FI111462B - Menetelmä motiliinityyppisten polypeptidien valmistamiseksi, joilla on ruoansulatuskanavan motiliteettia stimuloivaa aktiivisuutta - Google Patents

Menetelmä motiliinityyppisten polypeptidien valmistamiseksi, joilla on ruoansulatuskanavan motiliteettia stimuloivaa aktiivisuutta Download PDF

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Publication number
FI111462B
FI111462B FI943651A FI943651A FI111462B FI 111462 B FI111462 B FI 111462B FI 943651 A FI943651 A FI 943651A FI 943651 A FI943651 A FI 943651A FI 111462 B FI111462 B FI 111462B
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FI
Finland
Prior art keywords
leu
glu
gln
phe
thr
Prior art date
Application number
FI943651A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI943651A0 (fi
FI943651A (fi
Inventor
Mark J Macielag
Ramalinga Dharanipragada
James R Florance
Mary Sue Marvin
Alphonse Galdes
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Baxter Int filed Critical Baxter Int
Publication of FI943651A0 publication Critical patent/FI943651A0/fi
Publication of FI943651A publication Critical patent/FI943651A/fi
Application granted granted Critical
Publication of FI111462B publication Critical patent/FI111462B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/63—Motilins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
FI943651A 1993-08-06 1994-08-05 Menetelmä motiliinityyppisten polypeptidien valmistamiseksi, joilla on ruoansulatuskanavan motiliteettia stimuloivaa aktiivisuutta FI111462B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/103,490 US5422341A (en) 1993-08-06 1993-08-06 Motilin-like polypeptides with gastrointestinal motor stimulating activity
US10349093 1993-08-06

Publications (3)

Publication Number Publication Date
FI943651A0 FI943651A0 (fi) 1994-08-05
FI943651A FI943651A (fi) 1995-02-07
FI111462B true FI111462B (fi) 2003-07-31

Family

ID=22295474

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943651A FI111462B (fi) 1993-08-06 1994-08-05 Menetelmä motiliinityyppisten polypeptidien valmistamiseksi, joilla on ruoansulatuskanavan motiliteettia stimuloivaa aktiivisuutta

Country Status (15)

Country Link
US (1) US5422341A (zh)
EP (1) EP0646601B1 (zh)
JP (1) JP2949129B2 (zh)
KR (1) KR100360975B1 (zh)
CN (1) CN1054857C (zh)
AT (1) ATE194627T1 (zh)
AU (1) AU677324B2 (zh)
CA (1) CA2127330C (zh)
DE (1) DE69425212T2 (zh)
DK (1) DK0646601T3 (zh)
ES (1) ES2152293T3 (zh)
FI (1) FI111462B (zh)
NO (1) NO312299B1 (zh)
TW (1) TW434261B (zh)
ZA (1) ZA945436B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5734012A (en) * 1996-05-16 1998-03-31 Ohmeda Pharmaceutical Products Division Inc. Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity
IL140993A0 (en) * 2000-05-15 2002-02-10 Bayer Ag Trypsin substrate and diagnostic device, and method of using same
US20050009205A1 (en) * 2003-07-11 2005-01-13 Ye Fang Fluorescent ligands for GPCR arrays
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
US20060293243A1 (en) * 2005-06-17 2006-12-28 Navneet Puri Stable, buffered, pharmaceutical compositions including motilin-like peptides
US20060287243A1 (en) * 2005-06-17 2006-12-21 Navneet Puri Stable pharmaceutical compositions including motilin-like peptides
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
AU2010279076B2 (en) * 2009-07-29 2014-09-25 Daiichi Sankyo Company,Limited Motilin-like peptide compound having transmucosal absorbability imparted thereto
CN107383169A (zh) * 2017-04-24 2017-11-24 青岛大学 一种具有胃肠运动刺激活性的多肽

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2753274B2 (ja) * 1988-08-24 1998-05-18 株式会社三和化学研究所 モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド
EP0378078A1 (en) * 1989-01-06 1990-07-18 Sanwa Kagaku Kenkyusho Co., Ltd. Motilin-like polypeptide and use thereof
JPH02311495A (ja) * 1989-05-24 1990-12-27 Sanwa Kagaku Kenkyusho Co Ltd モチリン様活性を有するポリペプチド及びその用途
JPH04364131A (ja) * 1991-04-03 1992-12-16 Sanwa Kagaku Kenkyusho Co Ltd 易吸収性モチリン製剤

Also Published As

Publication number Publication date
CN1054857C (zh) 2000-07-26
DK0646601T3 (da) 2000-09-18
ATE194627T1 (de) 2000-07-15
CA2127330A1 (en) 1995-02-07
JP2949129B2 (ja) 1999-09-13
NO942690D0 (no) 1994-07-18
US5422341A (en) 1995-06-06
FI943651A0 (fi) 1994-08-05
CN1119650A (zh) 1996-04-03
JPH0770178A (ja) 1995-03-14
EP0646601A1 (en) 1995-04-05
FI943651A (fi) 1995-02-07
AU677324B2 (en) 1997-04-17
ES2152293T3 (es) 2001-02-01
DE69425212T2 (de) 2001-03-08
CA2127330C (en) 1998-07-14
ZA945436B (en) 1995-04-04
KR100360975B1 (ko) 2003-01-24
AU6596794A (en) 1995-02-16
KR950005320A (ko) 1995-03-20
TW434261B (en) 2001-05-16
DE69425212D1 (de) 2000-08-17
NO312299B1 (no) 2002-04-22
NO942690L (no) 1995-02-07
EP0646601B1 (en) 2000-07-12

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