DK0535048T3 - Derivater af humant galdesalt-stimuleret lipase og farmaceutiske præparater indeholdende disse - Google Patents

Derivater af humant galdesalt-stimuleret lipase og farmaceutiske præparater indeholdende disse

Info

Publication number
DK0535048T3
DK0535048T3 DK91911030.4T DK91911030T DK0535048T3 DK 0535048 T3 DK0535048 T3 DK 0535048T3 DK 91911030 T DK91911030 T DK 91911030T DK 0535048 T3 DK0535048 T3 DK 0535048T3
Authority
DK
Denmark
Prior art keywords
derivatives
pharmaceutical compositions
compositions containing
bile salt
human bile
Prior art date
Application number
DK91911030.4T
Other languages
Danish (da)
English (en)
Inventor
Gunnar Bjursell
Lars Blaeckberg
Peter Carlsson
Sven Enerbaeck
Olle Hernell
Jeanette Nilsson
Thomas Olivecrona
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of DK0535048T3 publication Critical patent/DK0535048T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK91911030.4T 1990-06-01 1991-05-30 Derivater af humant galdesalt-stimuleret lipase og farmaceutiske præparater indeholdende disse DK0535048T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9001985A SE9001985D0 (sv) 1990-06-01 1990-06-01 New chemical products

Publications (1)

Publication Number Publication Date
DK0535048T3 true DK0535048T3 (da) 1997-09-29

Family

ID=20379662

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91911030.4T DK0535048T3 (da) 1990-06-01 1991-05-30 Derivater af humant galdesalt-stimuleret lipase og farmaceutiske præparater indeholdende disse

Country Status (44)

Country Link
EP (1) EP0535048B1 (pt)
JP (1) JPH05507201A (pt)
KR (1) KR100212411B1 (pt)
CN (2) CN1075113C (pt)
AP (1) AP207A (pt)
AT (1) ATE151077T1 (pt)
AU (1) AU651979B2 (pt)
BG (1) BG61165B1 (pt)
CA (1) CA2083396C (pt)
CZ (1) CZ287470B6 (pt)
DE (1) DE69125489T2 (pt)
DK (1) DK0535048T3 (pt)
DZ (1) DZ1503A1 (pt)
EG (1) EG19937A (pt)
ES (1) ES2099159T3 (pt)
FI (1) FI114639B (pt)
GR (1) GR3023618T3 (pt)
HK (1) HK62497A (pt)
HR (1) HRP920771B1 (pt)
HU (1) HU215258B (pt)
IE (1) IE911844A1 (pt)
IL (1) IL98273A (pt)
IS (1) IS1751B (pt)
JO (1) JO1694B1 (pt)
LT (1) LT4020B (pt)
LV (1) LV10292B (pt)
MA (1) MA22166A1 (pt)
MY (1) MY111245A (pt)
NO (1) NO322962B1 (pt)
NZ (1) NZ238223A (pt)
PH (1) PH30761A (pt)
PL (1) PL166534B1 (pt)
PT (1) PT97836B (pt)
RO (1) RO114793B1 (pt)
RU (1) RU2140983C1 (pt)
SE (1) SE9001985D0 (pt)
SG (1) SG48078A1 (pt)
SK (1) SK281089B6 (pt)
TN (1) TNSN91041A1 (pt)
TW (1) TW221712B (pt)
UA (1) UA39165C2 (pt)
WO (1) WO1991018923A1 (pt)
YU (1) YU49138B (pt)
ZA (1) ZA913778B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616483A (en) * 1992-06-11 1997-04-01 Aktiebolaget Astra Genomic DNA sequences encoding human BSSL/CEL
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð
SE9300686D0 (sv) 1993-03-01 1993-03-01 Astra Ab Novel polypeptides
FR2754827B1 (fr) * 1996-10-17 1998-12-24 Biocem Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
US20090226904A1 (en) * 2005-12-01 2009-09-10 University Of Bergen Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes
CA2995446C (en) * 2010-04-23 2020-05-12 Synageva Biopharma Corp Lysosomal storage disease enzyme
BR122019021757B1 (pt) 2010-09-09 2020-12-08 Alexion Pharmaceuticals, Inc composição farmacêutica para tratamento de um paciente humano sofrendo de uma deficiência de lipase ácida lisossomal (lal)
CN103189070A (zh) 2010-10-21 2013-07-03 瑞典孤儿比奥维特鲁姆有限公司 增加人婴儿对不饱和脂肪酸之吸收的方法
ES2603328T3 (es) 2010-10-21 2017-02-27 Swedish Orphan Biovitrum Ab (Publ) Método para incrementar la tasa de crecimiento de lactantes humanos
BR112019025973A2 (pt) * 2017-06-19 2020-07-07 Swedish Orphan Biovitrum Ab (Publ) proteína de fusão com polipeptídeo de extensão de meia-vida
MX2022002473A (es) 2019-08-30 2022-08-02 Codexis Inc Variantes de lipasa modificadas geneticamente.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000381A1 (en) * 1983-07-01 1985-01-31 Celltech Limited Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production

Also Published As

Publication number Publication date
MA22166A1 (fr) 1991-12-31
BG61165B1 (bg) 1997-01-31
LTIP1736A (en) 1995-08-25
TW221712B (pt) 1994-03-11
DZ1503A1 (fr) 2004-09-13
SE9001985D0 (sv) 1990-06-01
CA2083396C (en) 2006-09-19
DE69125489T2 (de) 1997-08-14
LT4020B (en) 1996-08-26
SK281089B6 (sk) 2000-11-07
CZ287470B6 (cs) 2000-12-13
NZ238223A (en) 1993-05-26
NO924528D0 (no) 1992-11-24
HRP920771A2 (en) 1997-04-30
AU7964591A (en) 1991-12-31
UA39165C2 (uk) 2001-06-15
CN1326782A (zh) 2001-12-19
FI925453A (fi) 1992-11-30
PH30761A (en) 1997-10-17
EP0535048A1 (en) 1993-04-07
HRP920771B1 (en) 1999-10-31
IS1751B (is) 2000-07-21
EG19937A (en) 2000-12-31
AP207A (en) 1992-08-18
CA2083396A1 (en) 1991-12-02
HU9203774D0 (en) 1993-03-29
LV10292A (lv) 1994-10-20
ZA913778B (en) 1992-02-26
YU49138B (sh) 2004-03-12
NO924528L (no) 1992-11-24
NO322962B1 (no) 2006-12-18
HUT63184A (en) 1993-07-28
CN1064313A (zh) 1992-09-09
PT97836A (pt) 1992-02-28
PL166534B1 (pl) 1995-05-31
GR3023618T3 (en) 1997-08-29
WO1991018923A1 (en) 1991-12-12
SK164491A3 (en) 1995-07-11
BG97123A (bg) 1993-12-24
YU95191A (sh) 1994-06-10
KR100212411B1 (en) 1999-08-02
PT97836B (pt) 1998-11-30
IL98273A0 (en) 1992-06-21
AU651979B2 (en) 1994-08-11
HK62497A (en) 1997-05-16
FI114639B (fi) 2004-11-30
TNSN91041A1 (fr) 1992-10-25
JO1694B1 (en) 1992-08-09
AP9100270A0 (en) 1991-07-31
RO114793B1 (ro) 1999-07-30
FI925453A0 (fi) 1992-11-30
LV10292B (en) 1995-08-20
JPH05507201A (ja) 1993-10-21
DE69125489D1 (de) 1997-05-07
ATE151077T1 (de) 1997-04-15
CZ164491A3 (cs) 1999-07-14
MY111245A (en) 1999-10-30
HU215258B (hu) 1998-11-30
EP0535048B1 (en) 1997-04-02
IE911844A1 (en) 1991-12-04
CN1075113C (zh) 2001-11-21
SG48078A1 (en) 1998-04-17
IS3710A7 (is) 1991-12-02
IL98273A (en) 2005-11-20
RU2140983C1 (ru) 1999-11-10
ES2099159T3 (es) 1997-05-16

Similar Documents

Publication Publication Date Title
IS1896B (is) Framleiðsla og kristalform af 2-methýl-thíeno-bensodíasepín
DK0861089T3 (da) Metoder og sammensætninger til indgivelse af monomere proteiner
DK1167364T3 (da) Benzopyranholdige forbindelser og promedikamentformer af disse
DK0470514T3 (da) Carbostyrilderivater og farmaceutiske præparater indeholdende disse
BR9407799A (pt) Composição de matéria método de tratamento e composição farmaceutica
NO930194D0 (no) Fremgangsmaate og anordning for mikromoenstringer av overflater
NO921485D0 (no) Fremgangsmaate og anlegg for avhendelse av borkaks
DK516689A (da) Instrument til perkutan fjernelse af thromber og emboli
NO914315D0 (no) Fremgangsmaate og sammensetning for surgjoering av underjordiske formasjoner
DK51493A (da) Laegemiddel indeholdende humant interleukin-1alfa og anvendelse af interleukin-1alfa til fremstilling af et saadant laegemiddel
DK0535048T3 (da) Derivater af humant galdesalt-stimuleret lipase og farmaceutiske præparater indeholdende disse
BR9303442A (pt) Aplicacao de aminas graxas oxalquiladas e de derivados de aminas graxas
DK110791D0 (da) Fremgangsmaade og anvendelse af porphyriner
DK0517761T3 (da) Lipaseholdig flydende pre-spotter og anvendelsen af en sådan pre-spotter
BR9403947A (pt) Composição de matéria e formulação oral multicomponente de rapamicina
IL114534A0 (en) Heterocyclic derivatives of azolones their preparaion and pharmaceutical compositions containing them
IS5223A (is) Lyfjasamsetningar af tizoxaníði og nitazoxaníði
DK0508334T3 (da) Aminophenolderivater og farmaceutiske præparater indeholdende disse
DK522888D0 (da) Heterocykliske derivater og farmaceutiske praeparater med indhold af saadanne
NO952266D0 (no) Klorfluoretersammensetninger og preparater av disse
IL110944A (en) 5-Cyclobutenedione derivatives of indolylalkylpiperazinyl pyridines and pyrimidines and pharmaceutical compositions containing them
DK449188A (da) 2'-deoxy-5-fluoruridinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DE69309582D1 (de) Endlos Formularsatz und dadurch erstelltes Poststück
DK127187D0 (da) Farmaceutisk kombination af t-pa og oxypurinol
DK508689D0 (da) Organofluorider af tin og fremgangsmaade til fremstilling heraf