FI63393C - Foerfarande foer framstaellning av farmakologiskt vaerdefulla isokinolin-1(2h)-oner eller 1,6-naftyridin-5(6h)oner - Google Patents

Foerfarande foer framstaellning av farmakologiskt vaerdefulla isokinolin-1(2h)-oner eller 1,6-naftyridin-5(6h)oner Download PDF

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Publication number
FI63393C
FI63393C FI773717A FI773717A FI63393C FI 63393 C FI63393 C FI 63393C FI 773717 A FI773717 A FI 773717A FI 773717 A FI773717 A FI 773717A FI 63393 C FI63393 C FI 63393C
Authority
FI
Finland
Prior art keywords
group
phenyl
methyl
carbon atoms
methoxy
Prior art date
Application number
FI773717A
Other languages
English (en)
Finnish (fi)
Other versions
FI63393B (fi
FI773717A (fi
Inventor
Joachim Heider
Volkhard Austel
Wolfgang Eberlein
Rudolf Kadatz
Juergen Daemmgen
Walter Kobinger
Christian Lillie
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI773717A publication Critical patent/FI773717A/fi
Publication of FI63393B publication Critical patent/FI63393B/fi
Application granted granted Critical
Publication of FI63393C publication Critical patent/FI63393C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI773717A 1977-01-22 1977-12-09 Foerfarande foer framstaellning av farmakologiskt vaerdefulla isokinolin-1(2h)-oner eller 1,6-naftyridin-5(6h)oner FI63393C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2702600 1977-01-22
DE19772702600 DE2702600A1 (de) 1977-01-22 1977-01-22 Neue aminoalkoxyphenyl-derivate

Publications (3)

Publication Number Publication Date
FI773717A FI773717A (fi) 1978-07-23
FI63393B FI63393B (fi) 1983-02-28
FI63393C true FI63393C (fi) 1983-06-10

Family

ID=5999300

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773717A FI63393C (fi) 1977-01-22 1977-12-09 Foerfarande foer framstaellning av farmakologiskt vaerdefulla isokinolin-1(2h)-oner eller 1,6-naftyridin-5(6h)oner

Country Status (36)

Country Link
US (1) US4154837A (xx)
JP (1) JPS5392786A (xx)
AT (1) AT361480B (xx)
AU (1) AU516692B2 (xx)
BE (1) BE863160A (xx)
BG (1) BG28573A3 (xx)
CA (1) CA1106846A (xx)
CH (1) CH640227A5 (xx)
CS (1) CS195653B2 (xx)
DD (1) DD135283A5 (xx)
DE (1) DE2702600A1 (xx)
DK (1) DK149847C (xx)
ES (1) ES465455A1 (xx)
FI (1) FI63393C (xx)
FR (1) FR2378014A1 (xx)
GB (1) GB1568021A (xx)
GR (1) GR64093B (xx)
HK (1) HK60083A (xx)
HU (1) HU176895B (xx)
IE (1) IE46376B1 (xx)
IL (1) IL53857A (xx)
IT (1) IT1102816B (xx)
LU (1) LU78919A1 (xx)
MY (1) MY8400275A (xx)
NL (1) NL7800717A (xx)
NO (1) NO149502C (xx)
NZ (1) NZ186287A (xx)
PH (1) PH13911A (xx)
PL (1) PL112130B1 (xx)
PT (1) PT67561B (xx)
RO (1) RO72911A (xx)
SE (1) SE444433B (xx)
SG (1) SG42883G (xx)
SU (1) SU677654A3 (xx)
YU (1) YU40504B (xx)
ZA (1) ZA78365B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329349A (en) * 1979-07-25 1982-05-11 Sandoz, Inc. 6-C1-4 Alkyl-7-phenyl or substituted phenyl-1,6-naphthyridine-5(6H)-ones
DE3027619A1 (de) * 1979-07-25 1981-02-19 Sandoz Ag 6-alkyl-7-phenyl-1,6-naphtyradin- 5(6h)-on-derivate
JPS59116269A (ja) * 1982-12-24 1984-07-05 Nisshin Flour Milling Co Ltd イソカルボスチリル誘導体
DE3502831A1 (de) * 1985-01-29 1986-07-31 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung
US4698341A (en) * 1983-07-30 1987-10-06 Godecke Aktiengesellschaft Use of 1,6-naphthyridinone derivatives in treating pulmonary thrombosis
DE3423003A1 (de) * 1984-06-22 1986-01-02 Beiersdorf Ag, 2000 Hamburg Benzo(c)(1,8)naphthyridine, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPS6136266A (ja) * 1984-07-26 1986-02-20 Mitsui Toatsu Chem Inc イソキノリン誘導体およびそれを有効成分として含有する治療用組成物
WO1996004231A1 (fr) * 1994-08-04 1996-02-15 C & C Research Labs. Nouveau derive amine, procede d'obtention de ce derive et son utilisation comme antiarythmique
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
CN1960977B (zh) 2004-05-31 2010-07-21 万有制药株式会社 喹唑啉衍生物
MX2010013974A (es) * 2008-06-24 2011-01-14 Sanofi Aventis Isoquinolinas e isoquinolinonas 6-sustituidas.
RU2538588C2 (ru) * 2008-06-24 2015-01-10 Санофи-Авентис ЗАМЕЩЕННЫЕ ИЗИХИНОЛИНЫ И ИЗОХИНОЛИНОНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ Rho-КИНАЗЫ
DK2303845T3 (da) * 2008-06-24 2013-12-16 Sanofi Sa Bi- og polycyklisk substitueret isoquinolin og bi- og polycykliske substituerede isoquinolinderivater som rho-kinasehæmmere

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2538341A (en) * 1949-09-20 1951-01-16 Smith Kline French Lab Method for producing 1-hydroxyisoquinolines
US3432027A (en) * 1966-01-05 1969-03-11 Lily Tulip Cup Corp Dispensing container assembly
GB1394700A (en) * 1972-11-25 1975-05-21 Aspro Nicholas Ltd Pharmacologically active isoquinoline derivatives
AT330777B (de) * 1973-09-08 1976-07-26 Thomae Gmbh Dr K Verfahren zur herstellung von neuen isochinolinderivaten und deren salzen
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
SE7603371L (sv) * 1975-03-26 1976-09-27 Sandoz Ag Organiska foreningar, deras anvendning och framstellning
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof

Also Published As

Publication number Publication date
NO149502B (no) 1984-01-23
IL53857A0 (en) 1978-04-30
LU78919A1 (de) 1979-04-09
FI63393B (fi) 1983-02-28
DK149847B (da) 1986-10-13
PL204134A1 (pl) 1979-07-02
SU677654A3 (ru) 1979-07-30
SG42883G (en) 1985-01-11
JPS5392786A (en) 1978-08-15
AT361480B (de) 1981-03-10
NO780214L (no) 1978-07-25
ES465455A1 (es) 1978-09-16
FR2378014A1 (fr) 1978-08-18
FR2378014B1 (xx) 1981-05-29
BE863160A (fr) 1978-07-20
SE7800739L (sv) 1978-07-23
IE780139L (en) 1978-07-22
NO149502C (no) 1984-05-02
RO72911A (ro) 1981-11-24
CA1106846A (en) 1981-08-11
AU3258178A (en) 1979-07-26
US4154837A (en) 1979-05-15
AU516692B2 (en) 1981-06-18
PT67561B (de) 1980-03-03
NZ186287A (en) 1980-10-08
HK60083A (en) 1983-12-02
HU176895B (en) 1981-05-28
IE46376B1 (en) 1983-05-18
YU13478A (en) 1983-01-21
DK149847C (da) 1987-05-04
DD135283A5 (de) 1979-04-25
DE2702600A1 (de) 1978-07-27
IT1102816B (it) 1985-10-07
IL53857A (en) 1981-02-27
PL112130B1 (en) 1980-09-30
CH640227A5 (de) 1983-12-30
GB1568021A (en) 1980-05-21
FI773717A (fi) 1978-07-23
ATA11078A (de) 1980-08-15
YU40504B (en) 1986-02-28
PT67561A (de) 1978-02-01
PH13911A (en) 1980-11-04
CS195653B2 (en) 1980-02-29
NL7800717A (nl) 1978-07-25
MY8400275A (en) 1984-12-31
BG28573A3 (xx) 1980-05-15
GR64093B (en) 1980-01-22
DK30578A (da) 1978-07-23
ZA78365B (en) 1979-09-26
IT7847729A0 (it) 1978-01-20
SE444433B (sv) 1986-04-14

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MM Patent lapsed

Owner name: DR. KARL THOMAE GMBH