) 1979-05-07
JPS5416486A (en) 1979-02-07
FR2394535B1 (pl) 1982-06-25
IL54899A (en) 1982-05-31
US4308386A (en) 1981-12-29
JPS6019754B2 (ja) 1985-05-17
GB2000125B (en) 1982-05-06
FI64149B (fi) 1983-06-30
CS244653B2 (en) 1986-08-14
CA1077937A (en) 1980-05-20
NL7806381A (nl) 1978-12-15
NO154392B (no) 1986-06-02
CH638189A5 (de) 1983-09-15
HU176972B (hu) 1981-06-28
DE2825861A1 (de) 1979-01-04
SU867300A3 (ru) 1981-09-23
DE2825861C2 (pl) 1989-10-05
DK148683C (da) 1986-02-24
FR2394535A1 (fr) 1979-01-12
DK148683B (da) 1985-09-02
NO154392C (no) 1986-09-10
YU140178A (en) 1983-01-21
BE868027A (fr) 1978-12-12
YU40710B (en) 1986-04-30
SU890977A3 (ru) 1981-12-15
ATA424078A (de) 1980-03-15
GB2000125A (en) 1979-01-04
DK262978A (da) 1978-12-14
SE7806577L (sv) 1978-12-14
IL54899A0 (en) 1978-08-31
SU936811A3 (ru) 1982-06-15
US4259328A (en) 1981-03-31
AU3706678A (en) 1979-12-20
BG33283A3 (en) 1983-01-14
AT359075B (de) 1980-10-27
JPS6021983B2 (ja) 1985-05-30
AU521639B2 (en) 1982-04-22

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYOER R.T.