FI115054B - Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi Download PDF

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Publication number
FI115054B
FI115054B FI910925A FI910925A FI115054B FI 115054 B FI115054 B FI 115054B FI 910925 A FI910925 A FI 910925A FI 910925 A FI910925 A FI 910925A FI 115054 B FI115054 B FI 115054B
Authority
FI
Finland
Prior art keywords
methyl
oxo
oxetanyl
group
alkyl
Prior art date
Application number
FI910925A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI910925A (fi
FI910925A0 (fi
Inventor
Hans Peter Maerki
Andre Szente
Henri Stalder
Romano Derungs
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI910925A0 publication Critical patent/FI910925A0/fi
Publication of FI910925A publication Critical patent/FI910925A/fi
Application granted granted Critical
Publication of FI115054B publication Critical patent/FI115054B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
FI910925A 1990-02-26 1991-02-26 Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi FI115054B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH60490 1990-02-26
CH60490 1990-02-26
CH400590 1990-12-17
CH400590 1990-12-17

Publications (3)

Publication Number Publication Date
FI910925A0 FI910925A0 (fi) 1991-02-26
FI910925A FI910925A (fi) 1991-08-27
FI115054B true FI115054B (fi) 2005-02-28

Family

ID=25685091

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910925A FI115054B (fi) 1990-02-26 1991-02-26 Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi

Country Status (18)

Country Link
EP (1) EP0444482B1 (fr)
JP (1) JP2753403B2 (fr)
KR (1) KR0183036B1 (fr)
AT (1) ATE133167T1 (fr)
AU (1) AU645291B2 (fr)
CA (1) CA2035967C (fr)
DE (1) DE59107262D1 (fr)
DK (1) DK0444482T3 (fr)
ES (1) ES2082869T3 (fr)
FI (1) FI115054B (fr)
GR (1) GR3019618T3 (fr)
HU (1) HU218272B (fr)
IE (1) IE72196B1 (fr)
IL (1) IL97148A (fr)
MC (1) MC2226A1 (fr)
NO (1) NO177055C (fr)
NZ (1) NZ237170A (fr)
PT (1) PT96887B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2035972C (fr) * 1990-02-23 2006-07-11 Martin Karpf Procede de preparation d'oxetanones
CA2098167C (fr) * 1992-06-24 2006-12-19 Dorothea Isler Aliments pour humains et animaux contenant un inhibiteur de la lipase
NL1004559C2 (nl) * 1996-11-18 1998-05-19 Unilife Boter.
CA2358921A1 (fr) * 1999-10-29 2001-05-10 John Jason Gentry Mullins Derives d'oxetanone
US6342519B2 (en) * 1999-10-29 2002-01-29 2 Pro Chemical Oxetanone derivatives
US6348492B1 (en) * 1999-10-29 2002-02-19 2Pro Chemical Oxetanone derivatives
US7074822B2 (en) 2004-02-23 2006-07-11 Solvay Pharmaceuticals Gmbh Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them
DE102004009076A1 (de) * 2004-02-23 2005-10-27 Solvay Pharmaceuticals Gmbh Alkylcarbamat-substituierte β-Lactone, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP2212305A4 (fr) * 2007-10-31 2011-10-26 Burnham Inst Medical Research Composés de bêta-lactone
BR112020000635B1 (pt) * 2017-07-12 2023-04-18 Mayo Foundation For Medical Education And Research Inibidores de lipases, seus usos e composição farmacêutica

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608117B2 (ja) * 1977-02-08 1985-02-28 財団法人微生物化学研究会 新生理活性物質エステラスチンおよびその製造法
GB2023604B (en) * 1978-05-25 1982-07-28 Microbial Chem Res Found Physiologically active derivatives of esterastin and production thereof
JPH0669130B2 (ja) * 1984-08-09 1994-08-31 三菱電機株式会社 遅延線

Also Published As

Publication number Publication date
EP0444482A3 (en) 1991-12-04
PT96887B (pt) 1998-09-30
JP2753403B2 (ja) 1998-05-20
NO910729L (no) 1991-08-27
CA2035967C (fr) 2001-10-16
IE910631A1 (en) 1991-08-28
NZ237170A (en) 1993-12-23
HU218272B (en) 2000-07-28
CA2035967A1 (fr) 1991-08-27
EP0444482A2 (fr) 1991-09-04
ATE133167T1 (de) 1996-02-15
NO177055C (no) 1995-07-12
EP0444482B1 (fr) 1996-01-17
PT96887A (pt) 1991-10-31
FI910925A (fi) 1991-08-27
NO177055B (no) 1995-04-03
AU7122891A (en) 1991-08-29
ES2082869T3 (es) 1996-04-01
KR0183036B1 (ko) 1999-05-01
FI910925A0 (fi) 1991-02-26
KR910021391A (ko) 1991-12-20
IL97148A (en) 1996-11-14
MC2226A1 (fr) 1993-02-02
NO910729D0 (no) 1991-02-25
AU645291B2 (en) 1994-01-13
GR3019618T3 (en) 1996-07-31
JPH0770099A (ja) 1995-03-14
HUT56557A (en) 1991-09-30
IE72196B1 (en) 1997-03-26
IL97148A0 (en) 1992-05-25
DE59107262D1 (de) 1996-02-29
DK0444482T3 (da) 1996-05-06

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