CS182263B2 - Method of producing new amides of n-(1-w-phenylalkyl/-piperidyl-4)-n-/alfa-pyridyl/-carboxylic acid - Google Patents

Method of producing new amides of n-(1-w-phenylalkyl/-piperidyl-4)-n-/alfa-pyridyl/-carboxylic acid

Info

Publication number
CS182263B2
CS182263B2 CS7400005455A CS545574A CS182263B2 CS 182263 B2 CS182263 B2 CS 182263B2 CS 7400005455 A CS7400005455 A CS 7400005455A CS 545574 A CS545574 A CS 545574A CS 182263 B2 CS182263 B2 CS 182263B2
Authority
CS
Czechoslovakia
Prior art keywords
phenylalkyl
alfa
piperidyl
pyridyl
carboxylic acid
Prior art date
Application number
CS7400005455A
Other languages
English (en)
Inventor
Adolf Langbein
Herbert Merz
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of CS182263B2 publication Critical patent/CS182263B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CS7400005455A 1973-08-20 1974-07-31 Method of producing new amides of n-(1-w-phenylalkyl/-piperidyl-4)-n-/alfa-pyridyl/-carboxylic acid CS182263B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2341965A DE2341965C3 (de) 1973-08-20 1973-08-20 4- [N- (o-PyridyD- N-acyl] -aminolphenäthylpiperidine, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Schmerzzuständen

Publications (1)

Publication Number Publication Date
CS182263B2 true CS182263B2 (en) 1978-04-28

Family

ID=5890196

Family Applications (2)

Application Number Title Priority Date Filing Date
CS7400005455A CS182263B2 (en) 1973-08-20 1974-07-31 Method of producing new amides of n-(1-w-phenylalkyl/-piperidyl-4)-n-/alfa-pyridyl/-carboxylic acid
CS7400005454A CS181767B2 (en) 1973-08-20 1974-07-31 Method of producing new amides n-(1-(u phenylalkyl)-piperidyl-4)-n-/alfa-pyridyl/carboxylic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS7400005454A CS181767B2 (en) 1973-08-20 1974-07-31 Method of producing new amides n-(1-(u phenylalkyl)-piperidyl-4)-n-/alfa-pyridyl/carboxylic acid

Country Status (26)

Country Link
US (1) US3933832A (cs)
JP (1) JPS5049285A (cs)
AT (2) AT334900B (cs)
BE (1) BE818989A (cs)
BG (1) BG24669A3 (cs)
CA (1) CA1041513A (cs)
CH (2) CH603630A5 (cs)
CS (2) CS182263B2 (cs)
DD (1) DD114260A5 (cs)
DE (1) DE2341965C3 (cs)
DK (1) DK141097C (cs)
ES (2) ES429221A1 (cs)
FI (1) FI57749C (cs)
FR (1) FR2241314B1 (cs)
GB (1) GB1468283A (cs)
HU (1) HU167563B (cs)
IE (1) IE40511B1 (cs)
IL (1) IL45494A (cs)
NL (1) NL7410989A (cs)
NO (1) NO140594C (cs)
PH (1) PH11999A (cs)
PL (2) PL91562B1 (cs)
RO (2) RO63050A (cs)
SE (1) SE402285B (cs)
SU (2) SU507229A3 (cs)
ZA (1) ZA745306B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191683A (en) * 1975-05-28 1980-03-04 Ciba-Geigy Corporation Derivatives of 4-aminopiperidine as stabilizers for polymers
US4225606A (en) * 1975-09-23 1980-09-30 Janssen Pharmaceutica N.V. N-Aryl-N-(1-L-4-piperidinyl)arylacetamides
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
DK1379520T3 (da) * 2001-02-23 2006-08-21 Merck & Co Inc N-substituerede ikke-aryl-heterocykliske NMDA/NR2B-antagonister
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
US20040142013A1 (en) * 2001-07-13 2004-07-22 Flow Focusing, Inc. Implantable orthopedic surgical devices with controlled release antimicrobial component
US20060263401A1 (en) * 2001-07-13 2006-11-23 Flow Focusing, Inc. Formulation and Method for Preventing Infection
US7592360B2 (en) * 2003-06-04 2009-09-22 Merck & Co., Inc. 3-fluoro-piperidines as NMDA/NR2B antagonists
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) * 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
CN101663299A (zh) * 2007-04-23 2010-03-03 詹森药业有限公司 作为快速解离性多巴胺2受体拮抗剂的噻(二)唑类化合物
EP2148873B1 (en) * 2007-04-23 2012-08-29 Janssen Pharmaceutica, N.V. 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
EP2148872A1 (en) * 2007-04-23 2010-02-03 Janssen Pharmaceutica, N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
WO2010000456A1 (en) * 2008-07-03 2010-01-07 Janssen Pharmaceutica Nv Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists
JP5457450B2 (ja) * 2008-07-31 2014-04-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 迅速解離性ドーパミン２受容体拮抗薬としてのピペラジン−１−イル−トリフルオロメチル−置換−ピリジン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1232147B (de) * 1961-04-13 1967-01-12 Bayer Ag Verfahren zur Herstellung von acylierten N-(Alkylaminoalkyl)-aminopyridinen
BE623427A (cs) * 1961-10-10
US3141823A (en) * 1962-09-04 1964-07-21 Res Lab Dr C Janssen N V Method for producing analgesia
IL25840A (en) * 1965-07-24 1969-12-31 Bayer Ag Optically active pyridine derivatives and their production

Also Published As

Publication number Publication date
ES429221A1 (es) 1976-08-16
NO742970L (cs) 1975-03-17
IL45494A0 (en) 1974-11-29
US3933832A (en) 1976-01-20
PL91512B1 (cs) 1977-02-28
IL45494A (en) 1977-07-31
GB1468283A (en) 1977-03-23
DE2341965A1 (de) 1975-03-06
DD114260A5 (cs) 1975-07-20
JPS5049285A (cs) 1975-05-01
ATA651274A (de) 1976-06-15
SU504480A3 (ru) 1976-02-25
FI57749C (fi) 1980-10-10
CA1041513A (en) 1978-10-31
NO140594B (no) 1979-06-25
BE818989A (fr) 1975-02-19
PL91562B1 (cs) 1977-03-31
FI234974A (cs) 1975-02-21
IE40511B1 (en) 1979-06-20
CH603630A5 (cs) 1978-08-31
DE2341965B2 (de) 1978-06-01
PH11999A (en) 1978-10-06
BG24669A3 (en) 1978-04-12
ZA745306B (en) 1976-04-28
FR2241314B1 (cs) 1977-11-10
DK141097B (da) 1980-01-14
NL7410989A (nl) 1975-02-24
DK141097C (da) 1980-08-18
DE2341965C3 (de) 1979-01-25
AT334900B (de) 1977-02-10
CH603631A5 (cs) 1978-08-31
DK439974A (cs) 1975-04-28
AT334901B (de) 1977-02-10
ATA651374A (de) 1976-06-15
SE7410540L (cs) 1975-02-21
RO63458A (fr) 1978-06-15
IE40511L (en) 1975-02-20
CS181767B2 (en) 1978-03-31
FR2241314A1 (cs) 1975-03-21
ES429234A1 (es) 1976-08-16
RO63050A (cs) 1978-05-15
SU507229A3 (ru) 1976-03-15
FI57749B (fi) 1980-06-30
NO140594C (no) 1979-10-03
HU167563B (cs) 1975-11-28
SE402285B (sv) 1978-06-26
AU7248974A (en) 1976-02-19

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