ES485361A1 - Procedimiento para preparar derivados de pirrolidina - Google Patents
Procedimiento para preparar derivados de pirrolidinaInfo
- Publication number
- ES485361A1 ES485361A1 ES485361A ES485361A ES485361A1 ES 485361 A1 ES485361 A1 ES 485361A1 ES 485361 A ES485361 A ES 485361A ES 485361 A ES485361 A ES 485361A ES 485361 A1 ES485361 A1 ES 485361A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- general formula
- preparation
- chem
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005228 3‐azabicyclo[3.1.0]hexanes Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 2
- 239000013638 trimer Substances 0.000 abstract 2
- JFUYLMCSIHJLOX-UHFFFAOYSA-N 3-azabicyclo[3.1.0]hexane-2-carbonitrile Chemical compound N#CC1NCC2CC12 JFUYLMCSIHJLOX-UHFFFAOYSA-N 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para preparar derivados de pirrolidina de fórmula de fórmula general: **(Fórmula)** donde R1 representa un átomo de hidrógeno o un grupo alcohilo que puede estar sin sustituir o sustituido con uno o más grupos alcoxi, cada uno de R2, R3, R4, R5, R6 y R7, de los cuales dos o más cualesquiera pueden ser iguales o diferentes, representa un átomo de hidrógeno o un grupo alcohilo, arilo, aralcohilo o alcarilo que puede estar sin sustituir o sustituido con uno o más grupos alcoxi, X representa un átomo de hidrógeno, un grupo acilo orgánico o un grupo trialcohilsililo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7842282 | 1978-10-27 | ||
GB7916689 | 1979-05-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES485361A1 true ES485361A1 (es) | 1980-07-01 |
Family
ID=26269372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES485361A Expired ES485361A1 (es) | 1978-10-27 | 1979-10-25 | Procedimiento para preparar derivados de pirrolidina |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0010799B1 (es) |
AU (1) | AU535172B2 (es) |
BR (1) | BR7906924A (es) |
DE (1) | DE2962910D1 (es) |
ES (1) | ES485361A1 (es) |
IL (1) | IL58553A0 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5256791A (en) * | 1992-03-02 | 1993-10-26 | Pfizer Inc. | Preparation of intermediates in the synthesis of quinoline antibiotics |
JPH0912547A (ja) * | 1995-06-23 | 1997-01-14 | Chisso Corp | ニューキノロン系化合物中間体の製造方法 |
CA2634397A1 (en) | 2005-12-22 | 2007-07-05 | Schering Corporation | Process for the preparation of 6,6-dimethyl-3-azabicyclo[3.1.0|-hexane compounds and enantiomeric salts thereof |
US8158807B2 (en) | 2006-12-20 | 2012-04-17 | Schering Corporation | Process for the preparation of 6,6-dimethyl-3-azabicyclo-[3.1.0]-hexane compounds utilizing bisulfite intermediate |
JP2011504929A (ja) * | 2007-11-28 | 2011-02-17 | シェーリング コーポレイション | 6,6−ジメチル−3−アザビシクロ[3.1.0]ヘキサンを提供するのに有用な中間体調製のための脱塩化水素化プロセス |
MX2010014500A (es) * | 2008-06-24 | 2011-05-30 | Codexis Inc | Procedimientos biocataliticos para la preparacion de compuestos de prolina biciclica fusionada sustancialmente estereomericamente puros. |
CN114605308B (zh) * | 2022-03-18 | 2023-12-19 | 阜新孚隆宝医药科技有限公司 | 一种帕罗韦德的氮杂双环医药中间体的制备方法及中间体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2400454A1 (de) * | 1974-01-05 | 1975-07-10 | Bayer Ag | Mittel zur regulierung des pflanzenwachstums |
DE2419970C3 (de) * | 1974-04-25 | 1980-06-12 | Hoechst Ag, 6000 Frankfurt | 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung |
GB1567153A (en) * | 1975-09-16 | 1980-05-14 | Shell Int Research | Method of sterilizing male anthers of angiosperms |
US4118393A (en) * | 1977-06-23 | 1978-10-03 | American Cyanamid Company | Phenyl azabicyclohexanones |
-
1979
- 1979-10-15 DE DE7979200586T patent/DE2962910D1/de not_active Expired
- 1979-10-15 EP EP79200586A patent/EP0010799B1/en not_active Expired
- 1979-10-25 ES ES485361A patent/ES485361A1/es not_active Expired
- 1979-10-25 AU AU52195/79A patent/AU535172B2/en not_active Ceased
- 1979-10-25 BR BR7906924A patent/BR7906924A/pt unknown
- 1979-10-25 IL IL58553A patent/IL58553A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BR7906924A (pt) | 1980-07-15 |
AU5219579A (en) | 1980-05-01 |
AU535172B2 (en) | 1984-03-08 |
EP0010799B1 (en) | 1982-05-19 |
IL58553A0 (en) | 1980-01-31 |
DE2962910D1 (en) | 1982-07-08 |
EP0010799A1 (en) | 1980-05-14 |
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