FI58126C - Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner - Google Patents

Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner Download PDF

Info

Publication number
FI58126C
FI58126C FI3989/73A FI398973A FI58126C FI 58126 C FI58126 C FI 58126C FI 3989/73 A FI3989/73 A FI 3989/73A FI 398973 A FI398973 A FI 398973A FI 58126 C FI58126 C FI 58126C
Authority
FI
Finland
Prior art keywords
phenyl
imidazo
methoxy
pyridine
group
Prior art date
Application number
FI3989/73A
Other languages
English (en)
Finnish (fi)
Other versions
FI58126B (fi
Inventor
Eberhard Kutter
Volkard Austel
Willi Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2305339A external-priority patent/DE2305339C3/de
Priority claimed from DE2361757A external-priority patent/DE2361757A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI58126B publication Critical patent/FI58126B/fi
Application granted granted Critical
Publication of FI58126C publication Critical patent/FI58126C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194Radicals derived from thio- or thiono carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI3989/73A 1973-02-03 1973-12-27 Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner FI58126C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2305339 1973-02-03
DE2305339A DE2305339C3 (de) 1973-02-03 1973-02-03 Imidazo [4,5-b] pyridine, ihre Herstellung und ihre Verwendung als Cardiötonica
DE2361757A DE2361757A1 (de) 1973-12-12 1973-12-12 Neue imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine
DE2361757 1973-12-12

Publications (2)

Publication Number Publication Date
FI58126B FI58126B (fi) 1980-08-29
FI58126C true FI58126C (fi) 1980-12-10

Family

ID=25764640

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3989/73A FI58126C (fi) 1973-02-03 1973-12-27 Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner

Country Status (24)

Country Link
JP (1) JPS5748556B2 (sv)
AT (1) AT332873B (sv)
BG (1) BG23902A3 (sv)
CA (1) CA1041502A (sv)
CH (1) CH605939A5 (sv)
CS (1) CS200169B2 (sv)
DD (1) DD108989A5 (sv)
DK (1) DK140760B (sv)
ES (1) ES422450A1 (sv)
FI (1) FI58126C (sv)
FR (1) FR2215968B1 (sv)
GB (1) GB1445824A (sv)
HK (1) HK4080A (sv)
HU (1) HU170909B (sv)
IE (1) IE39066B1 (sv)
IL (1) IL44127A (sv)
NL (1) NL173645C (sv)
NO (1) NO139386C (sv)
PH (1) PH14988A (sv)
PL (1) PL93127B1 (sv)
RO (2) RO79057A (sv)
SE (1) SE411451B (sv)
SU (2) SU563917A3 (sv)
YU (2) YU36955B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49109394A (sv) * 1973-02-27 1974-10-17
DE3132754A1 (de) * 1981-08-19 1983-03-03 Merck Patent Gmbh, 6100 Darmstadt "2-aryl-imidazo(4,5-b)pyridine, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung"
ES517193A0 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
IL68495A0 (en) * 1982-05-03 1983-07-31 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4772600A (en) * 1986-06-09 1988-09-20 A. H. Robins Company, Inc. Fused imidazoheterocyclic compounds and pharmaceutical compositions
JPH01190663A (ja) * 1988-01-22 1989-07-31 Terumo Corp システアミン誘導体及びこれを含有する抗リウマチ剤
US6653309B1 (en) 1999-04-26 2003-11-25 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme technical field of the invention
WO2011106039A1 (en) 2010-02-24 2011-09-01 Research Triangle Institute Arylpiperazone opioid receptor antagonists
CN103261170B (zh) 2010-12-24 2016-08-24 住友化学株式会社 稠杂环化合物及其用于害虫防治的用途
WO2013191189A1 (ja) * 2012-06-21 2013-12-27 住友化学株式会社 縮合複素環化合物
WO2013191188A1 (ja) 2012-06-22 2013-12-27 住友化学株式会社 縮合複素環化合物

Also Published As

Publication number Publication date
CH605939A5 (sv) 1978-10-13
DK140760C (sv) 1980-04-21
DD108989A5 (sv) 1974-10-12
PL93127B1 (sv) 1977-05-30
IL44127A (en) 1977-05-31
RO84276B (ro) 1984-07-30
RO79057A (ro) 1982-06-25
GB1445824A (en) 1976-08-11
JPS5748556B2 (sv) 1982-10-16
PH14988A (en) 1982-03-12
JPS49102693A (sv) 1974-09-27
NO139386C (no) 1979-02-28
HK4080A (en) 1980-02-08
NL173645C (nl) 1984-02-16
ES422450A1 (es) 1976-05-01
FI58126B (fi) 1980-08-29
BG23902A3 (en) 1977-11-10
ATA16474A (de) 1976-02-15
CA1041502A (en) 1978-10-31
NL173645B (nl) 1983-09-16
YU36956B (en) 1984-08-31
YU36955B (en) 1984-08-31
SU634673A3 (ru) 1978-11-25
FR2215968A1 (sv) 1974-08-30
IE39066L (en) 1974-08-03
AU6512974A (en) 1975-08-07
FR2215968B1 (sv) 1977-01-28
YU17674A (en) 1982-06-18
DK140760B (da) 1979-11-12
IL44127A0 (en) 1974-05-16
RO84276A (ro) 1984-05-23
SU563917A3 (ru) 1977-06-30
IE39066B1 (en) 1978-08-02
CS200169B2 (en) 1980-08-29
NO740327L (no) 1974-08-06
NL7401254A (sv) 1974-08-06
AT332873B (de) 1976-10-25
NO139386B (no) 1978-11-20
HU170909B (hu) 1977-09-28
SE411451B (sv) 1979-12-27
YU110480A (en) 1982-06-18

Similar Documents

Publication Publication Date Title
FI58126C (fi) Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner
DE2305339C3 (de) Imidazo [4,5-b] pyridine, ihre Herstellung und ihre Verwendung als Cardiötonica
US4430343A (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
EP0341104B1 (en) Substituted flavonoid compounds, their salts, their manufacture and medicines containing these materials
JPS6111955B2 (sv)
Greco et al. Synthesis of sydnones and sydnone imines
FI61899C (fi) Foerfarande foer framstaellning av antiflogistiska och antitrombotiska 6-substituerad-3-amino-4-fenyl-1h-pyrazolo(3,4-b)pyridiner
PL119520B1 (en) Process for preparing novel,condensed pyrimidine derivatives pirimidina
NO813066L (no) Isokinolinderivater, fremgangsmaate til deres fremstilling, farmasoeytiske tilberedninger, innhold og deres anvendelse
SU1356962A3 (ru) Способ получени производных карбостирила
SU1634136A3 (ru) Способ получени арилпиперазинилалкиленфенилгетероциклических соединений или их фармацевтически приемлемых кислотно-аддитивных солей
FI63029B (fi) Foerfarande foer framstaellning av ulcushaemmande n-substituerade 5,11-dihydro-(piperazin-1'-yl-alkanoyl)-6h-pyrido(2,3-b)(1,4)-benzodiazepin-6-on-derivater
US3960863A (en) Pyrido[1,2-a]pyrimidinone derivatives
FI57259B (fi) Foerfarande foer framstaellning av bronkolytiska och sekretolytiska 6,11-dihydro-6-metyl-5h-pyrido/2,3-b//1,5/benzodiazepin-5-oner och 5,11-dihydro-5-metyl-6h-pyrido/2,3-b//1,4/benzodiazepin-6-oner
SU416946A3 (ru) СПОСОБ ПОЛУЧЕНИЯ 1-БЕНЗОТИЕНО-[2,3-йг]-ПИРИМИДИНОВ
FI64371C (fi) Foerfarande foer framstaellning av kardiovaskulaera 5h,7h-imidazo(4,5-h)-isokinolin-4,6-dioner
SU428602A3 (ru) Способ получения основпозамещенных производных 1
LeMahieu et al. Synthesis and antiallergy activity of 5-oxo-5H-thiazolo [2, 3-b] quinazolinecarboxylic acids
FI67220C (fi) Foerfarande foer framstaellning av antitrombotiskt verkande 2-perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidiner
FI61882C (fi) Foerfarande foer framstaellning av antitrombotiskt verkande 3-iperazino-isokinoliner
DE2361757A1 (de) Neue imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine
SU1015828A3 (ru) Способ получени производных пиразоло-(1,5-с)хиназолина или их солей
US3849436A (en) Cyclization of 2-(3-aryl-5-pyrazolyl)benzoic acids,esters and amides to 2-arylpyrazolo(5,1-a)isoindol-8-ones
FI62531B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-yan-n-(n n-dimetylamino-propyl)-iminobensyl och syraaddit iossalter daerav
EP0287971B1 (en) Benzimidazole derivatives and process for their preparations