ES8406075A1 - Un procedimiento para la preparacion de una sal de adicion de un acido bencenosulfonico de la sultamicilina. - Google Patents
Un procedimiento para la preparacion de una sal de adicion de un acido bencenosulfonico de la sultamicilina.Info
- Publication number
- ES8406075A1 ES8406075A1 ES521728A ES521728A ES8406075A1 ES 8406075 A1 ES8406075 A1 ES 8406075A1 ES 521728 A ES521728 A ES 521728A ES 521728 A ES521728 A ES 521728A ES 8406075 A1 ES8406075 A1 ES 8406075A1
- Authority
- ES
- Spain
- Prior art keywords
- salt
- acid
- benzenosulphonic
- addition
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- 239000002253 acid Substances 0.000 title abstract 4
- OPYGFNJSCUDTBT-PMLPCWDUSA-N sultamicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(=O)OCOC(=O)[C@H]2C(S(=O)(=O)[C@H]3N2C(C3)=O)(C)C)(C)C)=CC=CC=C1 OPYGFNJSCUDTBT-PMLPCWDUSA-N 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- SRSXLGNVWSONIS-UHFFFAOYSA-N benzenesulfonic acid Chemical compound OS(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/371,156 US4432987A (en) | 1982-04-23 | 1982-04-23 | Crystalline benzenesulfonate salts of sultamicillin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES521728A0 ES521728A0 (es) | 1984-07-01 |
| ES8406075A1 true ES8406075A1 (es) | 1984-07-01 |
Family
ID=23462725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521728A Expired ES8406075A1 (es) | 1982-04-23 | 1983-04-21 | Un procedimiento para la preparacion de una sal de adicion de un acido bencenosulfonico de la sultamicilina. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4432987A (h) |
| EP (1) | EP0092968B1 (h) |
| JP (1) | JPS58201792A (h) |
| KR (1) | KR860001279B1 (h) |
| AU (1) | AU536854B2 (h) |
| CA (1) | CA1187484A (h) |
| CS (1) | CS235320B2 (h) |
| DD (1) | DD209632A5 (h) |
| DE (1) | DE3362502D1 (h) |
| DK (1) | DK162168C (h) |
| EG (1) | EG16412A (h) |
| ES (1) | ES8406075A1 (h) |
| FI (1) | FI76092C (h) |
| GR (1) | GR78582B (h) |
| HK (1) | HK20588A (h) |
| HU (1) | HU187068B (h) |
| IE (1) | IE54628B1 (h) |
| IL (1) | IL68453A (h) |
| NO (1) | NO156202C (h) |
| NZ (1) | NZ203988A (h) |
| PH (1) | PH18035A (h) |
| PL (1) | PL134978B1 (h) |
| PT (1) | PT76587B (h) |
| SG (1) | SG104087G (h) |
| SU (1) | SU1138030A3 (h) |
| YU (1) | YU43170B (h) |
| ZA (1) | ZA832845B (h) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5336762A (en) * | 1985-11-18 | 1994-08-09 | Access Pharmaceuticals, Inc. | Polychelating agents for image and spectral enhancement (and spectral shift) |
| JPH07110815B2 (ja) * | 1985-11-18 | 1995-11-29 | ボ−ド・オブ・リ−ジェンツ、ザ・ユニバ−シティ−・オブ・テキサス・システム | 画像及びスペクトル向上（およびスペクトルシフト）のためのポリキレ−ト剤 |
| KR910009271B1 (ko) * | 1989-06-20 | 1991-11-08 | 김영설 | 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염 |
| DE69528166T2 (de) * | 1994-05-02 | 2003-04-30 | Shionogi & Co., Ltd. | Kristalline pyrrolidylthiocarbapenem derivate, lyophilisierste präparationen dieser kristalle und verfahren zu deren herstellung |
| JP3382159B2 (ja) * | 1998-08-05 | 2003-03-04 | 株式会社東芝 | 情報記録媒体とその再生方法及び記録方法 |
| BR0313831A (pt) | 2002-08-29 | 2005-07-05 | Taisho Pharmaceutical Co Ltd | Sais benzenossulfonato de derivados de 4-flúor-2-cianopirrolidina |
| PT1606293E (pt) * | 2003-03-27 | 2009-10-14 | Basilea Pharmaceutica Ag | Cefalosporina sob forma cristalina |
| WO2005041924A2 (en) * | 2003-10-31 | 2005-05-12 | Alza Corporation | Administration of levodopa and carbidopa |
| FR2877696B1 (fr) | 2004-11-09 | 2009-09-18 | Renault Sas | Dispositif et procede d'estimation en temps reel de l'angle de debut de combustion d'un moteur a combustion interne |
| AU2008290329B2 (en) | 2007-08-22 | 2011-12-22 | Astrazeneca Ab | Cyclopropyl amide derivatives |
| WO2009055053A2 (en) | 2007-10-26 | 2009-04-30 | The Regents Of The University Of California | Diarylhydantoin compounds as androgen receptor modulators |
| MY161598A (en) * | 2009-01-30 | 2017-04-28 | Glaxosmithkline Llc | Crystalline n-{ (1s)-2-amino-1-[(3-fluorophenyl)methyl]ethyl} -5-chloro-4-(4-chloro-1-methyl-1h-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride |
| TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| WO2011006061A1 (en) * | 2009-07-10 | 2011-01-13 | Evolva Sa | Diyne compositions |
| AU2011218490B9 (en) * | 2010-02-18 | 2014-12-18 | Astrazeneca Ab | Solid forms comprising a cyclopropyl amide derivative |
| CA2788444A1 (en) * | 2010-02-18 | 2011-08-25 | Astrazeneca Ab | New crystalline form of a cyclopropyl benzamide derivative |
| WO2014087972A1 (ja) * | 2012-12-03 | 2014-06-12 | 株式会社カネカ | 還元型補酵素ｑ10誘導体およびその製造方法 |
| CN105517992B (zh) * | 2013-09-05 | 2018-06-22 | 田边三菱制药株式会社 | 新型结晶性芳烷基胺化合物及其制造方法 |
| CA2965169C (en) | 2014-10-21 | 2021-11-16 | Ariad Pharmaceuticals, Inc. | Crystalline forms of 5-chloro-n4-[2-(dimethylphosphoryl)phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrimidine-2,4-diamine |
| CN104958318A (zh) * | 2015-08-04 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗感染性疾病的药物舒巴坦钠组合物 |
| WO2017125557A1 (en) * | 2016-01-22 | 2017-07-27 | Sandoz Ag | Crystalline eravacycline bis-hydrochloride |
| MA45588A (fr) * | 2016-07-07 | 2019-05-15 | Ironwood Pharmaceuticals Inc | Formes solides d'un stimulateur de la gcs |
| WO2019089540A1 (en) * | 2017-10-30 | 2019-05-09 | Theracaine Llc | Hydrophobic arenesulfonate salts |
| US11186556B1 (en) * | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
| UA119735C2 (uk) | 2018-12-20 | 2019-07-25 | Анатолій Семенович Редер | Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу |
| USD1077123S1 (en) | 2019-02-13 | 2025-05-27 | Hs Produkt D.O.O. | Firearm sight |
| USD1071069S1 (en) | 2019-02-13 | 2025-04-15 | Hs Produkt D.O.O. | Stippled textured body for a firearm or the like |
| USD994821S1 (en) | 2019-02-13 | 2023-08-08 | Hs Produkt D.O.O. | Pistol |
| USD1057880S1 (en) | 2019-08-09 | 2025-01-14 | Hs Produkt D.O.O. | Pistol |
| WO2022174134A1 (en) * | 2021-02-15 | 2022-08-18 | Propella Therapeutics, Inc. | Abiraterone prodrugs |
| USD1049292S1 (en) * | 2021-04-06 | 2024-10-29 | Springfield, Inc. | Pistol |
| US11851424B2 (en) * | 2021-05-14 | 2023-12-26 | Global Blood Therapeutics, Inc. | Solid forms of a modulator of hemoglobin |
| USD1069964S1 (en) | 2021-11-03 | 2025-04-08 | Hs Produkt D.O.O. | Pistol slide |
| WO2023125700A1 (zh) * | 2021-12-28 | 2023-07-06 | 南京明德新药研发有限公司 | 四氢环庚吲唑化合物的盐型、晶型 |
| USD1072997S1 (en) | 2022-08-29 | 2025-04-29 | Springfield, Inc. | Firearm |
| USD1057882S1 (en) | 2022-08-29 | 2025-01-14 | Springfield, Inc. | Combined serrations for a firearm slide |
| USD1061781S1 (en) | 2022-11-30 | 2025-02-11 | Hs Produkt D.O.O. | Pistol |
| TW202517651A (zh) * | 2023-07-17 | 2025-05-01 | 美商庫拉腫瘤技術股份有限公司 | Menin抑制劑之晶型 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234579A (en) * | 1977-06-07 | 1980-11-18 | Pfizer Inc. | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors |
| KR830001903B1 (ko) * | 1979-02-13 | 1983-09-19 | 레오 파마슈티칼 프로덕츠 리미티드 | 페니실란산유도체의 제조방법 |
| IE49880B1 (en) * | 1979-02-13 | 1986-01-08 | Leo Pharm Prod Ltd | Penicillin derivatives |
| US4244951A (en) * | 1979-05-16 | 1981-01-13 | Pfizer Inc. | Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide |
| GB2084572B (en) * | 1980-10-06 | 1984-07-11 | Leo Pharm Prod Ltd | 1,1-dioxopenicillanoyloxymethyl 6-(d-aphenylacetamido)penicillanate napsylate |
| IE51516B1 (en) * | 1980-10-06 | 1987-01-07 | Leo Pharm Prod Ltd | 1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate |
| IL64009A (en) * | 1980-10-31 | 1984-09-30 | Rech Applications Therap | Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate tosylate hydrates,their production and pharmaceutical compositions containing them |
-
1982
- 1982-04-23 US US06/371,156 patent/US4432987A/en not_active Expired - Lifetime
-
1983
- 1983-02-28 DK DK101783A patent/DK162168C/da not_active IP Right Cessation
- 1983-04-19 SU SU833578255A patent/SU1138030A3/ru active
- 1983-04-19 PL PL1983241553A patent/PL134978B1/pl unknown
- 1983-04-20 CS CS832817A patent/CS235320B2/cs unknown
- 1983-04-20 DE DE8383302238T patent/DE3362502D1/de not_active Expired
- 1983-04-20 EP EP83302238A patent/EP0092968B1/en not_active Expired
- 1983-04-20 EG EG249/83A patent/EG16412A/xx active
- 1983-04-21 YU YU904/83A patent/YU43170B/xx unknown
- 1983-04-21 DD DD83250080A patent/DD209632A5/de not_active IP Right Cessation
- 1983-04-21 IL IL68453A patent/IL68453A/xx not_active IP Right Cessation
- 1983-04-21 CA CA000426451A patent/CA1187484A/en not_active Expired
- 1983-04-21 PH PH28804A patent/PH18035A/en unknown
- 1983-04-21 GR GR71155A patent/GR78582B/el unknown
- 1983-04-21 ES ES521728A patent/ES8406075A1/es not_active Expired
- 1983-04-22 HU HU831409A patent/HU187068B/hu unknown
- 1983-04-22 PT PT76587A patent/PT76587B/pt unknown
- 1983-04-22 NO NO831430A patent/NO156202C/no not_active IP Right Cessation
- 1983-04-22 JP JP58071315A patent/JPS58201792A/ja active Granted
- 1983-04-22 FI FI831392A patent/FI76092C/fi not_active IP Right Cessation
- 1983-04-22 ZA ZA832845A patent/ZA832845B/xx unknown
- 1983-04-22 IE IE926/83A patent/IE54628B1/en not_active IP Right Cessation
- 1983-04-22 AU AU13871/83A patent/AU536854B2/en not_active Expired
- 1983-04-22 NZ NZ203988A patent/NZ203988A/en unknown
- 1983-04-22 KR KR1019830001708A patent/KR860001279B1/ko not_active Expired
-
1987
- 1987-11-25 SG SG1040/87A patent/SG104087G/en unknown
-
1988
- 1988-03-17 HK HK205/88A patent/HK20588A/en not_active IP Right Cessation
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