FI3844189T3 - Annostusstrategia, joka lieventää bispesifisten CD3/CD20-vasta-aineiden sytokiinien vapautumisoireyhtymää - Google Patents

Annostusstrategia, joka lieventää bispesifisten CD3/CD20-vasta-aineiden sytokiinien vapautumisoireyhtymää Download PDF

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Publication number
FI3844189T3
FI3844189T3 FIEP19782800.7T FI19782800T FI3844189T3 FI 3844189 T3 FI3844189 T3 FI 3844189T3 FI 19782800 T FI19782800 T FI 19782800T FI 3844189 T3 FI3844189 T3 FI 3844189T3
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FI
Finland
Prior art keywords
dose
therapeutic protein
subject
use according
lymphoma
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FIEP19782800.7T
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English (en)
Finnish (fi)
Inventor
Carrie Brownstein
Israel Lowy
Lieve Lucille Adriaens
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Regeneron Pharma
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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FIEP19782800.7T 2018-08-31 2019-08-30 Annostusstrategia, joka lieventää bispesifisten CD3/CD20-vasta-aineiden sytokiinien vapautumisoireyhtymää FI3844189T3 (fi)

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US201862726137P 2018-08-31 2018-08-31
US201862774019P 2018-11-30 2018-11-30
US201962861100P 2019-06-13 2019-06-13
PCT/US2019/049027 WO2020047389A1 (en) 2018-08-31 2019-08-30 Dosing strategy that mitigates cytokine release syndrome for cd3/c20 bispecific antibodies

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FI3844189T3 true FI3844189T3 (fi) 2025-03-05

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US (2) US11590223B2 (enExample)
EP (2) EP3844189B1 (enExample)
JP (2) JP7605734B2 (enExample)
KR (2) KR20210054528A (enExample)
CN (1) CN112771077B (enExample)
AU (2) AU2019331024B2 (enExample)
CA (1) CA3110513A1 (enExample)
DK (1) DK3844189T3 (enExample)
ES (1) ES3009025T3 (enExample)
FI (1) FI3844189T3 (enExample)
HR (1) HRP20250234T1 (enExample)
HU (1) HUE070384T2 (enExample)
IL (1) IL280875B2 (enExample)
LT (1) LT3844189T (enExample)
MA (1) MA53495A (enExample)
MX (2) MX2021002190A (enExample)
PL (1) PL3844189T3 (enExample)
PT (1) PT3844189T (enExample)
RS (1) RS66543B1 (enExample)
SI (1) SI3844189T1 (enExample)
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TW202504917A (zh) 2018-06-21 2025-02-01 美商再生元醫藥公司 用雙特異性抗CD3xMUC16抗體及抗PD-1抗體治療癌症之方法
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