NL7806016A - Nieuwe fthalazinederivaten. - Google Patents

Nieuwe fthalazinederivaten.

Info

Publication number
NL7806016A
NL7806016A NL7806016A NL7806016A NL7806016A NL 7806016 A NL7806016 A NL 7806016A NL 7806016 A NL7806016 A NL 7806016A NL 7806016 A NL7806016 A NL 7806016A NL 7806016 A NL7806016 A NL 7806016A
Authority
NL
Netherlands
Prior art keywords
fthalazine
derivatives
new
new fthalazine
fthalazine derivatives
Prior art date
Application number
NL7806016A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7806016A publication Critical patent/NL7806016A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
NL7806016A 1977-06-03 1978-06-02 Nieuwe fthalazinederivaten. NL7806016A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (1)

Publication Number Publication Date
NL7806016A true NL7806016A (nl) 1978-12-05

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7806016A NL7806016A (nl) 1977-06-03 1978-06-02 Nieuwe fthalazinederivaten.

Country Status (29)

Country Link
US (1) US4289772A (nl)
JP (1) JPS5416488A (nl)
AR (2) AR222013A1 (nl)
AT (2) AT362792B (nl)
AU (1) AU505373B1 (nl)
BE (1) BE867727A (nl)
CA (1) CA1111850A (nl)
DD (1) DD137355A5 (nl)
DE (1) DE2824064A1 (nl)
DK (1) DK248078A (nl)
EG (1) EG13527A (nl)
ES (4) ES470470A1 (nl)
FI (1) FI781753A (nl)
FR (1) FR2392986A1 (nl)
GB (1) GB2000136B (nl)
GR (1) GR74402B (nl)
HU (1) HU179745B (nl)
IL (1) IL54842A (nl)
IN (3) IN148482B (nl)
IT (1) IT1094944B (nl)
LU (1) LU79761A1 (nl)
NL (1) NL7806016A (nl)
NO (1) NO781935L (nl)
NZ (1) NZ187453A (nl)
PL (3) PL116420B1 (nl)
PT (1) PT68126A (nl)
SE (1) SE7806519L (nl)
SU (2) SU856383A3 (nl)
ZA (1) ZA783183B (nl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PL129174B1 (en) * 1980-03-01 1984-04-30 Wyeth John & Brother Ltd Process for preparing novel derivatives of piperidine
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
WO1996036611A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
HUP9903168A3 (en) * 1996-08-20 2002-01-28 Eisai Co Ltd Remedy for erection failure comprising fused pyridazine compound
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
UA83467C2 (uk) * 2002-08-16 2008-07-25 Янссен Фармацевтика Н.В. Сполуки піперидинілу, які вибірково зв'язують інтегрини
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
WO2007025177A2 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100222353A1 (en) * 2006-01-27 2010-09-02 Pfizer Products Inc. Aminophthalazine derivative compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
US8791264B2 (en) 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
MX2010001080A (es) 2007-08-07 2010-03-01 Hoffmann La Roche Pirrolidin-aril-eteres como antagonistas de receptor de nk3.
KR101194467B1 (ko) 2007-08-22 2012-10-24 에프. 호프만-라 로슈 아게 Ｎｋ3 수용체 길항제로서의 피롤리딘 아릴-에터
MX2010002585A (es) * 2007-09-14 2010-03-26 Hoffmann La Roche Derivados de piperidina como antagonistas del receptor nk3.
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
AR223999A1 (es) 1981-10-15
IL54842A (en) 1982-01-31
ES470470A1 (es) 1979-09-01
NZ187453A (en) 1980-12-19
NO781935L (no) 1978-12-05
SU862826A3 (ru) 1981-09-07
CA1111850A (en) 1981-11-03
PL116437B1 (en) 1981-06-30
IN149973B (nl) 1982-06-19
AT363096B (de) 1981-07-10
PL116420B1 (en) 1981-06-30
ATA305080A (de) 1980-12-15
HU179745B (en) 1982-12-28
GB2000136A (en) 1979-01-04
ZA783183B (en) 1979-06-27
DD137355A5 (de) 1979-08-29
FI781753A (fi) 1978-12-04
IN148482B (nl) 1981-03-07
ATA400878A (de) 1980-11-15
GR74402B (nl) 1984-06-28
FR2392986B1 (nl) 1982-07-16
GB2000136B (en) 1982-01-06
ES478200A1 (es) 1980-01-01
US4289772A (en) 1981-09-15
IT7824106A0 (it) 1978-06-01
EG13527A (en) 1981-12-31
FR2392986A1 (fr) 1978-12-29
PL113208B1 (en) 1980-11-29
JPS5538351B2 (nl) 1980-10-03
PT68126A (en) 1978-07-01
JPS5416488A (en) 1979-02-07
AT362792B (de) 1981-06-10
BE867727A (fr) 1978-12-01
AR222013A1 (es) 1981-04-15
IL54842A0 (en) 1978-08-31
AU505373B1 (en) 1979-11-15
SE7806519L (sv) 1978-12-04
IT1094944B (it) 1985-08-10
PL207337A1 (pl) 1979-06-04
ES478201A1 (es) 1980-02-01
ES478199A1 (es) 1980-01-16
IN149550B (nl) 1982-01-16
DE2824064A1 (de) 1978-12-14
SU856383A3 (ru) 1981-08-15
DK248078A (da) 1978-12-04
LU79761A1 (fr) 1980-01-22

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