SK283643B6 - Bunka poskytujúca expresiou proteínovej membrány viazaný chimérny receptor, chimérny receptor, vektor, DNA a protilátka - Google Patents

Info

Publication number

SK283643B6

SK283643B6 SK956-93A SK95693A SK283643B6 SK 283643 B6 SK283643 B6 SK 283643B6 SK 95693 A SK95693 A SK 95693A SK 283643 B6 SK283643 B6 SK 283643B6

Authority

SK

Slovakia

Prior art keywords

leu

gly

ser

gin

wall

Prior art date

1991-03-07

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• 230000007969 cellular immunity Effects 0.000 title description 2
• 108700010039 chimeric receptor Proteins 0.000 claims abstract description 38
• 206010028980 Neoplasm Diseases 0.000 claims abstract description 16
• 210000004027 cell Anatomy 0.000 claims description 318
• 108090000623 proteins and genes Proteins 0.000 claims description 61
• 230000003834 intracellular effect Effects 0.000 claims description 54
• 102000005962 receptors Human genes 0.000 claims description 48
• 108020003175 receptors Proteins 0.000 claims description 48
• 150000001413 amino acids Chemical class 0.000 claims description 41
• 239000012634 fragment Substances 0.000 claims description 39
• 102000004169 proteins and genes Human genes 0.000 claims description 36
• 210000001744 T-lymphocyte Anatomy 0.000 claims description 35
• 108010087819 Fc receptors Proteins 0.000 claims description 30
• 102000009109 Fc receptors Human genes 0.000 claims description 30
• 239000000427 antigen Substances 0.000 claims description 24
• 102000036639 antigens Human genes 0.000 claims description 23
• 108091007433 antigens Proteins 0.000 claims description 23
• 230000027455 binding Effects 0.000 claims description 22
• 108091008875 B cell receptors Proteins 0.000 claims description 16
• 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims description 16
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• 239000003795 chemical substances by application Substances 0.000 claims description 14
• 239000012528 membrane Substances 0.000 claims description 14
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• 101100205189 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) leu-5 gene Proteins 0.000 claims description 6
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• 108010048397 seryl-lysyl-leucine Proteins 0.000 claims description 6
• 108010045269 tryptophyltryptophan Proteins 0.000 claims description 6
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