ES8304577A1 - "procedimiento para la preparacion de nuevas cefalosporinas". - Google Patents

"procedimiento para la preparacion de nuevas cefalosporinas".

Info

Publication number
ES8304577A1
ES8304577A1 ES512524A ES512524A ES8304577A1 ES 8304577 A1 ES8304577 A1 ES 8304577A1 ES 512524 A ES512524 A ES 512524A ES 512524 A ES512524 A ES 512524A ES 8304577 A1 ES8304577 A1 ES 8304577A1
Authority
ES
Spain
Prior art keywords
hydrogen
image
aminocarbonylamino
methylsulfinyl
aminosulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512524A
Other languages
English (en)
Other versions
ES512524A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES512524A0 publication Critical patent/ES512524A0/es
Publication of ES8304577A1 publication Critical patent/ES8304577A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

_(PROCEDIMIENTO PARA LA PREPARACION DE CEFALOSPORINAS . SE HACE REACCIONAR EL COMPUESTO DE FORMULA GENERAL (II) CON HET-S-M. SE EMPLEA UN DISOLVENTE FUERTEMENTE POLAR TAL COMO AGUA EN CUYO CASO EL PH DE LA SOLUCION SE MANTIENE ENTRE 2 Y 10 AJUSTANDOSE EL VALOR DEL MISMO MEDIANTE UN TAMPON TAL COMO FOSFATO SODICO. NORMALMENTE LA TEMPERATURA DE REACCION OSCILA ENTRE 0 C Y 100 C DURANTE EL TIEMPO DE UNAS HORAS. SE OBTIENE EL COMPUESTO (I). ACTIVIDAD ANTIBIOTICA.
ES512524A 1980-10-11 1982-05-25 "procedimiento para la preparacion de nuevas cefalosporinas". Expired ES8304577A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803038501 DE3038501A1 (de) 1980-10-11 1980-10-11 Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES512524A0 ES512524A0 (es) 1983-03-01
ES8304577A1 true ES8304577A1 (es) 1983-03-01

Family

ID=6114191

Family Applications (3)

Application Number Title Priority Date Filing Date
ES505781A Granted ES505781A0 (es) 1980-10-11 1981-09-25 Procedimiento para la preparacion de nuevas cefalosporinas
ES512524A Expired ES8304577A1 (es) 1980-10-11 1982-05-25 "procedimiento para la preparacion de nuevas cefalosporinas".
ES512523A Granted ES512523A0 (es) 1980-10-11 1982-05-25 "procedimiento para la preparacion de nuevas cefalosporinas".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES505781A Granted ES505781A0 (es) 1980-10-11 1981-09-25 Procedimiento para la preparacion de nuevas cefalosporinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES512523A Granted ES512523A0 (es) 1980-10-11 1982-05-25 "procedimiento para la preparacion de nuevas cefalosporinas".

Country Status (19)

Country Link
US (1) US4362725A (es)
EP (1) EP0049814B1 (es)
JP (1) JPS5793985A (es)
AT (1) ATE11141T1 (es)
AU (1) AU542352B2 (es)
CA (1) CA1154433A (es)
DD (1) DD201684A5 (es)
DE (2) DE3038501A1 (es)
DK (1) DK446081A (es)
ES (3) ES505781A0 (es)
FI (1) FI813139L (es)
GB (1) GB2086888B (es)
GR (1) GR75376B (es)
HU (1) HU184892B (es)
IL (1) IL64018A (es)
NO (1) NO813423L (es)
NZ (1) NZ198599A (es)
PT (1) PT73789B (es)
ZA (1) ZA816986B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59152385A (ja) * 1983-02-17 1984-08-31 Shionogi & Co Ltd ヒドロキサム酸系セフアロスポリン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2924948A1 (de) * 1979-06-21 1981-01-22 Thomae Gmbh Dr K Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3038501A1 (de) 1982-05-19
NZ198599A (en) 1985-04-30
DK446081A (da) 1982-04-12
AU542352B2 (en) 1985-02-21
GB2086888B (en) 1984-07-18
EP0049814A3 (en) 1983-01-26
ES512524A0 (es) 1983-03-01
IL64018A0 (en) 1982-01-31
IL64018A (en) 1984-08-31
EP0049814B1 (de) 1985-01-09
ES8302720A1 (es) 1983-01-16
ES8304576A1 (es) 1983-03-01
ATE11141T1 (de) 1985-01-15
EP0049814A2 (de) 1982-04-21
NO813423L (no) 1982-04-13
GR75376B (es) 1984-07-13
PT73789B (de) 1983-10-14
HU184892B (en) 1984-10-29
FI813139L (fi) 1982-04-12
ES505781A0 (es) 1983-01-16
AU7620681A (en) 1982-04-22
ES512523A0 (es) 1983-03-01
ZA816986B (en) 1983-06-29
JPS5793985A (en) 1982-06-11
DE3168174D1 (en) 1985-02-21
PT73789A (de) 1981-11-01
DD201684A5 (de) 1983-08-03
US4362725A (en) 1982-12-07
CA1154433A (en) 1983-09-27
GB2086888A (en) 1982-05-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402