ES470751A1 - Procedimiento de preparacion de nuevas piridazinilhidrazonasy de sus sales farmaceuticamente aceptables - Google Patents

Procedimiento de preparacion de nuevas piridazinilhidrazonasy de sus sales farmaceuticamente aceptables

Info

Publication number
ES470751A1
ES470751A1 ES470751A ES470751A ES470751A1 ES 470751 A1 ES470751 A1 ES 470751A1 ES 470751 A ES470751 A ES 470751A ES 470751 A ES470751 A ES 470751A ES 470751 A1 ES470751 A1 ES 470751A1
Authority
ES
Spain
Prior art keywords
pyridazinylhydrazones
morpholino
formula
image
carbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470751A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES470751A1 publication Critical patent/ES470751A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento de preparación de nuevas piridazinilhidrazonas de fórmula general I: **(Fórmula)** en la que R1 representa hidrógeno, cloro, alquilo de 1 a 4 átomos de carbono, metoxilo, hidroxilo, carbamoílo o ciano, R2 representa hidrógeno, cloro o el grupo NR7R8, en el que R7 y R8 representan independientemente hidrógeno, alquilo de 1 a 5 átomos de carbono o hidroxialquilo de 2 a 4 átomos de carbono, o bien R7 y R8 junto con el átomo de nitrógeno al que están fijados, pueden formar un anillo morfolino, piperidino, piperazino o N-metilpiperazino.
ES470751A 1977-06-13 1978-06-13 Procedimiento de preparacion de nuevas piridazinilhidrazonasy de sus sales farmaceuticamente aceptables Expired ES470751A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1372A HU176972B (hu) 1977-06-13 1977-06-13 Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona

Publications (1)

Publication Number Publication Date
ES470751A1 true ES470751A1 (es) 1979-02-01

Family

ID=10996833

Family Applications (1)

Application Number Title Priority Date Filing Date
ES470751A Expired ES470751A1 (es) 1977-06-13 1978-06-13 Procedimiento de preparacion de nuevas piridazinilhidrazonasy de sus sales farmaceuticamente aceptables

Country Status (24)

Country Link
US (2) US4259328A (es)
JP (2) JPS6019754B2 (es)
AT (1) AT359075B (es)
AU (1) AU521639B2 (es)
BE (1) BE868027A (es)
BG (2) BG33284A3 (es)
CA (1) CA1077937A (es)
CH (1) CH638189A5 (es)
CS (1) CS244653B2 (es)
DD (1) DD138901A5 (es)
DE (1) DE2825861A1 (es)
DK (1) DK148683C (es)
ES (1) ES470751A1 (es)
FI (1) FI64149C (es)
FR (1) FR2394535A1 (es)
GB (1) GB2000125B (es)
HU (1) HU176972B (es)
IL (1) IL54899A (es)
NL (1) NL7806381A (es)
NO (1) NO154392C (es)
PL (2) PL113210B1 (es)
SE (1) SE445216B (es)
SU (3) SU867300A3 (es)
YU (1) YU40710B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470229A (en) * 1977-11-11 1979-06-05 Toray Ind Inc Separation of 8c aromatic hydrocarbons
HU178552B (en) * 1978-07-14 1982-05-28 Gyogyszerkutato Intezet Process for producing new blood pressure lowering composition of increased activity
HU179191B (en) * 1979-05-07 1982-09-28 Gyogyszerkutato Intezet New process for preparing 6-/substituted amino/-3-pyridazinyl-hydrazines and salts thereof
FR2668151A1 (fr) * 1990-10-23 1992-04-24 Rhone Poulenc Agrochimie Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
US5417208A (en) * 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
BR9813279B1 (pt) * 1997-10-27 2010-11-16 derivado de homopiperazina, composição farmacêutica, e, uso do derivado de homopiperazina.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1157642A (en) * 1965-10-08 1969-07-09 Lepetit Spa 3-Hydrazino-6-Amino-Pyridazines
US3528969A (en) * 1967-11-30 1970-09-15 Sandoz Ag Benzylidene hydrazones
US3642792A (en) * 1968-02-26 1972-02-15 Lepetit Spa Pyridazine derivatives
US3706744A (en) * 1970-11-16 1972-12-19 Sandoz Ag Hydrazone derivatives of 3-substituted amino-6-hydrazino pyridazines
US3717632A (en) * 1971-01-29 1973-02-20 Sandoz Ag Substituted-3-hydrazino pyridazines
US3717635A (en) * 1971-02-22 1973-02-20 Sandoz Ag Hydrazino and substituted hydrazino pyridazine-n-oxides
DE2202744A1 (de) * 1972-01-21 1973-07-26 Boehringer Mannheim Gmbh Nitrofuryl-triazolo eckige klammer auf 4,3-b eckige klammer zu-pyridazin-amide
US3978057A (en) * 1972-04-05 1976-08-31 Sandoz, Inc. Substituted amino-hydrazinopyridazines
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.
FR2306697A1 (fr) * 1975-04-10 1976-11-05 Sogeras Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants

Also Published As

Publication number Publication date
GB2000125B (en) 1982-05-06
YU140178A (en) 1983-01-21
PL207592A1 (pl) 1979-05-07
CH638189A5 (de) 1983-09-15
FI64149B (fi) 1983-06-30
NO154392C (no) 1986-09-10
JPS6019754B2 (ja) 1985-05-17
US4308386A (en) 1981-12-29
JPS6021983B2 (ja) 1985-05-30
PL113062B1 (en) 1980-11-29
SE445216B (sv) 1986-06-09
ATA424078A (de) 1980-03-15
HU176972B (hu) 1981-06-28
BG33283A3 (en) 1983-01-14
FR2394535A1 (fr) 1979-01-12
JPS5416486A (en) 1979-02-07
GB2000125A (en) 1979-01-04
NO782042L (no) 1978-12-14
AU521639B2 (en) 1982-04-22
DK148683B (da) 1985-09-02
SE7806577L (sv) 1978-12-14
SU936811A3 (ru) 1982-06-15
FI781886A (fi) 1978-12-14
DE2825861C2 (es) 1989-10-05
FI64149C (fi) 1983-10-10
DD138901A5 (de) 1979-11-28
JPS5762267A (en) 1982-04-15
DE2825861A1 (de) 1979-01-04
US4259328A (en) 1981-03-31
NO154392B (no) 1986-06-02
BE868027A (fr) 1978-12-12
SU867300A3 (ru) 1981-09-23
AT359075B (de) 1980-10-27
NL7806381A (nl) 1978-12-15
DK148683C (da) 1986-02-24
CA1077937A (en) 1980-05-20
IL54899A (en) 1982-05-31
DK262978A (da) 1978-12-14
YU40710B (en) 1986-04-30
IL54899A0 (en) 1978-08-31
CS244653B2 (en) 1986-08-14
PL113210B1 (en) 1980-11-29
FR2394535B1 (es) 1982-06-25
AU3706678A (en) 1979-12-20
SU890977A3 (ru) 1981-12-15
BG33284A3 (en) 1983-01-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990405