FI58495C - Analogifoerfarande foer framstaellning av terapeutiskt aktiv 1-(3-(4-m-klorfenyl-1-piperazinyl)-propyl)-3,4-dietyl- 2-1,2,4-triazolin-5-on och farmaceutiskt godtagbara salter daerav - Google Patents

Analogifoerfarande foer framstaellning av terapeutiskt aktiv 1-(3-(4-m-klorfenyl-1-piperazinyl)-propyl)-3,4-dietyl- 2-1,2,4-triazolin-5-on och farmaceutiskt godtagbara salter daerav Download PDF

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Publication number
FI58495C
FI58495C FI3188/73A FI318873A FI58495C FI 58495 C FI58495 C FI 58495C FI 3188/73 A FI3188/73 A FI 3188/73A FI 318873 A FI318873 A FI 318873A FI 58495 C FI58495 C FI 58495C
Authority
FI
Finland
Prior art keywords
triazolin
diethyl
treated
therapeutic activities
chloro
Prior art date
Application number
FI3188/73A
Other languages
English (en)
Finnish (fi)
Other versions
FI58495B (fi
Inventor
Giuseppe Palazzo
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of FI58495B publication Critical patent/FI58495B/fi
Application granted granted Critical
Publication of FI58495C publication Critical patent/FI58495C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
FI3188/73A 1972-10-16 1973-10-15 Analogifoerfarande foer framstaellning av terapeutiskt aktiv 1-(3-(4-m-klorfenyl-1-piperazinyl)-propyl)-3,4-dietyl- 2-1,2,4-triazolin-5-on och farmaceutiskt godtagbara salter daerav FI58495C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT5338072 1972-10-16
IT53380/72A IT1052119B (it) 1972-10-16 1972-10-16 Derivati del triazolinone e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
FI58495B FI58495B (fi) 1980-10-31
FI58495C true FI58495C (fi) 1981-02-10

Family

ID=11282276

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3188/73A FI58495C (fi) 1972-10-16 1973-10-15 Analogifoerfarande foer framstaellning av terapeutiskt aktiv 1-(3-(4-m-klorfenyl-1-piperazinyl)-propyl)-3,4-dietyl- 2-1,2,4-triazolin-5-on och farmaceutiskt godtagbara salter daerav

Country Status (19)

Country Link
US (1) US3857845A (fr)
JP (1) JPS5550948B2 (fr)
AR (1) AR204086A1 (fr)
AT (1) AT336021B (fr)
BE (1) BE806146A (fr)
CA (1) CA1013746A (fr)
CH (1) CH589643A5 (fr)
DE (1) DE2351739C3 (fr)
DK (1) DK141750B (fr)
ES (1) ES419687A1 (fr)
FI (1) FI58495C (fr)
FR (1) FR2202702B1 (fr)
GB (1) GB1438337A (fr)
IT (1) IT1052119B (fr)
KE (1) KE2823A (fr)
NL (1) NL184782C (fr)
NO (1) NO138565C (fr)
SE (1) SE390819B (fr)
YU (1) YU39914B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1047702B (it) * 1975-07-24 1980-10-20 Acraf Nuova sintesi degli psicofarmaci denominati trazodone ed eteroperidone
IT1073639B (it) * 1976-05-05 1985-04-17 Acraf Impiego del trazodone e etoperidone nel morbo di parikinson ed in altre sindromi extrapiramidali caratterizzate da tremori
US4162318A (en) * 1976-05-05 1979-07-24 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Use of trazodone and etoperidone in Parkinsonism and in other extrapyramidal syndromes characterized by tremors
US4465683A (en) * 1979-09-14 1984-08-14 Mead Johnson & Company Anti-psychotic agents
US4254124A (en) * 1979-09-24 1981-03-03 Mead Johnson & Company Antidepressant agent
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4386091A (en) * 1982-02-24 1983-05-31 Mead Johnson & Company 2-Phenoxyalkyl-1,2,4-triazol-3-one antidepressants
US4575555A (en) * 1983-06-29 1986-03-11 Mead Johnson & Company 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine derivative
US4613600A (en) * 1983-09-30 1986-09-23 Mead Johnson & Company Antidepressant 1,2,4-triazolone compounds
US4784998A (en) * 1987-04-06 1988-11-15 Bristol-Myers Company 1,3,4-oxadiazole pyschotropic compounds
US4931445A (en) * 1988-10-06 1990-06-05 Irwin Goldstein Agents for treatment of male impotence
US5140036A (en) * 1990-09-19 1992-08-18 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5229406A (en) * 1990-09-19 1993-07-20 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5087634A (en) * 1990-10-31 1992-02-11 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5238952A (en) * 1990-10-31 1993-08-24 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5196537A (en) * 1991-03-21 1993-03-23 G. D. Searle & Co. 5-apylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5164403A (en) * 1991-04-05 1992-11-17 G. D. Searle & Co. N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
IT1256387B (it) * 1992-11-13 1995-12-04 Acraf Procedimento per preparare triazoloni
CA2182241C (fr) * 1996-07-29 2002-09-17 Bo Lei Methodes pour la preparation de nefazodone
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
WO2012072665A1 (fr) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprenant de la pipampérone et des antagonistes/inhibiteurs de la recapture de la sérotonine

Also Published As

Publication number Publication date
IT1052119B (it) 1981-06-20
YU263473A (en) 1983-02-28
AT336021B (de) 1977-04-12
DK141750C (fr) 1980-11-03
DE2351739B2 (de) 1980-01-10
GB1438337A (fr) 1976-06-03
FR2202702A1 (fr) 1974-05-10
AR204086A1 (es) 1975-11-20
CH589643A5 (fr) 1977-07-15
YU39914B (en) 1985-06-30
KE2823A (en) 1978-03-31
SE390819B (sv) 1977-01-24
NL184782C (nl) 1989-11-01
JPS4993381A (fr) 1974-09-05
ATA871173A (de) 1976-08-15
NL7314204A (fr) 1974-04-18
US3857845A (en) 1974-12-31
CA1013746A (en) 1977-07-12
DE2351739A1 (de) 1974-04-18
DE2351739C3 (de) 1980-09-04
FI58495B (fi) 1980-10-31
FR2202702B1 (fr) 1976-07-02
ES419687A1 (es) 1976-10-16
DK141750B (da) 1980-06-09
JPS5550948B2 (fr) 1980-12-20
NO138565B (no) 1978-06-19
BE806146A (fr) 1974-02-15
NO138565C (no) 1978-09-27
NL184782B (nl) 1989-06-01

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