FI62062C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 3,-diklorfenon-0-(2-aminoetyl)-oximer - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara 3,-diklorfenon-0-(2-aminoetyl)-oximer Download PDFInfo
- Publication number
- FI62062C FI62062C FI760694A FI760694A FI62062C FI 62062 C FI62062 C FI 62062C FI 760694 A FI760694 A FI 760694A FI 760694 A FI760694 A FI 760694A FI 62062 C FI62062 C FI 62062C
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- FI
- Finland
- Prior art keywords
- formula
- compound
- defined above
- aminoethyl
- reacted
- Prior art date
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- -1 2-AMINOETHYL Chemical class 0.000 title description 25
- 230000001225 therapeutic effect Effects 0.000 title 2
- 150000001875 compounds Chemical class 0.000 claims description 72
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- 239000000460 chlorine Substances 0.000 claims description 27
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 claims description 19
- 239000000203 mixture Substances 0.000 claims description 15
- 150000003839 salts Chemical class 0.000 claims description 14
- 150000002923 oximes Chemical class 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 9
- 239000002585 base Substances 0.000 claims description 9
- 239000012458 free base Substances 0.000 claims description 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 8
- 229910052783 alkali metal Inorganic materials 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 150000001340 alkali metals Chemical class 0.000 claims description 6
- 229910052801 chlorine Inorganic materials 0.000 claims description 5
- 229910021529 ammonia Inorganic materials 0.000 claims description 4
- OXBLHERUFWYNTN-UHFFFAOYSA-M copper(I) chloride Chemical compound [Cu]Cl OXBLHERUFWYNTN-UHFFFAOYSA-M 0.000 claims description 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims description 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 3
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- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052794 bromium Inorganic materials 0.000 claims description 3
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- 239000010949 copper Substances 0.000 claims description 3
- 229910052736 halogen Inorganic materials 0.000 claims description 3
- 150000002367 halogens Chemical class 0.000 claims description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 229910017604 nitric acid Inorganic materials 0.000 claims description 3
- 125000006239 protecting group Chemical group 0.000 claims description 3
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- 125000005530 alkylenedioxy group Chemical group 0.000 claims description 2
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- 125000003544 oxime group Chemical group 0.000 claims description 2
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 2
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- 238000009472 formulation Methods 0.000 claims 1
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- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- MLGCXEBRWGEOQX-UHFFFAOYSA-N tetradifon Chemical compound C1=CC(Cl)=CC=C1S(=O)(=O)C1=CC(Cl)=C(Cl)C=C1Cl MLGCXEBRWGEOQX-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7503311 | 1975-03-20 | ||
| NL7503311A NL7503311A (nl) | 1975-03-20 | 1975-03-20 | Verbindingen met antidepressieve werking. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI760694A7 FI760694A7 (en, 2012) | 1976-09-21 |
| FI62062B FI62062B (fi) | 1982-07-30 |
| FI62062C true FI62062C (fi) | 1982-11-10 |
Family
ID=19823425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI760694A FI62062C (fi) | 1975-03-20 | 1976-03-17 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 3,-diklorfenon-0-(2-aminoetyl)-oximer |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4081552A (en, 2012) |
| JP (1) | JPS6026777B2 (en, 2012) |
| AR (2) | AR211009A1 (en, 2012) |
| AT (1) | AT342565B (en, 2012) |
| AU (1) | AU505357B2 (en, 2012) |
| BE (1) | BE839745A (en, 2012) |
| CA (1) | CA1077519A (en, 2012) |
| CH (3) | CH626056A5 (en, 2012) |
| DD (1) | DD125685A5 (en, 2012) |
| DE (1) | DE2609862A1 (en, 2012) |
| DK (1) | DK144034C (en, 2012) |
| ES (1) | ES446187A1 (en, 2012) |
| FI (1) | FI62062C (en, 2012) |
| FR (1) | FR2304337A1 (en, 2012) |
| GB (1) | GB1531613A (en, 2012) |
| GR (1) | GR59317B (en, 2012) |
| HU (1) | HU171027B (en, 2012) |
| IE (1) | IE43570B1 (en, 2012) |
| IL (1) | IL49233A (en, 2012) |
| IT (1) | IT1063060B (en, 2012) |
| NL (1) | NL7503311A (en, 2012) |
| PL (3) | PL100615B1 (en, 2012) |
| SE (1) | SE425388B (en, 2012) |
| SU (3) | SU670216A3 (en, 2012) |
| YU (1) | YU71376A (en, 2012) |
| ZA (1) | ZA761209B (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1110460B (it) * | 1977-03-02 | 1985-12-23 | Ciba Geigy Ag | Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego |
| CA1321950C (en) * | 1986-10-24 | 1993-09-07 | Robert A.B. Bannard | Metal oximate/polyethylene glycols chemical decontaminant system |
| FR2639942B1 (fr) * | 1988-12-02 | 1991-03-29 | Sanofi Sa | Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant |
| HUT54347A (en) * | 1989-01-10 | 1991-02-28 | Chinoin Gyogyszer Es Vegyeszet | Improved process for producing amidoximes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3692835A (en) * | 1967-04-05 | 1972-09-19 | Jan Van Dijk | Pharmacologically active amino-ethyl oximes |
-
1975
- 1975-03-20 NL NL7503311A patent/NL7503311A/xx not_active Application Discontinuation
-
1976
- 1976-02-27 SE SE7602716A patent/SE425388B/xx not_active IP Right Cessation
- 1976-03-01 ZA ZA761209A patent/ZA761209B/xx unknown
- 1976-03-10 DE DE19762609862 patent/DE2609862A1/de active Granted
- 1976-03-15 AR AR262560A patent/AR211009A1/es active
- 1976-03-17 SU SU762334810A patent/SU670216A3/ru active
- 1976-03-17 CH CH334476A patent/CH626056A5/de not_active IP Right Cessation
- 1976-03-17 PL PL1976188002A patent/PL100615B1/pl unknown
- 1976-03-17 GR GR50334A patent/GR59317B/el unknown
- 1976-03-17 HU HU76PI00000510A patent/HU171027B/hu not_active IP Right Cessation
- 1976-03-17 IT IT21324/76A patent/IT1063060B/it active
- 1976-03-17 CA CA248,106A patent/CA1077519A/en not_active Expired
- 1976-03-17 GB GB10702/76A patent/GB1531613A/en not_active Expired
- 1976-03-17 AT AT195376A patent/AT342565B/de not_active IP Right Cessation
- 1976-03-17 IL IL49233A patent/IL49233A/xx unknown
- 1976-03-17 DK DK115576A patent/DK144034C/da active
- 1976-03-17 FI FI760694A patent/FI62062C/fi not_active IP Right Cessation
- 1976-03-17 PL PL1976199549A patent/PL101884B1/pl unknown
- 1976-03-17 PL PL1976199548A patent/PL100050B1/pl unknown
- 1976-03-18 ES ES446187A patent/ES446187A1/es not_active Expired
- 1976-03-18 AU AU12146/76A patent/AU505357B2/en not_active Expired
- 1976-03-18 IE IE566/76A patent/IE43570B1/en unknown
- 1976-03-18 YU YU00713/76A patent/YU71376A/xx unknown
- 1976-03-18 DD DD191913A patent/DD125685A5/xx unknown
- 1976-03-18 BE BE165317A patent/BE839745A/xx not_active IP Right Cessation
- 1976-03-19 JP JP51029395A patent/JPS6026777B2/ja not_active Expired
- 1976-03-19 FR FR7608020A patent/FR2304337A1/fr active Granted
- 1976-03-19 US US05/668,454 patent/US4081552A/en not_active Expired - Lifetime
- 1976-12-02 AR AR265704A patent/AR212818A1/es active
-
1977
- 1977-07-11 SU SU772500952A patent/SU623517A3/ru active
- 1977-07-12 SU SU772503852A patent/SU626691A3/ru active
-
1981
- 1981-03-06 CH CH153781A patent/CH634828A5/de not_active IP Right Cessation
- 1981-03-06 CH CH153881A patent/CH629760A5/de not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: DUPHAR INTERNATIONAL RESEARCH B.V |