ES8504700A1 - Un procedimiento para la preparacion de cefoperazona sodica altamente cristalina - Google Patents

Un procedimiento para la preparacion de cefoperazona sodica altamente cristalina

Info

Publication number
ES8504700A1
ES8504700A1 ES529485A ES529485A ES8504700A1 ES 8504700 A1 ES8504700 A1 ES 8504700A1 ES 529485 A ES529485 A ES 529485A ES 529485 A ES529485 A ES 529485A ES 8504700 A1 ES8504700 A1 ES 8504700A1
Authority
ES
Spain
Prior art keywords
acetone
water
cefoperazone
highly crystalline
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529485A
Other languages
English (en)
Spanish (es)
Other versions
ES529485A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8504700A1 publication Critical patent/ES8504700A1/es
Publication of ES529485A0 publication Critical patent/ES529485A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES529485A 1983-02-07 1984-02-06 Un procedimiento para la preparacion de cefoperazona sodica altamente cristalina Granted ES529485A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/464,223 US4456753A (en) 1983-02-07 1983-02-07 Process for the manufacture of highly crystalline sodium cefoperazone

Publications (2)

Publication Number Publication Date
ES8504700A1 true ES8504700A1 (es) 1985-05-01
ES529485A0 ES529485A0 (es) 1985-05-01

Family

ID=23843028

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529485A Granted ES529485A0 (es) 1983-02-07 1984-02-06 Un procedimiento para la preparacion de cefoperazona sodica altamente cristalina

Country Status (22)

Country Link
US (1) US4456753A (https=)
EP (1) EP0118196B1 (https=)
JP (1) JPH0643429B2 (https=)
KR (1) KR870001071B1 (https=)
AU (1) AU541675B2 (https=)
CA (1) CA1190220A (https=)
DE (1) DE3461802D1 (https=)
DK (1) DK152757C (https=)
ES (1) ES529485A0 (https=)
FI (1) FI75571C (https=)
GR (1) GR81694B (https=)
HK (1) HK99687A (https=)
HU (1) HU190544B (https=)
IE (1) IE56752B1 (https=)
IL (1) IL70872A (https=)
NZ (1) NZ207038A (https=)
PH (1) PH19052A (https=)
PL (1) PL146540B1 (https=)
PT (1) PT78058B (https=)
SG (1) SG70087G (https=)
YU (1) YU43562B (https=)
ZA (1) ZA84853B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20002029B (en) 1995-07-17 2000-04-10 Warner Lambert Company Us (54) Crystalline [R-(R*,R*,]–2-(4-Fluorophenyl)-Beta,Delta-Dihydroxy-5-(1-Methyl-Ethyl)-3-Phenyl–4-{Phenylamino) Carbonyl} - 1H - Pyrrole - 1 - Heptanoic Acid Hemi Calcium Salt (Atorvastatin)
WO1999024441A1 (en) * 1997-11-10 1999-05-20 Dsm N.V. Crystallization of beta-lactam compounds
MXPA01009808A (es) * 1999-04-01 2002-04-24 Dsm Nv Aglomerados por cristalizacion.
IT1318467B1 (it) * 2000-04-14 2003-08-25 Antibioticos Spa Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'.
JP2009517335A (ja) * 2005-09-21 2009-04-30 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 次亜ハロゲン酸組成物を用いた尿路感染（ｕｔｉ）を含む細菌・菌類感染の防止及び処理のためのシステム及び方法
CN101863907B (zh) * 2010-07-07 2012-05-23 福建省福抗药业股份有限公司 一种头孢哌酮钠的结晶方法
CN104470933A (zh) * 2012-07-17 2015-03-25 中化帝斯曼制药有限公司荷兰公司 头孢哌酮钠新晶型
CN103951679B (zh) * 2014-04-29 2016-04-27 悦康药业集团有限公司 一种头孢哌酮钠化合物及其药物组合物
CN104327099A (zh) * 2014-09-29 2015-02-04 联合康兴（北京）医药科技有限公司 头孢哌酮钠化合物实体及组合物和用途
CN105440057B (zh) * 2015-11-25 2017-10-17 华北制药河北华民药业有限责任公司 一种制备头孢哌酮钠的方法
CN112442048B (zh) * 2020-11-10 2022-04-08 华北制药河北华民药业有限责任公司 一种头孢匹胺钠的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
GB1508071A (en) * 1976-01-19 1978-04-19 Toyama Chemical Co Ltd Cephalosporins and process for producing the same
DE2600880C2 (de) * 1976-01-12 1984-09-13 Toyama Chemical Co. Ltd., Tokio / Tokyo Cephalosporinverbindungen
IL53427A0 (en) * 1976-11-24 1978-01-31 Lilly Co Eli Method of preparing a rapidly dissolving powder of sterile crystalline cefozolin sodium for parenteral administration

Also Published As

Publication number Publication date
IE840273L (en) 1984-08-07
FI75571B (fi) 1988-03-31
DK152757B (da) 1988-05-09
DE3461802D1 (en) 1987-02-05
KR870001071B1 (ko) 1987-05-27
PL246090A1 (en) 1985-02-13
ES529485A0 (es) 1985-05-01
PH19052A (en) 1985-12-11
AU2420984A (en) 1984-08-16
PL146540B1 (en) 1989-02-28
EP0118196A1 (en) 1984-09-12
US4456753A (en) 1984-06-26
NZ207038A (en) 1986-05-09
DK51784D0 (da) 1984-02-06
HU190544B (en) 1986-09-29
EP0118196B1 (en) 1986-12-30
JPH0643429B2 (ja) 1994-06-08
JPS59148789A (ja) 1984-08-25
IL70872A0 (en) 1984-05-31
YU20684A (en) 1986-06-30
FI840475A7 (fi) 1984-08-08
KR840007730A (ko) 1984-12-10
PT78058B (en) 1986-06-02
FI840475A0 (fi) 1984-02-06
PT78058A (en) 1984-03-01
IL70872A (en) 1987-08-31
FI75571C (fi) 1988-07-11
YU43562B (en) 1989-08-31
HK99687A (en) 1987-12-31
IE56752B1 (en) 1991-12-04
GR81694B (https=) 1984-12-12
HUT34208A (en) 1985-02-28
ZA84853B (en) 1985-09-25
SG70087G (en) 1988-02-19
DK51784A (da) 1984-08-08
DK152757C (da) 1988-09-26
AU541675B2 (en) 1985-01-17
CA1190220A (en) 1985-07-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050209