FI117900B - Menetelmä solun valmistamiseksi, joka ilmentää soluvälitteisen immuuniteetin uudelleensuuntaavia reseptorikimeeroja, ja niitä koodaava DNA ja vektori - Google Patents
Menetelmä solun valmistamiseksi, joka ilmentää soluvälitteisen immuuniteetin uudelleensuuntaavia reseptorikimeeroja, ja niitä koodaava DNA ja vektori Download PDFInfo
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- C07K—PEPTIDES
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US66596191A | 1991-03-07 | 1991-03-07 | |
US66596191 | 1991-03-07 | ||
US9201785 | 1992-03-06 | ||
PCT/US1992/001785 WO1992015322A1 (en) | 1991-03-07 | 1992-03-06 | Redirection of cellular immunity by receptor chimeras |
Publications (3)
Publication Number | Publication Date |
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FI933882A FI933882A (fi) | 1993-09-06 |
FI933882A0 FI933882A0 (fi) | 1993-09-06 |
FI117900B true FI117900B (fi) | 2007-04-13 |
Family
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Application Number | Title | Priority Date | Filing Date |
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FI933882A FI117900B (fi) | 1991-03-07 | 1993-09-06 | Menetelmä solun valmistamiseksi, joka ilmentää soluvälitteisen immuuniteetin uudelleensuuntaavia reseptorikimeeroja, ja niitä koodaava DNA ja vektori |
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EP (1) | EP0574512B1 (hu) |
JP (1) | JP3696232B2 (hu) |
KR (1) | KR100257780B1 (hu) |
AT (1) | ATE232107T1 (hu) |
AU (2) | AU662136B2 (hu) |
BR (1) | BR9205736A (hu) |
CA (1) | CA2104957C (hu) |
CZ (1) | CZ281881B6 (hu) |
DE (1) | DE69232921T2 (hu) |
DK (1) | DK0574512T3 (hu) |
ES (1) | ES2191006T3 (hu) |
FI (1) | FI117900B (hu) |
HK (1) | HK1011935A1 (hu) |
HU (1) | HU218732B (hu) |
IE (1) | IE920716A1 (hu) |
IL (1) | IL101147A (hu) |
MX (1) | MX9201002A (hu) |
NO (1) | NO317202B1 (hu) |
NZ (1) | NZ241855A (hu) |
PT (1) | PT100207B (hu) |
RU (1) | RU2161044C2 (hu) |
SK (1) | SK283643B6 (hu) |
UA (1) | UA41870C2 (hu) |
WO (1) | WO1992015322A1 (hu) |
Families Citing this family (142)
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EP0517895B1 (en) * | 1990-12-14 | 1996-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
US6407221B1 (en) | 1990-12-14 | 2002-06-18 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
US5843728A (en) * | 1991-03-07 | 1998-12-01 | The General Hospital Corporation | Redirection of cellular immunity by receptor chimeras |
US5912170A (en) * | 1991-03-07 | 1999-06-15 | The General Hospital Corporation | Redirection of cellular immunity by protein-tyrosine kinase chimeras |
US6753162B1 (en) | 1991-03-07 | 2004-06-22 | The General Hospital Corporation | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
US5851828A (en) * | 1991-03-07 | 1998-12-22 | The General Hospital Corporation | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
US6004811A (en) | 1991-03-07 | 1999-12-21 | The Massachussetts General Hospital | Redirection of cellular immunity by protein tyrosine kinase chimeras |
US7049136B2 (en) | 1991-03-07 | 2006-05-23 | The General Hospital Corporation | Redirection of cellular immunity by receptor chimeras |
IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
NZ269312A (en) * | 1993-07-16 | 1998-02-26 | Gen Hospital Corp | Mammalian cell which expresses a membrane bound chimeric receptor comprising an intracellular portion of tyrosine kinase and an extracellular portion specific for a target cell or agent |
WO1995026985A1 (en) * | 1994-04-05 | 1995-10-12 | Board Of Regents, The University Of Texas System | Modified receptors that continuously signal |
EP0758394B1 (en) | 1994-05-02 | 2002-11-20 | Bernd Groner | Bifunctional protein, preparation and use |
US5798100A (en) * | 1994-07-06 | 1998-08-25 | Immunomedics, Inc. | Multi-stage cascade boosting vaccine |
US7354587B1 (en) | 1994-07-06 | 2008-04-08 | Immunomedics, Inc. | Use of immunoconjugates to enhance the efficacy of multi-stage cascade boosting vaccines |
KR100384249B1 (ko) * | 1994-08-02 | 2003-08-30 | 더 제너럴 하스피탈 코포레이션 | Cd4 디코이 수용체 포함세포 및 관련 분자 및 방법 |
US5741899A (en) * | 1995-02-02 | 1998-04-21 | Cell Genesys, Inc. | Chimeric receptors comprising janus kinase for regulating cellular pro liferation |
US6103521A (en) * | 1995-02-06 | 2000-08-15 | Cell Genesys, Inc. | Multispecific chimeric receptors |
NZ302513A (en) * | 1995-02-24 | 1999-11-29 | Gen Hospital Corp | Chimeric receptors for redirecting cellular immunity |
US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
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JP2001503260A (ja) * | 1996-10-23 | 2001-03-13 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 改良されたワクチン |
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