NL176776C - METHOD FOR PREPARING MEDICINES WITH BLOOD PLATE AGGREGATION INHIBITING AND SERUM LIPID RESP. SERUM CHOLESTEROL MIRROR LOWERING ACTIVITY, AND METHOD FOR PREPARING APPROPRIATE MEDICINE COMPOUNDS. - Google Patents

METHOD FOR PREPARING MEDICINES WITH BLOOD PLATE AGGREGATION INHIBITING AND SERUM LIPID RESP. SERUM CHOLESTEROL MIRROR LOWERING ACTIVITY, AND METHOD FOR PREPARING APPROPRIATE MEDICINE COMPOUNDS.

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Publication number
NL176776C
NL176776C NL7511452A NL7511452A NL176776C NL 176776 C NL176776 C NL 176776C NL 7511452 A NL7511452 A NL 7511452A NL 7511452 A NL7511452 A NL 7511452A NL 176776 C NL176776 C NL 176776C
Authority
NL
Netherlands
Prior art keywords
preparing
serum
resp
lowering activity
aggregation inhibiting
Prior art date
Application number
NL7511452A
Other languages
Dutch (nl)
Other versions
NL7511452A (en
NL176776B (en
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4238774A external-priority patent/GB1519147A/en
Priority claimed from FR7502307A external-priority patent/FR2258846A1/en
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of NL7511452A publication Critical patent/NL7511452A/en
Priority to NLAANVRAGE8302612,A priority Critical patent/NL178316C/en
Priority to NLAANVRAGE8302611,A priority patent/NL178418C/en
Priority to NLAANVRAGE8302613,A priority patent/NL178964C/en
Publication of NL176776B publication Critical patent/NL176776B/en
Application granted granted Critical
Publication of NL176776C publication Critical patent/NL176776C/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
    • C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7511452A 1974-09-30 1975-09-29 METHOD FOR PREPARING MEDICINES WITH BLOOD PLATE AGGREGATION INHIBITING AND SERUM LIPID RESP. SERUM CHOLESTEROL MIRROR LOWERING ACTIVITY, AND METHOD FOR PREPARING APPROPRIATE MEDICINE COMPOUNDS. NL176776C (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
NLAANVRAGE8302612,A NL178316C (en) 1974-09-30 1983-07-21 METHOD FOR PREPARING MEDICINES WITH GOOD INFLUENCE ON BLOOD CIRCUMSTICS AND METHOD FOR PREPARING MEDICINAL COMPOSITIONS SUITABLE THEREFOR.
NLAANVRAGE8302611,A NL178418C (en) 1974-09-30 1983-07-21 METHOD FOR PREPARING PHENYL ETHERS CONTAINING MEDICINES WITH FAVORABLE INFLUENCE ON BLOOD CIRCULATION AND SUITABLE COMPOUNDS
NLAANVRAGE8302613,A NL178964C (en) 1974-09-30 1983-07-21 METHOD FOR PREPARING MEDICINES WITH GOOD INFLUENCE ON BLOOD CIRCUMSTICS AND METHOD FOR PREPARING MEDICINAL COMPOSITIONS SUITABLE THEREFOR.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB4238774A GB1519147A (en) 1974-09-30 1974-09-30 Sulphur and oxygen-containing diaryl compounds
GB158775 1975-01-14
FR7502307A FR2258846A1 (en) 1974-01-25 1975-01-24 Bis((N-hydroxy alkyl)-amino alkyl thio)alkane and derivs - as agents preventing blood platelet aggregation

Publications (3)

Publication Number Publication Date
NL7511452A NL7511452A (en) 1976-04-01
NL176776B NL176776B (en) 1985-01-02
NL176776C true NL176776C (en) 1985-06-03

Family

ID=27250408

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7511452A NL176776C (en) 1974-09-30 1975-09-29 METHOD FOR PREPARING MEDICINES WITH BLOOD PLATE AGGREGATION INHIBITING AND SERUM LIPID RESP. SERUM CHOLESTEROL MIRROR LOWERING ACTIVITY, AND METHOD FOR PREPARING APPROPRIATE MEDICINE COMPOUNDS.

Country Status (6)

Country Link
CA (1) CA1064504A (en)
CH (1) CH609024A5 (en)
DE (2) DE2543179A1 (en)
DK (1) DK146336C (en)
IE (1) IE42609B1 (en)
NL (1) NL176776C (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1571829A (en) 1976-04-06 1980-07-23 Lafon Labor Sulphur-containing diaryl compounds and oxygen-containing diaryl compounds
DK0580550T3 (en) * 1992-07-21 1998-02-02 Ciba Geigy Ag Oxamic acid derivatives as hypercholesterolemic agents
JP4045099B2 (en) 1999-11-01 2008-02-13 大正製薬株式会社 20-HETE producing enzyme inhibitor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1935344U (en) 1965-11-09 1966-03-24 Karosserie Migoe Chr H Mittelg DOUBLE WALL FOR VEHICLE BODIES, ESPECIALLY FOR REFRIGERATION AND THERMAL CARRIAGE OD. THE EQUAL, WHERE THE SPACE BETWEEN TWO WALLS IS FILLED WITH INSULATING MATERIAL.
DE1668896C3 (en) 1968-01-11 1974-08-29 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Phenoxyalkanecarboxylic acids, their salts and esters, and processes for the preparation of these compounds
US3721703A (en) * 1968-01-11 1973-03-20 Hoechst Ag Phenoxyalkane-carboxylic acids,salts and esters thereof
BE786644A (en) * 1971-07-23 1973-01-24 Hoechst Ag PHENOXY-4 PHENOXY-ALKANE-CARBOXYL ACID DERIVATIVES THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FI55986C (en) * 1972-05-10 1979-11-12 Ciba Geigy Ag FOER ANVAENDNING SOM SKADEDJURS BEKAEMPNINGSMEDEL AVSEDDA SUBSTITUERADE FENYLDERIVAT
DE2223894C3 (en) * 1972-05-17 1981-07-23 Hoechst Ag, 6000 Frankfurt Herbicidal agents based on phenoxycarboxylic acid derivatives
DE2355115A1 (en) * 1972-11-07 1974-05-09 Erba Carlo Spa SUBSTITUTED PHENOXYALCANCARBON ACIDS, FUNCTIONAL DERIVATIVES AND SALT THEREOF, AND THE PROCESS FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
DK146336B (en) 1983-09-12
CA1064504A (en) 1979-10-16
NL7511452A (en) 1976-04-01
IE42609B1 (en) 1980-09-10
DK146336C (en) 1984-02-20
NL176776B (en) 1985-01-02
IE42609L (en) 1976-03-30
DE2560602C2 (en) 1986-08-28
CH609024A5 (en) 1979-02-15
DK437075A (en) 1976-03-31
DE2543179A1 (en) 1976-04-15

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