BE867727A - Nouveaux composes de phtalazine et composition pharmaceutique les contenant - Google Patents

Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Info

Publication number
BE867727A
BE867727A BE188257A BE188257A BE867727A BE 867727 A BE867727 A BE 867727A BE 188257 A BE188257 A BE 188257A BE 188257 A BE188257 A BE 188257A BE 867727 A BE867727 A BE 867727A
Authority
BE
Belgium
Prior art keywords
phtalazine
compounds
new
pharmaceutical composition
composition containing
Prior art date
Application number
BE188257A
Other languages
English (en)
French (fr)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE867727A publication Critical patent/BE867727A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE188257A 1977-06-03 1978-06-01 Nouveaux composes de phtalazine et composition pharmaceutique les contenant BE867727A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (1)

Publication Number Publication Date
BE867727A true BE867727A (fr) 1978-12-01

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
BE188257A BE867727A (fr) 1977-06-03 1978-06-01 Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Country Status (29)

Country Link
US (1) US4289772A (en, 2012)
JP (1) JPS5416488A (en, 2012)
AR (2) AR222013A1 (en, 2012)
AT (2) AT362792B (en, 2012)
AU (1) AU505373B1 (en, 2012)
BE (1) BE867727A (en, 2012)
CA (1) CA1111850A (en, 2012)
DD (1) DD137355A5 (en, 2012)
DE (1) DE2824064A1 (en, 2012)
DK (1) DK248078A (en, 2012)
EG (1) EG13527A (en, 2012)
ES (4) ES470470A1 (en, 2012)
FI (1) FI781753A7 (en, 2012)
FR (1) FR2392986A1 (en, 2012)
GB (1) GB2000136B (en, 2012)
GR (1) GR74402B (en, 2012)
HU (1) HU179745B (en, 2012)
IL (1) IL54842A (en, 2012)
IN (3) IN148482B (en, 2012)
IT (1) IT1094944B (en, 2012)
LU (1) LU79761A1 (en, 2012)
NL (1) NL7806016A (en, 2012)
NO (1) NO781935L (en, 2012)
NZ (1) NZ187453A (en, 2012)
PL (3) PL116420B1 (en, 2012)
PT (1) PT68126A (en, 2012)
SE (1) SE7806519L (en, 2012)
SU (2) SU856383A3 (en, 2012)
ZA (1) ZA783183B (en, 2012)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PL128510B1 (en) * 1980-03-01 1984-02-29 Wyeth John & Brother Ltd Method of obtaining new piperidine derivatives
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
US5728712A (en) * 1995-05-19 1998-03-17 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
CN1121220C (zh) * 1996-08-20 2003-09-17 卫材株式会社 稠合哒嗪系化合物的勃起机能不全症治疗剂
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
US20040224986A1 (en) 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
BR0313534A (pt) * 2002-08-16 2005-07-12 Janssen Pharmaceutica Nv Antagonistas de integrinade ácido carboxìlico de piperidinoìla
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
JP2009524637A (ja) * 2006-01-27 2009-07-02 ファイザー・プロダクツ・インク アミノフタラジン誘導体化合物
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
ES2367464T3 (es) 2007-08-07 2011-11-03 F. Hoffmann-La Roche Ag Pirrolidina-aril-éteres como antagonistas de receptor de nk3.
CN101861302A (zh) 2007-08-22 2010-10-13 弗·哈夫曼-拉罗切有限公司 作为nk3受体拮抗剂的吡咯烷芳基-醚
EP2200982B1 (en) * 2007-09-14 2012-03-14 F. Hoffmann-La Roche AG Piperidine derivatives as nk3 receptor antagonists
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP4229828A4 (en) 2020-10-13 2024-08-28 Endeavor Biomedicines, Inc. METHODS OF TREATMENT OF FIBROSIS
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
NL7806016A (nl) 1978-12-05
NO781935L (no) 1978-12-05
ES478201A1 (es) 1980-02-01
ATA305080A (de) 1980-12-15
AR222013A1 (es) 1981-04-15
NZ187453A (en) 1980-12-19
IL54842A (en) 1982-01-31
FI781753A7 (fi) 1978-12-04
CA1111850A (en) 1981-11-03
PL116420B1 (en) 1981-06-30
SE7806519L (sv) 1978-12-04
ES470470A1 (es) 1979-09-01
IL54842A0 (en) 1978-08-31
PL113208B1 (en) 1980-11-29
GR74402B (en, 2012) 1984-06-28
EG13527A (en) 1981-12-31
ES478199A1 (es) 1980-01-16
IN149550B (en, 2012) 1982-01-16
LU79761A1 (fr) 1980-01-22
JPS5416488A (en) 1979-02-07
ES478200A1 (es) 1980-01-01
AT363096B (de) 1981-07-10
DE2824064A1 (de) 1978-12-14
IN148482B (en, 2012) 1981-03-07
GB2000136A (en) 1979-01-04
AR223999A1 (es) 1981-10-15
IN149973B (en, 2012) 1982-06-19
PT68126A (en) 1978-07-01
IT7824106A0 (it) 1978-06-01
PL116437B1 (en) 1981-06-30
ATA400878A (de) 1980-11-15
FR2392986B1 (en, 2012) 1982-07-16
US4289772A (en) 1981-09-15
SU856383A3 (ru) 1981-08-15
DD137355A5 (de) 1979-08-29
DK248078A (da) 1978-12-04
ZA783183B (en) 1979-06-27
GB2000136B (en) 1982-01-06
AT362792B (de) 1981-06-10
AU505373B1 (en) 1979-11-15
IT1094944B (it) 1985-08-10
JPS5538351B2 (en, 2012) 1980-10-03
FR2392986A1 (fr) 1978-12-29
PL207337A1 (pl) 1979-06-04
HU179745B (en) 1982-12-28
SU862826A3 (ru) 1981-09-07

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