DK0646601T3 - Motilin-lignende polypeptider med gastrointestinal motorisk stimulerende aktivitet - Google Patents

Motilin-lignende polypeptider med gastrointestinal motorisk stimulerende aktivitet

Info

Publication number
DK0646601T3
DK0646601T3 DK94305707T DK94305707T DK0646601T3 DK 0646601 T3 DK0646601 T3 DK 0646601T3 DK 94305707 T DK94305707 T DK 94305707T DK 94305707 T DK94305707 T DK 94305707T DK 0646601 T3 DK0646601 T3 DK 0646601T3
Authority
DK
Denmark
Prior art keywords
glu
leu
lys
gln
arg
Prior art date
Application number
DK94305707T
Other languages
English (en)
Inventor
Mark J Macielag
Ramalinga Dharanipragada
James R Florance
Mary Sue Marvin
Alphonse Galdes
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Application granted granted Critical
Publication of DK0646601T3 publication Critical patent/DK0646601T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/63—Motilins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK94305707T 1993-08-06 1994-08-01 Motilin-lignende polypeptider med gastrointestinal motorisk stimulerende aktivitet DK0646601T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/103,490 US5422341A (en) 1993-08-06 1993-08-06 Motilin-like polypeptides with gastrointestinal motor stimulating activity

Publications (1)

Publication Number Publication Date
DK0646601T3 true DK0646601T3 (da) 2000-09-18

Family

ID=22295474

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94305707T DK0646601T3 (da) 1993-08-06 1994-08-01 Motilin-lignende polypeptider med gastrointestinal motorisk stimulerende aktivitet

Country Status (15)

Country Link
US (1) US5422341A (da)
EP (1) EP0646601B1 (da)
JP (1) JP2949129B2 (da)
KR (1) KR100360975B1 (da)
CN (1) CN1054857C (da)
AT (1) ATE194627T1 (da)
AU (1) AU677324B2 (da)
CA (1) CA2127330C (da)
DE (1) DE69425212T2 (da)
DK (1) DK0646601T3 (da)
ES (1) ES2152293T3 (da)
FI (1) FI111462B (da)
NO (1) NO312299B1 (da)
TW (1) TW434261B (da)
ZA (1) ZA945436B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5734012A (en) * 1996-05-16 1998-03-31 Ohmeda Pharmaceutical Products Division Inc. Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity
IL140993A0 (en) * 2000-05-15 2002-02-10 Bayer Ag Trypsin substrate and diagnostic device, and method of using same
US20050009205A1 (en) * 2003-07-11 2005-01-13 Ye Fang Fluorescent ligands for GPCR arrays
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
US20060287243A1 (en) * 2005-06-17 2006-12-21 Navneet Puri Stable pharmaceutical compositions including motilin-like peptides
US20060293243A1 (en) * 2005-06-17 2006-12-28 Navneet Puri Stable, buffered, pharmaceutical compositions including motilin-like peptides
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
MX2012001193A (es) 2009-07-29 2012-03-14 Daiichi Sankyo Co Ltd Compuesto peptidico similar a motilina con capacidad de absorcion transmucosa impartida al mismo.
CN107383169A (zh) * 2017-04-24 2017-11-24 青岛大学 一种具有胃肠运动刺激活性的多肽

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2753274B2 (ja) * 1988-08-24 1998-05-18 株式会社三和化学研究所 モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド
EP0378078A1 (en) * 1989-01-06 1990-07-18 Sanwa Kagaku Kenkyusho Co., Ltd. Motilin-like polypeptide and use thereof
JPH02311495A (ja) * 1989-05-24 1990-12-27 Sanwa Kagaku Kenkyusho Co Ltd モチリン様活性を有するポリペプチド及びその用途
JPH04364131A (ja) * 1991-04-03 1992-12-16 Sanwa Kagaku Kenkyusho Co Ltd 易吸収性モチリン製剤

Also Published As

Publication number Publication date
US5422341A (en) 1995-06-06
NO312299B1 (no) 2002-04-22
JP2949129B2 (ja) 1999-09-13
FI943651A0 (fi) 1994-08-05
AU6596794A (en) 1995-02-16
JPH0770178A (ja) 1995-03-14
KR950005320A (ko) 1995-03-20
ZA945436B (en) 1995-04-04
KR100360975B1 (ko) 2003-01-24
CN1054857C (zh) 2000-07-26
EP0646601A1 (en) 1995-04-05
AU677324B2 (en) 1997-04-17
CN1119650A (zh) 1996-04-03
CA2127330C (en) 1998-07-14
NO942690D0 (no) 1994-07-18
NO942690L (no) 1995-02-07
DE69425212D1 (de) 2000-08-17
DE69425212T2 (de) 2001-03-08
ES2152293T3 (es) 2001-02-01
TW434261B (en) 2001-05-16
ATE194627T1 (de) 2000-07-15
FI943651A (fi) 1995-02-07
FI111462B (fi) 2003-07-31
CA2127330A1 (en) 1995-02-07
EP0646601B1 (en) 2000-07-12

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