FI115444B - Uusi menetelmä lääkkeen valmistamiseksi - Google Patents

Uusi menetelmä lääkkeen valmistamiseksi Download PDF

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Publication number
FI115444B
FI115444B FI961221A FI961221A FI115444B FI 115444 B FI115444 B FI 115444B FI 961221 A FI961221 A FI 961221A FI 961221 A FI961221 A FI 961221A FI 115444 B FI115444 B FI 115444B
Authority
FI
Finland
Prior art keywords
progesterone
att
levels
polymer
serum
Prior art date
Application number
FI961221A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI961221A0 (fi
FI961221A (fi
Inventor
William Joseph Bologna
Howard Leslie Levine
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402302&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI115444(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of FI961221A0 publication Critical patent/FI961221A0/fi
Publication of FI961221A publication Critical patent/FI961221A/fi
Application granted granted Critical
Publication of FI115444B publication Critical patent/FI115444B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI961221A 1993-09-15 1996-03-15 Uusi menetelmä lääkkeen valmistamiseksi FI115444B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12237193 1993-09-15
US08/122,371 US5543150A (en) 1993-09-15 1993-09-15 Method of progesterone delivery and affect thereof
US9410270 1994-09-13
PCT/US1994/010270 WO1995007699A1 (en) 1993-09-15 1994-09-13 Novel method of progesterone delivery and affect thereof

Publications (3)

Publication Number Publication Date
FI961221A0 FI961221A0 (fi) 1996-03-15
FI961221A FI961221A (fi) 1996-05-14
FI115444B true FI115444B (fi) 2005-05-13

Family

ID=22402302

Family Applications (1)

Application Number Title Priority Date Filing Date
FI961221A FI115444B (fi) 1993-09-15 1996-03-15 Uusi menetelmä lääkkeen valmistamiseksi

Country Status (27)

Country Link
US (1) US5543150A (uk)
EP (1) EP0719146B1 (uk)
JP (1) JP3143474B2 (uk)
KR (1) KR100278553B1 (uk)
AT (1) ATE174796T1 (uk)
BR (1) BR9407475A (uk)
CA (1) CA2171939C (uk)
CO (1) CO4290332A1 (uk)
DE (1) DE69415543T2 (uk)
DK (1) DK0719146T3 (uk)
ES (1) ES2126783T3 (uk)
FI (1) FI115444B (uk)
GR (1) GR3029314T3 (uk)
HU (1) HU221583B (uk)
IL (1) IL110972A (uk)
LT (1) LT4072B (uk)
LV (1) LV11527B (uk)
MA (1) MA23329A1 (uk)
MY (1) MY111484A (uk)
NO (1) NO308585B1 (uk)
NZ (1) NZ273816A (uk)
PE (1) PE50795A1 (uk)
PH (1) PH30813A (uk)
RU (1) RU2148393C1 (uk)
UA (1) UA37244C2 (uk)
WO (1) WO1995007699A1 (uk)
ZA (1) ZA947073B (uk)

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US6056972A (en) * 1997-02-26 2000-05-02 Dimera, Llc Method for reducing coronary artery reactivity
US6602487B1 (en) 1997-02-26 2003-08-05 Dimera Incorporated Methods and tests for producing and for inhibiting coronary artery vasospasms
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
EP1356806A1 (en) * 1997-09-12 2003-10-29 Columbia Laboratories (Bermuda) Limited A pharmaceutical composition for treating dysmenorrhea and premature labor
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
WO1999018942A1 (en) * 1997-10-10 1999-04-22 Imperial College Innovations Ltd. Use of csaidtm compounds for the management of uterine contractions
US6306914B1 (en) 1997-10-21 2001-10-23 Columbia Laboratories, Inc. Progestin therapy for maintaining amenorrhea
AU4406899A (en) * 1998-05-20 1999-12-06 Bent Formby Progesterone treatment of cancer
IL127129A (en) * 1998-11-18 2004-06-01 Ferring Bv Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared
US20070178139A1 (en) * 1998-11-18 2007-08-02 Yankov Vladimir I Vaginally administratable progesterone-containing tablets and method for preparing same
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
US6544553B1 (en) * 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
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CN1845723B (zh) * 2003-09-03 2010-07-21 迷斯康贸易有限公司 子宫内膜异位症的治疗方法
KR101288265B1 (ko) * 2003-09-03 2013-07-26 미스콘 트레이딩 에스.에이. 자궁 내막증의 치료 방법
US20060292223A1 (en) * 2005-06-16 2006-12-28 Warner Chilcott Company Inc, Gel compositions for topical administration
WO2006138686A1 (en) * 2005-06-16 2006-12-28 Warner Chilcott Company, Inc. Estrogen compositions for vaginal administration
JP5193196B2 (ja) * 2006-06-02 2013-05-08 ペア ツリー ウーマンズ ヘルス ケア 萎縮性膣炎の治療の方法
US8828981B2 (en) * 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
ES2310968B1 (es) 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
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US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
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CA2713943C (en) * 2008-02-04 2018-10-23 Teva Women's Health, Inc. Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
US9107696B2 (en) 2008-08-06 2015-08-18 Emory University Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
US8421747B2 (en) 2008-09-24 2013-04-16 Microsoft Corporation Object detection and user settings
ES2344675B1 (es) 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
JP5894143B2 (ja) * 2010-03-22 2016-03-23 リプロス セラピューティクス インコーポレイテッド 抗黄体ホルモンの無毒送達のための組成物および方法
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8435972B2 (en) 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
CN103648482B (zh) * 2011-07-15 2018-01-02 根特大学 阴道内递送系统
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
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US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
MX367596B (es) * 2012-01-26 2019-08-27 Therapeuticsmd Inc Tratamientos transdermicos de sustitucion hormonal.
NZ702467A (en) 2012-05-31 2016-07-29 Repros Therapeutics Inc Formulations and methods for vaginal delivery of antiprogestins
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103239389A (zh) * 2013-06-03 2013-08-14 南京泽恒医药技术开发有限公司 一种治疗先兆性流产的黄体酮缓释凝胶的制备方法
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US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
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Also Published As

Publication number Publication date
DE69415543D1 (de) 1999-02-04
HUT76824A (en) 1997-11-28
ZA947073B (en) 1995-05-02
AU689133B2 (en) 1998-03-26
IL110972A0 (en) 1994-11-28
FI961221A0 (fi) 1996-03-15
JPH09502724A (ja) 1997-03-18
US5543150A (en) 1996-08-06
PE50795A1 (es) 1996-01-19
IL110972A (en) 1998-03-10
EP0719146A1 (en) 1996-07-03
HU221583B (hu) 2002-11-28
HU9600669D0 (en) 1996-05-28
NZ273816A (en) 2007-09-28
FI961221A (fi) 1996-05-14
PH30813A (en) 1997-10-17
CO4290332A1 (es) 1996-04-17
UA37244C2 (uk) 2001-05-15
LT4072B (en) 1996-11-25
MY111484A (en) 2000-06-30
NO961044D0 (no) 1996-03-14
AU7726194A (en) 1995-04-03
LV11527A (lv) 1996-10-20
MA23329A1 (fr) 1995-04-01
KR100278553B1 (ko) 2001-01-15
BR9407475A (pt) 1996-11-12
EP0719146B1 (en) 1998-12-23
WO1995007699A1 (en) 1995-03-23
NO308585B1 (no) 2000-10-02
LT96027A (en) 1996-07-25
DK0719146T3 (da) 1999-08-23
DE69415543T2 (de) 1999-06-17
CA2171939C (en) 2002-01-01
ES2126783T3 (es) 1999-04-01
GR3029314T3 (en) 1999-05-28
RU2148393C1 (ru) 2000-05-10
CA2171939A1 (en) 1995-03-23
ATE174796T1 (de) 1999-01-15
JP3143474B2 (ja) 2001-03-07
NO961044L (no) 1996-05-14
LV11527B (en) 1997-02-20

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