FI112667B - Uusi sieniproteaasi - Google Patents

Uusi sieniproteaasi Download PDF

Info

Publication number
FI112667B
FI112667B FI931634A FI931634A FI112667B FI 112667 B FI112667 B FI 112667B FI 931634 A FI931634 A FI 931634A FI 931634 A FI931634 A FI 931634A FI 112667 B FI112667 B FI 112667B
Authority
FI
Finland
Prior art keywords
dna
sequence
ala
gene
ser
Prior art date
Application number
FI931634A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI931634A0 (fi
FI931634A (fi
Inventor
Frank Buxton
Jacob Visser
Albert Hinnen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939305097A external-priority patent/GB9305097D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of FI931634A0 publication Critical patent/FI931634A0/fi
Publication of FI931634A publication Critical patent/FI931634A/fi
Application granted granted Critical
Publication of FI112667B publication Critical patent/FI112667B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI931634A 1992-04-15 1993-04-08 Uusi sieniproteaasi FI112667B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP92810281 1992-04-15
EP92810281 1992-04-15
GB9305097 1993-03-12
GB939305097A GB9305097D0 (en) 1993-03-12 1993-03-12 Noval fungal protease

Publications (3)

Publication Number Publication Date
FI931634A0 FI931634A0 (fi) 1993-04-08
FI931634A FI931634A (fi) 1993-10-16
FI112667B true FI112667B (fi) 2003-12-31

Family

ID=26132501

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931634A FI112667B (fi) 1992-04-15 1993-04-08 Uusi sieniproteaasi

Country Status (17)

Country Link
EP (1) EP0574347B1 (zh)
JP (2) JP3424840B2 (zh)
KR (1) KR100270644B1 (zh)
AT (1) ATE252156T1 (zh)
AU (1) AU663173B2 (zh)
CA (1) CA2093950C (zh)
CY (1) CY2507B1 (zh)
DE (1) DE69333249T2 (zh)
DK (1) DK0574347T3 (zh)
ES (1) ES2208637T3 (zh)
FI (1) FI112667B (zh)
HU (1) HU219809B (zh)
IL (2) IL170763A (zh)
MX (1) MX9302202A (zh)
NO (1) NO315379B1 (zh)
NZ (1) NZ247397A (zh)
PT (1) PT574347E (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821350A (en) * 1995-11-01 1998-10-13 Nexia Biotechnologies, Inc. Aspergillus niger beta-galactosidase gene
AU1092897A (en) * 1995-12-15 1997-07-14 Novo Nordisk A/S A funguns wherein the area, pepc and/or pepe genes have been inactivated
EP0894126B1 (en) * 1996-03-27 2006-02-01 Novozymes A/S Alkaline protease deficient filamentous fungi
EP0907744A1 (en) * 1996-06-05 1999-04-14 Gist-Brocades B.V. Fungal metallo protease genes
JPH1016992A (ja) * 1996-07-04 1998-01-20 Toagosei Co Ltd 接着剤用容器
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
ATE469223T1 (de) 2000-03-14 2010-06-15 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
DK1941025T3 (da) 2005-10-17 2011-09-26 Novozymes As Brug af svampemutanter til ekspression af antistoffer
CN101889020B (zh) 2007-12-06 2014-01-22 诺维信公司 真菌PepC抑制剂
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
MD4186C1 (ro) * 2012-02-20 2013-06-30 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Tulpină de fungi Fusarium gibbosum - producătoare de proteaze acide şi neutre, xilanaze şi b-glucozidaze
CA2916905A1 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
DK3036324T3 (en) * 2013-08-23 2019-04-01 Novozymes As Regulated PepC expression
EP3172333B1 (en) 2014-07-21 2020-05-13 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi

Also Published As

Publication number Publication date
CA2093950A1 (en) 1993-10-16
JP2003235591A (ja) 2003-08-26
HU9301087D0 (en) 1993-06-28
AU663173B2 (en) 1995-09-28
DE69333249D1 (de) 2003-11-20
CY2507B1 (en) 2005-12-23
AU3695993A (en) 1993-10-21
KR930021783A (ko) 1993-11-23
FI931634A0 (fi) 1993-04-08
JP3424840B2 (ja) 2003-07-07
JPH0646863A (ja) 1994-02-22
PT574347E (pt) 2004-02-27
DE69333249T2 (de) 2004-07-29
MX9302202A (es) 1994-04-29
ES2208637T3 (es) 2004-06-16
CA2093950C (en) 2006-05-09
IL105383A0 (en) 1993-08-18
EP0574347B1 (en) 2003-10-15
NO315379B1 (no) 2003-08-25
EP0574347A2 (en) 1993-12-15
HUT67800A (en) 1995-05-29
FI931634A (fi) 1993-10-16
JP3636455B2 (ja) 2005-04-06
IL170763A (en) 2007-10-31
HU219809B (hu) 2001-08-28
NO931368D0 (no) 1993-04-14
DK0574347T3 (da) 2004-01-26
KR100270644B1 (ko) 2000-11-01
EP0574347A3 (zh) 1994-04-13
NZ247397A (en) 1995-08-28
ATE252156T1 (de) 2003-11-15
NO931368L (no) 1993-10-18

Similar Documents

Publication Publication Date Title
FI112667B (fi) Uusi sieniproteaasi
IE20030875A1 (en) Selection marker gene free recombinant strains: a method for obtaining them and the use of these strains
JP2633885B2 (ja) 新規な発現系
CA2134863C (en) Aspergillus niger aspartic protease
US5846802A (en) Fungal Protease
IL91111A (en) Recombinant AND molecules that encode pectin for lysates and expression systems
JP3576549B2 (ja) 真核生物発現系
EP0439997B1 (en) Novel fungal expression system
JPH06343471A (ja) ポリペプチドの製造方法
WO2001066693A1 (en) Compositions and methods for producing high yields of heterologous polypeptides in a pichia cell

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: NOVARTIS AG

MA Patent expired