EG13527A - 1-piperidino phthalazines as cardiac stimulants - Google Patents

1-piperidino phthalazines as cardiac stimulants

Info

Publication number
EG13527A
EG13527A EG354/78A EG35478A EG13527A EG 13527 A EG13527 A EG 13527A EG 354/78 A EG354/78 A EG 354/78A EG 35478 A EG35478 A EG 35478A EG 13527 A EG13527 A EG 13527A
Authority
EG
Egypt
Prior art keywords
phthalazines
piperidino
cardiac stimulants
stimulants
cardiac
Prior art date
Application number
EG354/78A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG13527A publication Critical patent/EG13527A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
EG354/78A 1977-06-03 1978-06-03 1-piperidino phthalazines as cardiac stimulants EG13527A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (1)

Publication Number Publication Date
EG13527A true EG13527A (en) 1981-12-31

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
EG354/78A EG13527A (en) 1977-06-03 1978-06-03 1-piperidino phthalazines as cardiac stimulants

Country Status (29)

Country Link
US (1) US4289772A (nl)
JP (1) JPS5416488A (nl)
AR (2) AR222013A1 (nl)
AT (2) AT362792B (nl)
AU (1) AU505373B1 (nl)
BE (1) BE867727A (nl)
CA (1) CA1111850A (nl)
DD (1) DD137355A5 (nl)
DE (1) DE2824064A1 (nl)
DK (1) DK248078A (nl)
EG (1) EG13527A (nl)
ES (4) ES470470A1 (nl)
FI (1) FI781753A (nl)
FR (1) FR2392986A1 (nl)
GB (1) GB2000136B (nl)
GR (1) GR74402B (nl)
HU (1) HU179745B (nl)
IL (1) IL54842A (nl)
IN (3) IN148482B (nl)
IT (1) IT1094944B (nl)
LU (1) LU79761A1 (nl)
NL (1) NL7806016A (nl)
NO (1) NO781935L (nl)
NZ (1) NZ187453A (nl)
PL (3) PL113208B1 (nl)
PT (1) PT68126A (nl)
SE (1) SE7806519L (nl)
SU (2) SU856383A3 (nl)
ZA (1) ZA783183B (nl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PL129174B1 (en) * 1980-03-01 1984-04-30 Wyeth John & Brother Ltd Process for preparing novel derivatives of piperidine
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
US5728712A (en) * 1995-05-19 1998-03-17 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
CA2258079A1 (en) * 1996-08-20 1998-02-26 Mayu Shibazaki Remedy for erection failure comprising fused pyridazine compound
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
MXPA05001859A (es) * 2002-08-16 2005-06-03 Johnson & Johnson Compuestos de piperidinilo que se unen selectivamente a las integrinas.
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
WO2007025177A2 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
CA2635439A1 (en) * 2006-01-27 2007-08-02 Pfizer Products Inc. Aminophthalazine derivative compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US8247442B2 (en) 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
KR101167774B1 (ko) 2007-08-07 2012-07-24 에프. 호프만-라 로슈 아게 Ｎｋ3 수용체 길항제로서의 피롤리딘 아릴-에터
EP2190815B1 (en) 2007-08-22 2011-08-10 F. Hoffmann-La Roche AG Pyrrolidine aryl-ether as nk3 receptor antagonists
WO2009033995A1 (en) * 2007-09-14 2009-03-19 F. Hoffmann-La Roche Ag Piperidine derivatives as nk3 receptor antagonists
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
SU862826A3 (ru) 1981-09-07
PL116437B1 (en) 1981-06-30
AT362792B (de) 1981-06-10
ATA400878A (de) 1980-11-15
SE7806519L (sv) 1978-12-04
DK248078A (da) 1978-12-04
IT1094944B (it) 1985-08-10
FR2392986B1 (nl) 1982-07-16
IN148482B (nl) 1981-03-07
DD137355A5 (de) 1979-08-29
IN149550B (nl) 1982-01-16
JPS5416488A (en) 1979-02-07
IN149973B (nl) 1982-06-19
NZ187453A (en) 1980-12-19
IL54842A0 (en) 1978-08-31
FI781753A (fi) 1978-12-04
ATA305080A (de) 1980-12-15
AU505373B1 (en) 1979-11-15
LU79761A1 (fr) 1980-01-22
SU856383A3 (ru) 1981-08-15
ES470470A1 (es) 1979-09-01
IT7824106A0 (it) 1978-06-01
PL113208B1 (en) 1980-11-29
PT68126A (en) 1978-07-01
AT363096B (de) 1981-07-10
PL116420B1 (en) 1981-06-30
FR2392986A1 (fr) 1978-12-29
GB2000136A (en) 1979-01-04
DE2824064A1 (de) 1978-12-14
US4289772A (en) 1981-09-15
ZA783183B (en) 1979-06-27
GR74402B (nl) 1984-06-28
NO781935L (no) 1978-12-05
AR223999A1 (es) 1981-10-15
ES478200A1 (es) 1980-01-01
ES478201A1 (es) 1980-02-01
HU179745B (en) 1982-12-28
BE867727A (fr) 1978-12-01
CA1111850A (en) 1981-11-03
NL7806016A (nl) 1978-12-05
ES478199A1 (es) 1980-01-16
AR222013A1 (es) 1981-04-15
GB2000136B (en) 1982-01-06
PL207337A1 (pl) 1979-06-04
JPS5538351B2 (nl) 1980-10-03
IL54842A (en) 1982-01-31

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