FI57749C - Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter Download PDF

Info

Publication number
FI57749C
FI57749C FI2349/74A FI234974A FI57749C FI 57749 C FI57749 C FI 57749C FI 2349/74 A FI2349/74 A FI 2349/74A FI 234974 A FI234974 A FI 234974A FI 57749 C FI57749 C FI 57749C
Authority
FI
Finland
Prior art keywords
pyridyl
formula
piperidyl
phenylalkyl
acid
Prior art date
Application number
FI2349/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI234974A (ja
FI57749B (fi
Inventor
Adolf Langbein
Herbert Merz
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI234974A publication Critical patent/FI234974A/fi
Publication of FI57749B publication Critical patent/FI57749B/fi
Application granted granted Critical
Publication of FI57749C publication Critical patent/FI57749C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI2349/74A 1973-08-20 1974-08-07 Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter FI57749C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2341965A DE2341965C3 (de) 1973-08-20 1973-08-20 4- [N- (o-PyridyD- N-acyl] -aminolphenäthylpiperidine, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Schmerzzuständen
DE2341965 1973-08-20

Publications (3)

Publication Number Publication Date
FI234974A FI234974A (ja) 1975-02-21
FI57749B FI57749B (fi) 1980-06-30
FI57749C true FI57749C (fi) 1980-10-10

Family

ID=5890196

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2349/74A FI57749C (fi) 1973-08-20 1974-08-07 Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter

Country Status (26)

Country Link
US (1) US3933832A (ja)
JP (1) JPS5049285A (ja)
AT (2) AT334900B (ja)
BE (1) BE818989A (ja)
BG (1) BG24669A3 (ja)
CA (1) CA1041513A (ja)
CH (2) CH603630A5 (ja)
CS (2) CS181767B2 (ja)
DD (1) DD114260A5 (ja)
DE (1) DE2341965C3 (ja)
DK (1) DK141097C (ja)
ES (2) ES429221A1 (ja)
FI (1) FI57749C (ja)
FR (1) FR2241314B1 (ja)
GB (1) GB1468283A (ja)
HU (1) HU167563B (ja)
IE (1) IE40511B1 (ja)
IL (1) IL45494A (ja)
NL (1) NL7410989A (ja)
NO (1) NO140594C (ja)
PH (1) PH11999A (ja)
PL (2) PL91562B1 (ja)
RO (2) RO63458A (ja)
SE (1) SE402285B (ja)
SU (2) SU507229A3 (ja)
ZA (1) ZA745306B (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191683A (en) * 1975-05-28 1980-03-04 Ciba-Geigy Corporation Derivatives of 4-aminopiperidine as stabilizers for polymers
US4225606A (en) * 1975-09-23 1980-09-30 Janssen Pharmaceutica N.V. N-Aryl-N-(1-L-4-piperidinyl)arylacetamides
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
DK1379520T3 (da) 2001-02-23 2006-08-21 Merck & Co Inc N-substituerede ikke-aryl-heterocykliske NMDA/NR2B-antagonister
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20060263401A1 (en) * 2001-07-13 2006-11-23 Flow Focusing, Inc. Formulation and Method for Preventing Infection
US20040142013A1 (en) * 2001-07-13 2004-07-22 Flow Focusing, Inc. Implantable orthopedic surgical devices with controlled release antimicrobial component
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
US7592360B2 (en) * 2003-06-04 2009-09-22 Merck & Co., Inc. 3-fluoro-piperidines as NMDA/NR2B antagonists
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) * 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) * 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
US8933101B2 (en) * 2007-04-23 2015-01-13 Janssen Pharmaceutica Nv Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
AU2008240727C1 (en) * 2007-04-23 2013-10-03 Janssen Pharmaceutica N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
WO2008128995A1 (en) * 2007-04-23 2008-10-30 Janssen Pharmaceutica N.V. 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
WO2010000456A1 (en) * 2008-07-03 2010-01-07 Janssen Pharmaceutica Nv Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists
US8895562B2 (en) * 2008-07-31 2014-11-25 Janssen Pharmaceutica Nv Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1232147B (de) * 1961-04-13 1967-01-12 Bayer Ag Verfahren zur Herstellung von acylierten N-(Alkylaminoalkyl)-aminopyridinen
NL135583C (ja) * 1961-10-10
US3141823A (en) * 1962-09-04 1964-07-21 Res Lab Dr C Janssen N V Method for producing analgesia
IL25840A (en) * 1965-07-24 1969-12-31 Bayer Ag Optically active pyridine derivatives and their production

Also Published As

Publication number Publication date
DE2341965A1 (de) 1975-03-06
FI234974A (ja) 1975-02-21
SE402285B (sv) 1978-06-26
US3933832A (en) 1976-01-20
NL7410989A (nl) 1975-02-24
GB1468283A (en) 1977-03-23
IL45494A (en) 1977-07-31
CS181767B2 (en) 1978-03-31
FR2241314B1 (ja) 1977-11-10
DD114260A5 (ja) 1975-07-20
AU7248974A (en) 1976-02-19
RO63050A (ja) 1978-05-15
SU507229A3 (ru) 1976-03-15
PL91562B1 (ja) 1977-03-31
SE7410540L (ja) 1975-02-21
DE2341965B2 (de) 1978-06-01
ATA651274A (de) 1976-06-15
FI57749B (fi) 1980-06-30
FR2241314A1 (ja) 1975-03-21
NO140594B (no) 1979-06-25
CH603630A5 (ja) 1978-08-31
PL91512B1 (ja) 1977-02-28
PH11999A (en) 1978-10-06
CH603631A5 (ja) 1978-08-31
ES429221A1 (es) 1976-08-16
CA1041513A (en) 1978-10-31
DE2341965C3 (de) 1979-01-25
BG24669A3 (en) 1978-04-12
DK141097B (da) 1980-01-14
AT334901B (de) 1977-02-10
BE818989A (fr) 1975-02-19
DK141097C (da) 1980-08-18
AT334900B (de) 1977-02-10
HU167563B (ja) 1975-11-28
ES429234A1 (es) 1976-08-16
SU504480A3 (ru) 1976-02-25
IE40511B1 (en) 1979-06-20
DK439974A (ja) 1975-04-28
NO140594C (no) 1979-10-03
ATA651374A (de) 1976-06-15
CS182263B2 (en) 1978-04-28
ZA745306B (en) 1976-04-28
NO742970L (ja) 1975-03-17
JPS5049285A (ja) 1975-05-01
IE40511L (en) 1975-02-20
RO63458A (fr) 1978-06-15
IL45494A0 (en) 1974-11-29

Similar Documents

Publication Publication Date Title
FI57749C (fi) Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter
FI104631B (fi) Menetelmä uusien 1-asyyli-2-aralkyyli-4-(alkyyli)-aminopiperidiiniyhdisteiden valmistamiseksi
JP3833116B2 (ja) ビフェニル誘導体、その製法及び薬剤としての使用
US4472403A (en) Quinoline derivatives and pharmaceutical compositions and methods for treating cardiovascular disease with such compounds
US4547508A (en) 1-Phenylisoquinoline derivatives, pharmaceutical products containing these compounds and their use
Turner et al. Studies on imidazole compounds. I. 4-Methylimidazole and related compounds
GB2085880A (en) 1-carboxyalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing thhese compounds and their therapeutic application
WO2014192030A2 (en) An improved process for preparation of dabigatran etexilate and pharmaceutically acceptable acid addition salts thereof
FI89166B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva heterocykliska foereningar
MXPA02006499A (es) Derivados de fenilpiperazinilo.
JP2006520361A (ja) メラノコルチン−４受容体調節物質としての置換ピペリジンおよびピペラジン誘導体
AU705683B2 (en) Piperazino derivatives as neurokinin antagonists
FI66373C (fi) Foerfarande foer framstaellning av farmakologiskt verksamma n-xacyklyl-alkyl-piperidiner
NO159999B (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive substituerte 2-fenyl-2-(pyridyloksy)-etylamin-derivater og isostere forbindelser.
SU747424A3 (ru) Способ получени -арил- (1- -4-пиперидинил) ацетамидов или их солей
FI71936C (fi) Foerfarande foer framstaellning av neuroleptiskt aktiva 2-substituerade-8-fluor-5-(4-fluorfenyl)-2,3,4,4a, 5,9b-hexahydro-4a,9b-trans-1h-pyrido/4,3-b/indolderivat.
CA1263118A (en) 1,6-naphthyridine derivatives, process for the preparation and use thereof
GB2142021A (en) 1 4-dihydropyridine derivatives their preparation and pharmaceutical compositions containing them
AU2005210496B2 (en) Methods for making 4-Tetrazolyl-4-Phenylpiperidine compounds
JPS6348869B2 (ja)
EP1870396B1 (en) Benzyloxypropylamine derivative
CA1295332C (en) Hydropyridine derivatives
SU670216A3 (ru) Способ получени производных оксима или их солей
US5599938A (en) Process for preparing a piperidine derivative
KR101471987B1 (ko) 일정한 ｃｎｓ-관련 질환을 치료하기 위한 2-알킬-인다졸 화합물