FI114633B - Menetelmä farmaseuttisesti käyttökelpoisten heteroetikkahappojohdannaisten valmistamiseksi - Google Patents

Menetelmä farmaseuttisesti käyttökelpoisten heteroetikkahappojohdannaisten valmistamiseksi Download PDF

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Publication number
FI114633B
FI114633B FI933260A FI933260A FI114633B FI 114633 B FI114633 B FI 114633B FI 933260 A FI933260 A FI 933260A FI 933260 A FI933260 A FI 933260A FI 114633 B FI114633 B FI 114633B
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FI
Finland
Prior art keywords
eller
hydroxy
lower alkyl
aryl
halogen
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FI933260A
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English (en)
Finnish (fi)
Swedish (sv)
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FI933260A (fi
FI933260A0 (fi
Inventor
Naokata Yokoyama
Gordon Northrop Walker
Alan Joseph Main
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Novartis Ag
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Publication of FI933260A0 publication Critical patent/FI933260A0/fi
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Publication of FI114633B publication Critical patent/FI114633B/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/33Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring
    • C07C323/35Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group
    • C07C323/37Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/18Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/56Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI933260A 1992-07-21 1993-07-19 Menetelmä farmaseuttisesti käyttökelpoisten heteroetikkahappojohdannaisten valmistamiseksi FI114633B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91854492A 1992-07-21 1992-07-21
US91854492 1992-07-21

Publications (3)

Publication Number Publication Date
FI933260A0 FI933260A0 (fi) 1993-07-19
FI933260A FI933260A (fi) 1994-01-22
FI114633B true FI114633B (fi) 2004-11-30

Family

ID=25440554

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933260A FI114633B (fi) 1992-07-21 1993-07-19 Menetelmä farmaseuttisesti käyttökelpoisten heteroetikkahappojohdannaisten valmistamiseksi

Country Status (19)

Country Link
US (3) US5401772A (ar)
EP (1) EP0580550B1 (ar)
JP (1) JP3616119B2 (ar)
KR (1) KR100294381B1 (ar)
AT (1) ATE159515T1 (ar)
AU (1) AU667924B2 (ar)
CA (1) CA2100817C (ar)
DE (1) DE69314718T2 (ar)
DK (1) DK0580550T3 (ar)
ES (1) ES2108855T3 (ar)
FI (1) FI114633B (ar)
GR (1) GR3025517T3 (ar)
HU (1) HU214875B (ar)
IL (1) IL106360A0 (ar)
NO (1) NO304111B1 (ar)
NZ (1) NZ248181A (ar)
SA (1) SA94140579B1 (ar)
TW (1) TW350771B (ar)
ZA (1) ZA935196B (ar)

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Also Published As

Publication number Publication date
FI933260A (fi) 1994-01-22
ZA935196B (en) 1994-07-07
DE69314718T2 (de) 1998-02-26
EP0580550B1 (en) 1997-10-22
AU4208193A (en) 1994-01-27
KR940005555A (ko) 1994-03-21
KR100294381B1 (ko) 2001-09-17
IL106360A0 (en) 1993-11-15
JPH06172275A (ja) 1994-06-21
EP0580550A1 (en) 1994-01-26
NO304111B1 (no) 1998-10-26
DK0580550T3 (da) 1998-02-02
HUT64512A (en) 1994-01-28
JP3616119B2 (ja) 2005-02-02
SA94140579B1 (ar) 2006-07-10
FI933260A0 (fi) 1993-07-19
ES2108855T3 (es) 1998-01-01
US5569674A (en) 1996-10-29
HU214875B (hu) 1998-07-28
CA2100817C (en) 2004-10-12
DE69314718D1 (de) 1997-11-27
AU667924B2 (en) 1996-04-18
US5401772A (en) 1995-03-28
CA2100817A1 (en) 1994-01-22
NO932614L (no) 1994-01-24
GR3025517T3 (en) 1998-02-27
NZ248181A (en) 1995-11-27
HU9302095D0 (en) 1993-10-28
US5654468A (en) 1997-08-05
ATE159515T1 (de) 1997-11-15
TW350771B (en) 1999-01-21
NO932614D0 (no) 1993-07-20

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