NZ199722A
(en)
*
|
1981-02-25 |
1985-12-13 |
Genentech Inc |
Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
|
JPS58146281A
(ja)
*
|
1981-10-19 |
1983-08-31 |
Suntory Ltd |
酵母細胞の形質転換法
|
US4775622A
(en)
*
|
1982-03-08 |
1988-10-04 |
Genentech, Inc. |
Expression, processing and secretion of heterologous protein by yeast
|
CA1224735A
(en)
*
|
1982-05-19 |
1987-07-28 |
Cornelius P. Hollenberg |
Cloning system for kluyveromyces species
|
GB2125047B
(en)
*
|
1982-08-09 |
1986-02-19 |
Ciba Geigy Ag |
Yeast hybrid vectors and their use for the production of polypeptides
|
AU577259B2
(en)
*
|
1982-08-13 |
1988-09-22 |
Zymogenetics Inc. |
Glycolytic promters for regulated protein expression protease inhibitor
|
JPS5931799A
(ja)
*
|
1982-08-16 |
1984-02-20 |
Science & Tech Agency |
B型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
|
US4977092A
(en)
*
|
1985-06-26 |
1990-12-11 |
Amgen |
Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
|
DE3382547D1
(de)
*
|
1983-01-12 |
1992-05-27 |
Chiron Corp |
Sekretorische expression in eukaryoten.
|
US5089398A
(en)
*
|
1983-02-22 |
1992-02-18 |
Chiron Corporation |
Enhanced yeast transcription employing hybrid GAPDH promoter region constructs
|
US4876197A
(en)
*
|
1983-02-22 |
1989-10-24 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
JPS60501140A
(ja)
*
|
1983-04-22 |
1985-07-25 |
アムジエン |
酵母による外因性ポリペプチドの分泌
|
JPS60501290A
(ja)
*
|
1983-05-19 |
1985-08-15 |
ユニリ−バ− ナ−ムロ−ゼ ベンノ−トシヤ−プ |
酵母細胞に新しく導入した遺伝子の発現改良
|
EP0143821A1
(fr)
*
|
1983-05-19 |
1985-06-12 |
Transgene S.A. |
Production de la catechol 2,3-oxygenase par des levures, plasmide pour sa mise en oeuvre et application
|
FR2561662B2
(fr)
*
|
1984-03-22 |
1986-08-22 |
Transgene Sa |
Bloc d'expression de la catechol 2,3-oxygenase dans les levures et souche marquee par ce bloc d'expression
|
GB8314961D0
(en)
*
|
1983-05-31 |
1983-07-06 |
Kingsman A J |
Dna sequence
|
US4870008A
(en)
*
|
1983-08-12 |
1989-09-26 |
Chiron Corporation |
Secretory expression in eukaryotes
|
GB8325043D0
(en)
*
|
1983-09-19 |
1983-10-19 |
Kingsman A J |
Vector
|
FR2552776B1
(fr)
*
|
1983-10-03 |
1986-05-09 |
Transgene Sa |
Vecteurs d'expression d'une proteine antigenique de la rage dans les cellules eucaryotes et leur application a la preparation d'un vaccin
|
WO1985001516A1
(fr)
*
|
1983-10-03 |
1985-04-11 |
Transgene S.A. |
Vecteurs d'expression d'une proteine antigenique de la rage dans les cellules eucaryotes et leur application a la preparation d'un vaccin
|
FR2562090B2
(fr)
*
|
1984-03-27 |
1988-04-08 |
Transgene Sa |
Proteine antigenique de la rage glycosylee
|
GB8334261D0
(en)
*
|
1983-12-22 |
1984-02-01 |
Bass Plc |
Fermentation processes
|
AU587176B2
(en)
*
|
1984-02-14 |
1989-08-10 |
Mycogen Plant Science, Inc. |
Transfer vector
|
FR2559782B1
(fr)
*
|
1984-02-16 |
1986-07-18 |
Transgene Sa |
Vecteur d'expression dans les levures de l'interleukine-2, levures transformees et procede de preparation de l'interleukine-2
|
FI841500A0
(fi)
*
|
1984-04-13 |
1984-04-13 |
Valtion Teknillinen |
Foerfarande foer uppbygnande av cellulolytiska jaeststammar.
|
FR2564106B1
(fr)
*
|
1984-05-09 |
1988-04-22 |
Transgene Sa |
Vecteurs d'expression du facteur ix, cellules transformees par ces vecteurs et procede de preparation du facteur ix.
|
US4880734A
(en)
*
|
1984-05-11 |
1989-11-14 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
DK58285D0
(da)
*
|
1984-05-30 |
1985-02-08 |
Novo Industri As |
Peptider samt fremstilling og anvendelse deraf
|
SU1364343A1
(ru)
*
|
1984-07-13 |
1988-01-07 |
Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов |
Способ получени человеческого лейкоцитарного интерферона альфа-2
|
US4762786A
(en)
*
|
1984-09-27 |
1988-08-09 |
Eli Lilly And Company |
Vectors and conditions which allow genetic transformation of cephalosporium
|
US4885242A
(en)
*
|
1984-10-30 |
1989-12-05 |
Phillips Petroleum Company |
Genes from pichia histidine pathway and uses thereof
|
US4855231A
(en)
*
|
1984-10-30 |
1989-08-08 |
Phillips Petroleum Company |
Regulatory region for heterologous gene expression in yeast
|
US7273695B1
(en)
|
1984-10-31 |
2007-09-25 |
Novartis Vaccines And Diagnostics, Inc. |
HIV immunoassays using synthetic envelope polypeptides
|
US7393949B1
(en)
|
1987-12-24 |
2008-07-01 |
Novartis Vaccines And Diagnostics, Inc. |
Human immunodeficiency virus (HIV) nucleotide sequences
|
US7285271B1
(en)
|
1984-10-31 |
2007-10-23 |
Novartis Vaccines And Diagnostics, Inc. |
Antigenic composition comprising an HIV gag or env polypeptide
|
CA1341482C
(en)
|
1984-10-31 |
2005-05-10 |
Paul A. Luciw |
Process for preparing fragments of aids-associated retroviruses
|
JPS61268184A
(ja)
*
|
1984-11-05 |
1986-11-27 |
Green Cross Corp:The |
組換えプラスミド及び当該プラスミドによる形質転換株
|
US4990446A
(en)
*
|
1984-12-06 |
1991-02-05 |
Labofina, S.A. |
Promoters for the expression of foreign genes in yeast, plasmids comprising them, and use thereof for the production of polypeptides
|
JPS61141890A
(ja)
*
|
1984-12-15 |
1986-06-28 |
Suntory Ltd |
アルコ−ルの製造法
|
GB8513645D0
(en)
*
|
1985-05-30 |
1985-07-03 |
Kingsman A J |
Expression vector
|
US4882282A
(en)
*
|
1985-08-16 |
1989-11-21 |
Immunex Corporation |
DNA sequences encoding bovine interleukin-2
|
WO1987002037A1
(en)
*
|
1985-09-26 |
1987-04-09 |
Genetics Institute, Inc. |
Pulmonary surfactant proteins
|
AU621277B2
(en)
*
|
1985-11-13 |
1992-03-12 |
Xoma Corporation |
Shortened phosphoglycerate kinase promoter
|
US5104795A
(en)
*
|
1985-11-13 |
1992-04-14 |
Zoma Corporation |
Shortened phosphoglycerate kinase promoter
|
GB8620926D0
(en)
*
|
1986-08-29 |
1986-10-08 |
Delta Biotechnology Ltd |
Yeast promoter
|
DE3635867A1
(de)
*
|
1986-10-22 |
1988-05-11 |
Boehringer Ingelheim Int |
Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
|
US5378603A
(en)
*
|
1987-03-30 |
1995-01-03 |
Board Of Regents, The University Of Texas System |
Method and composition for identifying substances which activate transcription of the LDL receptor gene
|
JPS6463395A
(en)
|
1987-05-04 |
1989-03-09 |
Oncogen |
Oncostatin m and novel composition having antitumor activity
|
US4966841A
(en)
*
|
1987-05-22 |
1990-10-30 |
The Board Of Regents Of The University Of Washington |
Enhanced vector production and expression of recombinant DNA products
|
DE3855634T2
(de)
|
1987-06-23 |
1997-02-27 |
Univ Leland Stanford Junior |
Innerhalb des alpha-Locus gelegenes T-Zell-Rezeptor-Gen und DNA-Konstruktionen
|
US5063154A
(en)
*
|
1987-06-24 |
1991-11-05 |
Whitehead Institute For Biomedical Research |
Pheromone - inducible yeast promoter
|
WO1988010308A1
(en)
*
|
1987-06-24 |
1988-12-29 |
Whitehead Institute For Biomedical Research |
Pheromone-inducible yeast promoter
|
US5591603A
(en)
*
|
1987-08-28 |
1997-01-07 |
Novo Nordisk A/S |
Process for preparing aprotinin and aprotinin analogs in yeast cells
|
US5049493A
(en)
*
|
1987-10-23 |
1991-09-17 |
California Institute Of Technology |
Enhancement of cell growth by expression of a cloned hemoglobin gene
|
FR2628750B1
(fr)
|
1988-03-21 |
1991-11-08 |
Pasteur Institut |
Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire
|
US5258502A
(en)
*
|
1989-01-30 |
1993-11-02 |
Massachusetts Institute Of Technology |
Immobilization and purification of fusion proteins using chitin-binding ability
|
US6172039B1
(en)
|
1990-04-16 |
2001-01-09 |
Apex Bioscience, Inc. |
Expression of recombinant hemoglobin and hemoglobin variants in yeast
|
US5206153A
(en)
*
|
1990-06-27 |
1993-04-27 |
Snow Brand Milk Products Co., Ltd. |
Method of producing human α-fetoprotein and product produced thereby
|
EP1029915A3
(en)
*
|
1990-09-13 |
2004-11-17 |
Duke University |
Expression of G protein coupled receptors in yeast
|
US6027722A
(en)
*
|
1990-10-25 |
2000-02-22 |
Nature Technology Corporation |
Vectors for gene transfer
|
ES2121794T3
(es)
*
|
1990-10-25 |
1998-12-16 |
Clague Pitman Hodgson |
Procedimiento de transferencia de genes por medio de retrotransposones.
|
EP0501914A1
(en)
*
|
1991-02-25 |
1992-09-02 |
Ciba-Geigy Ag |
Improved yeast vectors
|
US20100267023A1
(en)
*
|
1992-09-24 |
2010-10-21 |
Keygene N.V. |
Selective restriction fragment amplification: fingerprinting
|
US5422254A
(en)
*
|
1992-02-14 |
1995-06-06 |
Oy Alko Ab |
Method to increase the trehalose content of organisms by transforming them with the structural genes for the short and long chains of yeast trehalose synthase
|
AU699706C
(en)
|
1993-03-12 |
2000-01-13 |
Creighton University |
Improved vectors for gene therapy
|
US20030190753A1
(en)
*
|
1995-11-09 |
2003-10-09 |
Nature Technology Corporation |
Vectors for gene transfer
|
PL192537B1
(pl)
|
1996-10-16 |
2006-11-30 |
Zymogenetics Inc |
Izolowana cząsteczka polinukleotydu kodująca polipeptyd homologiczny z czynnikiem wzrostu fibroblastów (FGF), wektor ekspresji, hodowane komórki, sposób wytwarzania polipeptydu, izolowany polipeptyd, polipeptyd homologiczny, kompozycja farmaceutyczna, przeciwciało, zastosowanie polipeptydu, sposób stymulacji i zastosowanie cząsteczki zawierającej polipeptyd FGF sprzężonej z drugą cząsteczką
|
US6017694A
(en)
*
|
1997-12-19 |
2000-01-25 |
American Cyanamid Company |
Methods of screening for modulators of respiratory syncytial virus matrix protein interaction
|
ES2329741T3
(es)
|
1998-09-23 |
2009-11-30 |
Zymogenetics, Inc. |
Receptor de citoquinas zalpha11.
|
ES2432053T3
(es)
|
1998-12-07 |
2013-11-29 |
Zymogenetics, Inc. |
Homólogo del factor del crecimiento ZVEGF3
|
ATE249517T1
(de)
|
1999-01-07 |
2003-09-15 |
Zymogenetics Inc |
Lösliche rezeptoren br43x2 und verfahren zu deren therapeutischen verwendung
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
KR100743640B1
(ko)
|
1999-03-09 |
2007-07-27 |
지모제넥틱스, 인코포레이티드 |
신규한 사이토킨 zalpha 11 리간드
|
JP4737903B2
(ja)
|
1999-07-07 |
2011-08-03 |
ザイモジェネティクス, インコーポレイテッド |
ヒトサイトカイン受容体
|
EP2194130A1
(en)
|
1999-12-23 |
2010-06-09 |
ZymoGenetics, L.L.C. |
Cytokine ZCYTO18
|
EP1278852B1
(en)
|
2000-05-11 |
2010-07-07 |
ZymoGenetics, Inc. |
Zsig33-like peptides
|
WO2002000721A2
(en)
|
2000-06-26 |
2002-01-03 |
Zymogenetics, Inc. |
Cytokine receptor zcytor17
|
ATE404670T1
(de)
|
2000-06-30 |
2008-08-15 |
Zymogenetics Inc |
Allelische variante des interferon-ähnlichen proteins zcyto21
|
EP1736545A3
(en)
|
2000-08-08 |
2007-03-28 |
ZymoGenetics, Inc. |
Soluble zcytor 11 cytokine receptors
|
US20030012783A1
(en)
|
2001-02-20 |
2003-01-16 |
Wayne Kindsvogel |
Antibodies that bind both BCMA and TACI
|
FR2821625B1
(fr)
*
|
2001-03-01 |
2003-05-16 |
Genodyssee |
Nouveaux polynucleotides comportant un polymorphisme de type snp fonctionnel dans la sequence nucleotidique du gene ifn-alpha-2 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
|
FR2823220B1
(fr)
*
|
2001-04-04 |
2003-12-12 |
Genodyssee |
Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
|
PL403488A1
(pl)
|
2001-05-24 |
2013-07-08 |
Zymogenetics, Inc. |
Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
|
US6645739B2
(en)
|
2001-07-26 |
2003-11-11 |
Phoenix Pharmacologies, Inc. |
Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
|
AU2002330022B2
(en)
|
2001-09-13 |
2007-07-12 |
California Institute Of Technology |
Method for producing transgenic birds and fish
|
AU2002326907B2
(en)
|
2001-09-13 |
2008-04-03 |
California Institute Of Technology |
Method for expression of small RNA molecules within a cell
|
ES2334338T3
(es)
|
2001-11-05 |
2010-03-09 |
Zymogenetics, Inc. |
Antagonistas de il-21.
|
PL211833B1
(pl)
|
2002-01-18 |
2012-06-29 |
Zymogenetics Inc |
Wyizolowany polipeptyd, białko fuzyjne, wyizolowana cząsteczka polinukleotydu, wektor ekspresji, hodowana komórka, sposób wytwarzania polipeptydu, sposób wytwarzania przeciwciała, przeciwciało, przeciwciało lub fragment przeciwciała, zastosowanie przeciwciała, sposób wykrywania obecności polipeptydu, sposób inhibicji proliferacji lub różnicowania komórek krwiotwórczych, zastosowanie polipeptydu, sposób rozprzestrzeniania komórek krwiotwórczych, sposób wykrywania obecności RNA, sposób zabijania komórek nowotworowych in vitro lub in vivo, zastosowanie polipeptydu, zastosowanie antagonisty polipeptydu i sposób wykrywania zapalenia u pacjenta
|
EP2840089A1
(en)
|
2002-01-18 |
2015-02-25 |
ZymoGenetics, Inc. |
Cytokine receptor zcytor17 multimers
|
DE60335536D1
(de)
|
2002-04-19 |
2011-02-10 |
Bristol Myers Squibb Co |
Verfahren zum nachweis oder zur modulierung der wechselwirkung eines cytokinrezeptors mit seinem ligand
|
PL2251353T3
(pl)
|
2003-08-07 |
2013-08-30 |
Zymogenetics Inc |
Homogenne preparaty IL-29
|
EP1732946B1
(en)
|
2004-03-08 |
2011-07-27 |
ZymoGenetics, Inc. |
Dimeric fusion proteins and materials and methods for producing them
|
CN101829318B
(zh)
|
2004-07-29 |
2012-07-04 |
津莫吉尼蒂克斯有限责任公司 |
Il-28和il-29治疗癌症和自身免疫性疾病的用途
|
EP2166103B1
(en)
|
2004-08-02 |
2013-05-22 |
BASF Plant Science GmbH |
Method for isolation of transcription termination sequences
|
WO2006086396A2
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
ES2609429T3
(es)
|
2005-05-12 |
2017-04-20 |
Zymogenetics, Inc. |
Composiciones y métodos para modular respuestas inmunitarias
|
JP5118037B2
(ja)
|
2005-08-09 |
2013-01-16 |
ザイモジェネティクス, インコーポレイテッド |
Taci融合分子を用いた異常細胞増殖の処置及び予防のための方法
|
AU2006278229B2
(en)
*
|
2005-08-09 |
2011-10-27 |
Ares Trading S.A. |
Methods for treating B-cell malignancies using TACI-Ig fusion molecule
|
EP2035028A2
(en)
*
|
2006-05-15 |
2009-03-18 |
Ares Trading S.A. |
Methods for treating autoimmune diseases using a taci-ig fusion molecule
|
EP2164863A4
(en)
|
2007-06-15 |
2010-07-28 |
Univ Arkansas |
METHOD FOR THE ADMINISTRATION OF MOLECULES IN CELLS USING A RICIN SUB-UNIT AND RELATED COMPOSITIONS THEREOF
|
CA2706550C
(en)
|
2007-11-21 |
2021-12-14 |
Roskilde Universitet |
Polypeptides comprising an ice-binding activity
|
WO2009080054A1
(en)
*
|
2007-12-21 |
2009-07-02 |
Ifxa A/S |
Protease inhibitor
|
JP5727792B2
(ja)
*
|
2008-01-25 |
2015-06-03 |
オーフス ユニバーシテ |
Igfbp−4に対するpapp−a活性の選択的エキソサイト阻害
|
SI2274008T1
(sl)
|
2008-03-27 |
2014-08-29 |
Zymogenetics, Inc. |
Sestavki in metode za zaviranje PDGFRBETA in VEGF-A
|
US8658766B2
(en)
|
2008-06-27 |
2014-02-25 |
Zymogenetics, Inc. |
Soluble hybrid Fcγ receptors and related methods
|
WO2011156356A1
(en)
|
2010-06-09 |
2011-12-15 |
Zymogenetics, Inc. |
Dimeric vstm3 fusion proteins and related compositions and methods
|
EP2809795B1
(en)
|
2012-02-01 |
2019-09-18 |
SGI-DNA, Inc. |
Materials and methods for the synthesis of error-minimized nucleic acid molecules
|
WO2014202089A2
(en)
|
2013-06-18 |
2014-12-24 |
Roskilde Universitet |
Variants of anti-freeze polypeptides
|
CA2997263C
(en)
|
2015-09-08 |
2022-10-04 |
Theripion, Inc. |
Apoa-1 fusion polypeptides and related compositions and methods
|
WO2018136163A2
(en)
|
2016-12-09 |
2018-07-26 |
Theripion, Inc. |
Tandem apoa-1 fusion polypeptides
|
EP3655439A1
(en)
|
2017-07-20 |
2020-05-27 |
Aptevo Research and Development LLC |
Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
|
RU2756100C1
(ru)
|
2017-12-20 |
2021-09-28 |
Харбор Байомед (Шанхай) Ко., Лтд |
Антитела, связывающие ctla-4, и их применение
|
US10150801B1
(en)
|
2017-12-27 |
2018-12-11 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
WO2019132765A1
(en)
|
2017-12-27 |
2019-07-04 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
US10675332B1
(en)
|
2019-08-26 |
2020-06-09 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
EP4021512A1
(en)
|
2019-08-26 |
2022-07-06 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
CA3182917A1
(en)
|
2020-06-22 |
2021-12-30 |
Ya-Huei Chen |
Recombinant polypeptides and combinations for use in the treatment of cancer
|
CA3207134A1
(en)
|
2021-02-19 |
2022-08-25 |
Jeffrey A. Ledbetter |
Dnase fusion polypeptides and related compositions and methods
|