ES470470A1 - Un procedimiento para la preparacion de ftalazinas - Google Patents

Un procedimiento para la preparacion de ftalazinas

Info

Publication number
ES470470A1
ES470470A1 ES470470A ES470470A ES470470A1 ES 470470 A1 ES470470 A1 ES 470470A1 ES 470470 A ES470470 A ES 470470A ES 470470 A ES470470 A ES 470470A ES 470470 A1 ES470470 A1 ES 470470A1
Authority
ES
Spain
Prior art keywords
piperidinophthalazines
formula
cardiac stimulants
attached
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470470A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of ES470470A1 publication Critical patent/ES470470A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES470470A 1977-06-03 1978-06-02 Un procedimiento para la preparacion de ftalazinas Expired ES470470A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (1)

Publication Number Publication Date
ES470470A1 true ES470470A1 (es) 1979-09-01

Family

ID=10198020

Family Applications (4)

Application Number Title Priority Date Filing Date
ES470470A Expired ES470470A1 (es) 1977-06-03 1978-06-02 Un procedimiento para la preparacion de ftalazinas
ES478201A Expired ES478201A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de ftalazinas.
ES478199A Expired ES478199A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de etalazinas.
ES478200A Expired ES478200A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de ftalazinas.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES478201A Expired ES478201A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de ftalazinas.
ES478199A Expired ES478199A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de etalazinas.
ES478200A Expired ES478200A1 (es) 1977-06-03 1979-03-01 Un procedimiento para la preparacion de ftalazinas.

Country Status (29)

Country Link
US (1) US4289772A (en, 2012)
JP (1) JPS5416488A (en, 2012)
AR (2) AR222013A1 (en, 2012)
AT (2) AT362792B (en, 2012)
AU (1) AU505373B1 (en, 2012)
BE (1) BE867727A (en, 2012)
CA (1) CA1111850A (en, 2012)
DD (1) DD137355A5 (en, 2012)
DE (1) DE2824064A1 (en, 2012)
DK (1) DK248078A (en, 2012)
EG (1) EG13527A (en, 2012)
ES (4) ES470470A1 (en, 2012)
FI (1) FI781753A7 (en, 2012)
FR (1) FR2392986A1 (en, 2012)
GB (1) GB2000136B (en, 2012)
GR (1) GR74402B (en, 2012)
HU (1) HU179745B (en, 2012)
IL (1) IL54842A (en, 2012)
IN (3) IN148482B (en, 2012)
IT (1) IT1094944B (en, 2012)
LU (1) LU79761A1 (en, 2012)
NL (1) NL7806016A (en, 2012)
NO (1) NO781935L (en, 2012)
NZ (1) NZ187453A (en, 2012)
PL (3) PL116420B1 (en, 2012)
PT (1) PT68126A (en, 2012)
SE (1) SE7806519L (en, 2012)
SU (2) SU856383A3 (en, 2012)
ZA (1) ZA783183B (en, 2012)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
GR73576B (en, 2012) * 1980-03-01 1984-03-20 Wyeth John & Brother Ltd
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
AU5772196A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
NZ333354A (en) * 1996-08-20 2000-05-26 Eisai Co Ltd Fused pyridazine compounds for erectile dysfunction
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
MXPA05001859A (es) * 2002-08-16 2005-06-03 Johnson & Johnson Compuestos de piperidinilo que se unen selectivamente a las integrinas.
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100222353A1 (en) * 2006-01-27 2010-09-02 Pfizer Products Inc. Aminophthalazine derivative compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
US8937181B2 (en) 2006-04-13 2015-01-20 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
AU2007249435A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
ATE517100T1 (de) 2007-08-07 2011-08-15 Hoffmann La Roche Pyrrolidinarylether als nk3-rezeptorantagonisten
EP2190815B1 (en) 2007-08-22 2011-08-10 F. Hoffmann-La Roche AG Pyrrolidine aryl-ether as nk3 receptor antagonists
KR101174980B1 (ko) * 2007-09-14 2012-08-17 에프. 호프만-라 로슈 아게 Ｎｋ３ 수용체 길항제로서의 피페리딘 유도체
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP2023546536A (ja) 2020-10-13 2023-11-02 エンデバー バイオメディシンズ， インコーポレイテッド 線維症を処置する方法
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
AR223999A1 (es) 1981-10-15
ZA783183B (en) 1979-06-27
NO781935L (no) 1978-12-05
DK248078A (da) 1978-12-04
FR2392986A1 (fr) 1978-12-29
LU79761A1 (fr) 1980-01-22
EG13527A (en) 1981-12-31
AT363096B (de) 1981-07-10
IN149550B (en, 2012) 1982-01-16
NZ187453A (en) 1980-12-19
JPS5538351B2 (en, 2012) 1980-10-03
FR2392986B1 (en, 2012) 1982-07-16
ES478199A1 (es) 1980-01-16
PT68126A (en) 1978-07-01
PL116437B1 (en) 1981-06-30
ES478200A1 (es) 1980-01-01
GB2000136A (en) 1979-01-04
DE2824064A1 (de) 1978-12-14
CA1111850A (en) 1981-11-03
IL54842A (en) 1982-01-31
JPS5416488A (en) 1979-02-07
PL116420B1 (en) 1981-06-30
AR222013A1 (es) 1981-04-15
IL54842A0 (en) 1978-08-31
HU179745B (en) 1982-12-28
ATA400878A (de) 1980-11-15
IT7824106A0 (it) 1978-06-01
SU862826A3 (ru) 1981-09-07
IN148482B (en, 2012) 1981-03-07
AU505373B1 (en) 1979-11-15
SE7806519L (sv) 1978-12-04
PL207337A1 (pl) 1979-06-04
IN149973B (en, 2012) 1982-06-19
SU856383A3 (ru) 1981-08-15
GB2000136B (en) 1982-01-06
PL113208B1 (en) 1980-11-29
ATA305080A (de) 1980-12-15
NL7806016A (nl) 1978-12-05
DD137355A5 (de) 1979-08-29
AT362792B (de) 1981-06-10
GR74402B (en, 2012) 1984-06-28
IT1094944B (it) 1985-08-10
FI781753A7 (fi) 1978-12-04
US4289772A (en) 1981-09-15
ES478201A1 (es) 1980-02-01
BE867727A (fr) 1978-12-01

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