IT1318467B1 - Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'. - Google Patents

Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'.

Info

Publication number
IT1318467B1
IT1318467B1 IT2000MI000837A ITMI20000837A IT1318467B1 IT 1318467 B1 IT1318467 B1 IT 1318467B1 IT 2000MI000837 A IT2000MI000837 A IT 2000MI000837A IT MI20000837 A ITMI20000837 A IT MI20000837A IT 1318467 B1 IT1318467 B1 IT 1318467B1
Authority
IT
Italy
Prior art keywords
cefoperazone
sode
synthesis process
highly
crystallinity
Prior art date
Application number
IT2000MI000837A
Other languages
English (en)
Inventor
Walter Cabri
Giovanni Pozzi
Paolo Ghetti
Domenico Vergani
Roberto Strigaro
Original Assignee
Antibioticos Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos Spa filed Critical Antibioticos Spa
Publication of ITMI20000837A0 publication Critical patent/ITMI20000837A0/it
Priority to IT2000MI000837A priority Critical patent/IT1318467B1/it
Priority to PT01940312T priority patent/PT1272495E/pt
Priority to PCT/EP2001/004074 priority patent/WO2001079210A2/en
Priority to DE60104103T priority patent/DE60104103T2/de
Priority to DK01940312T priority patent/DK1272495T3/da
Priority to EP01940312A priority patent/EP1272495B1/en
Priority to AT01940312T priority patent/ATE270296T1/de
Priority to AU2001273933A priority patent/AU2001273933A1/en
Priority to TR2004/01624T priority patent/TR200401624T4/xx
Priority to ES01940312T priority patent/ES2223871T3/es
Priority to US10/240,758 priority patent/US20040030127A1/en
Priority to JP2001576809A priority patent/JP2003531147A/ja
Priority to KR1020027013751A priority patent/KR20030005281A/ko
Publication of ITMI20000837A1 publication Critical patent/ITMI20000837A1/it
Application granted granted Critical
Publication of IT1318467B1 publication Critical patent/IT1318467B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
IT2000MI000837A 2000-04-14 2000-04-14 Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'. IT1318467B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT2000MI000837A IT1318467B1 (it) 2000-04-14 2000-04-14 Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'.
AT01940312T ATE270296T1 (de) 2000-04-14 2001-04-10 Verfahren zur herstellung von hochkristallinem natrium cefoperazon
TR2004/01624T TR200401624T4 (tr) 2000-04-14 2001-04-10 Yüksek derecede kristalimsi sodyum Cefoperazone'un hazırlanması için bir işlem.
DE60104103T DE60104103T2 (de) 2000-04-14 2001-04-10 Verfahren zur herstellung von hochkristallinem natrium cefoperazon
DK01940312T DK1272495T3 (da) 2000-04-14 2001-04-10 Fremgangsmåde til fremstilling af stærkt krystallinsk natriumcefoperazon
EP01940312A EP1272495B1 (en) 2000-04-14 2001-04-10 A process for the preparation of highly crystalline sodium cefoperazone
PT01940312T PT1272495E (pt) 2000-04-14 2001-04-10 Processo para a preparacao de cefoperazona de sodio altamente cristalina
AU2001273933A AU2001273933A1 (en) 2000-04-14 2001-04-10 A process for the preparation of highly crystalline sodium cefoperazone
PCT/EP2001/004074 WO2001079210A2 (en) 2000-04-14 2001-04-10 A process for the preparation of highly crystalline sodium cefoperazone
ES01940312T ES2223871T3 (es) 2000-04-14 2001-04-10 Procedimiento de preparacion de cefoperazona sodica altamente cristalina.
US10/240,758 US20040030127A1 (en) 2000-04-14 2001-04-10 Process for the preparation of highly crystalline sodium cefoperazone
JP2001576809A JP2003531147A (ja) 2000-04-14 2001-04-10 高結晶質セフォペラゾンナトリウムを調製するための方法
KR1020027013751A KR20030005281A (ko) 2000-04-14 2001-04-10 고결정형 소듐 세포페라존의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000837A IT1318467B1 (it) 2000-04-14 2000-04-14 Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'.

Publications (3)

Publication Number Publication Date
ITMI20000837A0 ITMI20000837A0 (it) 2000-04-14
ITMI20000837A1 ITMI20000837A1 (it) 2001-10-14
IT1318467B1 true IT1318467B1 (it) 2003-08-25

Family

ID=11444863

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI000837A IT1318467B1 (it) 2000-04-14 2000-04-14 Processo per la sintesi di cefoperazone sodico ad elevatacristallinita'.

Country Status (13)

Country Link
US (1) US20040030127A1 (it)
EP (1) EP1272495B1 (it)
JP (1) JP2003531147A (it)
KR (1) KR20030005281A (it)
AT (1) ATE270296T1 (it)
AU (1) AU2001273933A1 (it)
DE (1) DE60104103T2 (it)
DK (1) DK1272495T3 (it)
ES (1) ES2223871T3 (it)
IT (1) IT1318467B1 (it)
PT (1) PT1272495E (it)
TR (1) TR200401624T4 (it)
WO (1) WO2001079210A2 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040092735A1 (en) * 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium
KR100608056B1 (ko) 2004-06-05 2006-08-02 삼성전자주식회사 멀티미디어 컨텐츠 재생 장치, 재생 방법, 생성 장치,생성 방법, 및 그 멀티미디어 컨텐츠를 저장한 저장 매체
CN101863907B (zh) * 2010-07-07 2012-05-23 福建省福抗药业股份有限公司 一种头孢哌酮钠的结晶方法
CN104470933A (zh) * 2012-07-17 2015-03-25 中化帝斯曼制药有限公司荷兰公司 头孢哌酮钠新晶型
CN103951679B (zh) * 2014-04-29 2016-04-27 悦康药业集团有限公司 一种头孢哌酮钠化合物及其药物组合物
CN104327099A (zh) * 2014-09-29 2015-02-04 联合康兴（北京）医药科技有限公司 头孢哌酮钠化合物实体及组合物和用途
CN112279868B (zh) * 2020-09-24 2021-10-15 华北制药河北华民药业有限责任公司 一种头孢哌酮钠的纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1508071A (en) * 1976-01-19 1978-04-19 Toyama Chemical Co Ltd Cephalosporins and process for producing the same
US4456753A (en) * 1983-02-07 1984-06-26 Pfizer Inc. Process for the manufacture of highly crystalline sodium cefoperazone

Also Published As

Publication number Publication date
ITMI20000837A1 (it) 2001-10-14
PT1272495E (pt) 2004-09-30
EP1272495B1 (en) 2004-06-30
ES2223871T3 (es) 2005-03-01
JP2003531147A (ja) 2003-10-21
DK1272495T3 (da) 2004-11-22
DE60104103T2 (de) 2004-11-11
DE60104103D1 (de) 2004-08-05
WO2001079210A2 (en) 2001-10-25
TR200401624T4 (tr) 2004-08-23
AU2001273933A1 (en) 2001-10-30
ITMI20000837A0 (it) 2000-04-14
EP1272495A2 (en) 2003-01-08
US20040030127A1 (en) 2004-02-12
WO2001079210A3 (en) 2002-02-21
KR20030005281A (ko) 2003-01-17
ATE270296T1 (de) 2004-07-15

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