CH609024A5 - Process for the preparation of new sulphur-containing diaryl and oxygen-containing diaryl compounds - Google Patents
Process for the preparation of new sulphur-containing diaryl and oxygen-containing diaryl compoundsInfo
- Publication number
- CH609024A5 CH609024A5 CH1204875A CH1204875A CH609024A5 CH 609024 A5 CH609024 A5 CH 609024A5 CH 1204875 A CH1204875 A CH 1204875A CH 1204875 A CH1204875 A CH 1204875A CH 609024 A5 CH609024 A5 CH 609024A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- containing diaryl
- oxygen
- preparation
- new sulphur
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Abstract
Compounds of formula: <IMAGE> where one of A and B is O, S, SO or SO2 and the other O, are prepared by reaction of the corresponding compounds ClC6H4-A-C6H4BH and Hal-Alk-R. The compounds obtained, especially the esters (R = COOC2H5) and the cyano compounds (R = CN), can then be converted to the corresponding derivatives, especially to carboxylic acids and their salts or to amidines. These compounds are novel and can be used for the treatment of circulatory disorders, especially cardiovascular diseases.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4238774A GB1519147A (en) | 1974-09-30 | 1974-09-30 | Sulphur and oxygen-containing diaryl compounds |
GB158775 | 1975-01-14 | ||
FR7502307A FR2258846A1 (en) | 1974-01-25 | 1975-01-24 | Bis((N-hydroxy alkyl)-amino alkyl thio)alkane and derivs - as agents preventing blood platelet aggregation |
Publications (1)
Publication Number | Publication Date |
---|---|
CH609024A5 true CH609024A5 (en) | 1979-02-15 |
Family
ID=27250408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1204875A CH609024A5 (en) | 1974-09-30 | 1975-09-17 | Process for the preparation of new sulphur-containing diaryl and oxygen-containing diaryl compounds |
Country Status (6)
Country | Link |
---|---|
CA (1) | CA1064504A (en) |
CH (1) | CH609024A5 (en) |
DE (2) | DE2560602C2 (en) |
DK (1) | DK146336C (en) |
IE (1) | IE42609B1 (en) |
NL (1) | NL176776C (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1571829A (en) | 1976-04-06 | 1980-07-23 | Lafon Labor | Sulphur-containing diaryl compounds and oxygen-containing diaryl compounds |
ATE159515T1 (en) * | 1992-07-21 | 1997-11-15 | Ciba Geigy Ag | OXAMIC ACID DERIVATIVES AS HYPOCHOLESTEREMIC AGENTS |
ES2256053T3 (en) | 1999-11-01 | 2006-07-16 | Taisho Pharmaceutical Co., Ltd | INHIBITOR OF THE 20-HETE PRODUCTION ENZYME. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1935344U (en) | 1965-11-09 | 1966-03-24 | Karosserie Migoe Chr H Mittelg | DOUBLE WALL FOR VEHICLE BODIES, ESPECIALLY FOR REFRIGERATION AND THERMAL CARRIAGE OD. THE EQUAL, WHERE THE SPACE BETWEEN TWO WALLS IS FILLED WITH INSULATING MATERIAL. |
CH511786A (en) * | 1968-01-11 | 1971-08-31 | Hoechst Ag | Process for the preparation of phenoxyalkanecarboxylic acids, their salts and esters |
DE1668896C3 (en) | 1968-01-11 | 1974-08-29 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Phenoxyalkanecarboxylic acids, their salts and esters, and processes for the preparation of these compounds |
BE786644A (en) * | 1971-07-23 | 1973-01-24 | Hoechst Ag | PHENOXY-4 PHENOXY-ALKANE-CARBOXYL ACID DERIVATIVES THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM |
FI55986C (en) * | 1972-05-10 | 1979-11-12 | Ciba Geigy Ag | FOER ANVAENDNING SOM SKADEDJURS BEKAEMPNINGSMEDEL AVSEDDA SUBSTITUERADE FENYLDERIVAT |
DE2223894C3 (en) * | 1972-05-17 | 1981-07-23 | Hoechst Ag, 6000 Frankfurt | Herbicidal agents based on phenoxycarboxylic acid derivatives |
DE2355115A1 (en) * | 1972-11-07 | 1974-05-09 | Erba Carlo Spa | SUBSTITUTED PHENOXYALCANCARBON ACIDS, FUNCTIONAL DERIVATIVES AND SALT THEREOF, AND THE PROCESS FOR THEIR PRODUCTION |
-
1975
- 1975-09-17 CH CH1204875A patent/CH609024A5/en not_active IP Right Cessation
- 1975-09-22 IE IE207075A patent/IE42609B1/en unknown
- 1975-09-23 CA CA236,205A patent/CA1064504A/en not_active Expired
- 1975-09-27 DE DE19752560602 patent/DE2560602C2/en not_active Expired
- 1975-09-27 DE DE19752543179 patent/DE2543179A1/en not_active Withdrawn
- 1975-09-29 NL NL7511452A patent/NL176776C/en not_active IP Right Cessation
- 1975-09-29 DK DK437075A patent/DK146336C/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK437075A (en) | 1976-03-31 |
DE2560602C2 (en) | 1986-08-28 |
DK146336B (en) | 1983-09-12 |
CA1064504A (en) | 1979-10-16 |
DE2543179A1 (en) | 1976-04-15 |
IE42609L (en) | 1976-03-30 |
NL7511452A (en) | 1976-04-01 |
IE42609B1 (en) | 1980-09-10 |
NL176776B (en) | 1985-01-02 |
NL176776C (en) | 1985-06-03 |
DK146336C (en) | 1984-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |