FI114639B - Ihmisen sappisuolojen stimuloimat lipaasijohdannaiset ja menetelmä niitä sisältävän farmaseuttisen koostumuksen valmistamiseksi - Google Patents

Ihmisen sappisuolojen stimuloimat lipaasijohdannaiset ja menetelmä niitä sisältävän farmaseuttisen koostumuksen valmistamiseksi Download PDF

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Publication number
FI114639B
FI114639B FI925453A FI925453A FI114639B FI 114639 B FI114639 B FI 114639B FI 925453 A FI925453 A FI 925453A FI 925453 A FI925453 A FI 925453A FI 114639 B FI114639 B FI 114639B
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FI
Finland
Prior art keywords
protein
eller
dna sequence
amino acid
sequence
Prior art date
Application number
FI925453A
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English (en)
Finnish (fi)
Swedish (sv)
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FI925453A0 (fi
FI925453A (fi
Inventor
Lars Blaeckberg
Olle Hernell
Peter Carlsson
Thomas Olivecrona
Karl Gunnar Bjursell
Curt Sven Magnus Enerbaeck
Jeanette Annika Nilsson
Original Assignee
Arexis Ab
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Publication of FI925453A0 publication Critical patent/FI925453A0/fi
Publication of FI925453A publication Critical patent/FI925453A/fi
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI925453A 1990-06-01 1992-11-30 Ihmisen sappisuolojen stimuloimat lipaasijohdannaiset ja menetelmä niitä sisältävän farmaseuttisen koostumuksen valmistamiseksi FI114639B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9001985A SE9001985D0 (sv) 1990-06-01 1990-06-01 New chemical products
SE9001985 1990-06-01
SE9100381 1991-05-30
PCT/SE1991/000381 WO1991018923A1 (en) 1990-06-01 1991-05-30 Derivatives of human bile-salt stimulated lipase, and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
FI925453A0 FI925453A0 (fi) 1992-11-30
FI925453A FI925453A (fi) 1992-11-30
FI114639B true FI114639B (fi) 2004-11-30

Family

ID=20379662

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925453A FI114639B (fi) 1990-06-01 1992-11-30 Ihmisen sappisuolojen stimuloimat lipaasijohdannaiset ja menetelmä niitä sisältävän farmaseuttisen koostumuksen valmistamiseksi

Country Status (44)

Country Link
EP (1) EP0535048B1 (pt)
JP (1) JPH05507201A (pt)
KR (1) KR100212411B1 (pt)
CN (2) CN1075113C (pt)
AP (1) AP207A (pt)
AT (1) ATE151077T1 (pt)
AU (1) AU651979B2 (pt)
BG (1) BG61165B1 (pt)
CA (1) CA2083396C (pt)
CZ (1) CZ287470B6 (pt)
DE (1) DE69125489T2 (pt)
DK (1) DK0535048T3 (pt)
DZ (1) DZ1503A1 (pt)
EG (1) EG19937A (pt)
ES (1) ES2099159T3 (pt)
FI (1) FI114639B (pt)
GR (1) GR3023618T3 (pt)
HK (1) HK62497A (pt)
HR (1) HRP920771B1 (pt)
HU (1) HU215258B (pt)
IE (1) IE911844A1 (pt)
IL (1) IL98273A (pt)
IS (1) IS1751B (pt)
JO (1) JO1694B1 (pt)
LT (1) LT4020B (pt)
LV (1) LV10292B (pt)
MA (1) MA22166A1 (pt)
MY (1) MY111245A (pt)
NO (1) NO322962B1 (pt)
NZ (1) NZ238223A (pt)
PH (1) PH30761A (pt)
PL (1) PL166534B1 (pt)
PT (1) PT97836B (pt)
RO (1) RO114793B1 (pt)
RU (1) RU2140983C1 (pt)
SE (1) SE9001985D0 (pt)
SG (1) SG48078A1 (pt)
SK (1) SK281089B6 (pt)
TN (1) TNSN91041A1 (pt)
TW (1) TW221712B (pt)
UA (1) UA39165C2 (pt)
WO (1) WO1991018923A1 (pt)
YU (1) YU49138B (pt)
ZA (1) ZA913778B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP930935A2 (en) * 1992-06-11 1994-12-31 Astra Ab New dna sequences
SE9300686D0 (sv) 1993-03-01 1993-03-01 Astra Ab Novel polypeptides
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð
FR2754827B1 (fr) * 1996-10-17 1998-12-24 Biocem Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) * 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
WO2007063405A2 (en) * 2005-12-01 2007-06-07 University Of Bergen Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes using human cel gene
EP3205351B1 (en) 2010-04-23 2023-04-12 Alexion Pharmaceuticals, Inc. Lysosomal storage disease enzyme
NZ700824A (en) 2010-09-09 2016-03-31 Synageva Biopharma Corp Use of lysosomal acid lipase for treating lysosomal acid lipase deficiency in patients
EP2629789A1 (en) 2010-10-21 2013-08-28 Swedish Orphan Biovitrum AB (Publ) Method to increase the absorption of unsaturated fatty acids by human infants
JP5850940B2 (ja) * 2010-10-21 2016-02-03 スウェディッシュ オーファン バイオビトラム パブリーク アクチエボラグ ヒト乳児の発育速度を増大させる方法
CN111032864A (zh) 2017-06-19 2020-04-17 瑞典孤儿比奥维特鲁姆有限公司 具有半衰期延长多肽的融合蛋白
JP2022545718A (ja) 2019-08-30 2022-10-28 コデクシス， インコーポレイテッド 操作されたリパーゼ改変体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2142337A (en) * 1983-07-01 1985-01-16 Celltech Ltd Preparation of lingual lipase protein

Also Published As

Publication number Publication date
AP207A (en) 1992-08-18
AU651979B2 (en) 1994-08-11
HK62497A (en) 1997-05-16
LTIP1736A (en) 1995-08-25
MY111245A (en) 1999-10-30
GR3023618T3 (en) 1997-08-29
IS3710A7 (is) 1991-12-02
FI925453A0 (fi) 1992-11-30
IE911844A1 (en) 1991-12-04
JPH05507201A (ja) 1993-10-21
CA2083396C (en) 2006-09-19
CA2083396A1 (en) 1991-12-02
EG19937A (en) 2000-12-31
YU95191A (sh) 1994-06-10
NO924528L (no) 1992-11-24
ES2099159T3 (es) 1997-05-16
HRP920771B1 (en) 1999-10-31
TNSN91041A1 (fr) 1992-10-25
PL166534B1 (pl) 1995-05-31
DE69125489T2 (de) 1997-08-14
LT4020B (en) 1996-08-26
SE9001985D0 (sv) 1990-06-01
HU9203774D0 (en) 1993-03-29
CZ164491A3 (cs) 1999-07-14
RO114793B1 (ro) 1999-07-30
DZ1503A1 (fr) 2004-09-13
LV10292A (lv) 1994-10-20
HUT63184A (en) 1993-07-28
IL98273A (en) 2005-11-20
RU2140983C1 (ru) 1999-11-10
UA39165C2 (uk) 2001-06-15
TW221712B (pt) 1994-03-11
NZ238223A (en) 1993-05-26
NO924528D0 (no) 1992-11-24
PT97836B (pt) 1998-11-30
ZA913778B (en) 1992-02-26
WO1991018923A1 (en) 1991-12-12
AU7964591A (en) 1991-12-31
IL98273A0 (en) 1992-06-21
SK281089B6 (sk) 2000-11-07
DK0535048T3 (da) 1997-09-29
CN1064313A (zh) 1992-09-09
DE69125489D1 (de) 1997-05-07
HRP920771A2 (en) 1997-04-30
SG48078A1 (en) 1998-04-17
FI925453A (fi) 1992-11-30
ATE151077T1 (de) 1997-04-15
IS1751B (is) 2000-07-21
SK164491A3 (en) 1995-07-11
MA22166A1 (fr) 1991-12-31
CN1326782A (zh) 2001-12-19
PT97836A (pt) 1992-02-28
BG61165B1 (bg) 1997-01-31
JO1694B1 (en) 1992-08-09
EP0535048B1 (en) 1997-04-02
HU215258B (hu) 1998-11-30
NO322962B1 (no) 2006-12-18
LV10292B (en) 1995-08-20
KR100212411B1 (en) 1999-08-02
PH30761A (en) 1997-10-17
YU49138B (sh) 2004-03-12
CN1075113C (zh) 2001-11-21
CZ287470B6 (cs) 2000-12-13
EP0535048A1 (en) 1993-04-07
AP9100270A0 (en) 1991-07-31

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