ES472290A1 - Un procedimiento para preparar un compuesto de benceno di- sustituido en orto - Google Patents

Un procedimiento para preparar un compuesto de benceno di- sustituido en orto

Info

Publication number
ES472290A1
ES472290A1 ES472290A ES472290A ES472290A1 ES 472290 A1 ES472290 A1 ES 472290A1 ES 472290 A ES472290 A ES 472290A ES 472290 A ES472290 A ES 472290A ES 472290 A1 ES472290 A1 ES 472290A1
Authority
ES
Spain
Prior art keywords
carbon atoms
group containing
therapy
alkyl group
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472290A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Kabi AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi AB filed Critical Kabi AB
Publication of ES472290A1 publication Critical patent/ES472290A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof

Abstract

Un procedimiento para preparar un compuesto de benceno disustituido en orto, caracterizado por el hecho de que un compuesto de la fórmula general: **(Fórmula)** en la que R1 y R2 representan cada uno de ellos independientemente un grupo alcohilo que contiene 1 a 4 átomos de carbono o un grupo alcoxi que contiene 1 a 3 átomos de carbono, halógeno, R3 representa hidrógeno, halógeno, un grupo alcohilo que contiene 1 a 4 átomos de carbono, un grupo alcoxi que contiene 1 a 3 átomos de carbono, un grupo amino o un grupo nitro, A representa -SO2NR4, que está unido al anillo de benceno por su átomo de azufre o de nitrógeno y en el que R4 es hidrógeno o un grupo alcohilo que contiene 1 a 4 átomos de carbono.
ES472290A 1977-08-05 1978-08-02 Un procedimiento para preparar un compuesto de benceno di- sustituido en orto Expired ES472290A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3294677 1977-08-05

Publications (1)

Publication Number Publication Date
ES472290A1 true ES472290A1 (es) 1979-02-16

Family

ID=10346357

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472290A Expired ES472290A1 (es) 1977-08-05 1978-08-02 Un procedimiento para preparar un compuesto de benceno di- sustituido en orto

Country Status (12)

Country Link
US (1) US4218476A (es)
EP (1) EP0000826A1 (es)
JP (1) JPS5444635A (es)
AU (1) AU3857778A (es)
DK (1) DK340178A (es)
ES (1) ES472290A1 (es)
FI (1) FI782383A (es)
IT (1) IT1099585B (es)
NO (1) NO782650L (es)
NZ (1) NZ188038A (es)
PT (1) PT68382A (es)
ZA (1) ZA784348B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396628A (en) * 1981-06-18 1983-08-02 The United States Of America As Represented By The Department Of Health & Human Services Antiviral activities of dansylcadaverine and closely related compounds
US5185149A (en) * 1987-03-27 1993-02-09 Merck & Co., Inc. Methods for thrombolytic therapy
US4968494A (en) * 1987-03-27 1990-11-06 Merck & Co., Inc. Methods and compositions for thrombolytic therapy
EP0294016A3 (en) * 1987-03-27 1991-06-26 Merck & Co. Inc. Factor xiiia inhibitor compounds useful for thrombolytic therapy
DE3821540A1 (de) * 1988-06-25 1989-12-28 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung sowie solche sulfonamide enthaltende arzneimittel
US4968713A (en) * 1989-07-31 1990-11-06 Merck & Co., Inc. Certain imidazole compounds as transglutaminase inhibitors
US5077285A (en) * 1989-07-31 1991-12-31 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5030644A (en) * 1989-07-31 1991-07-09 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5019572A (en) * 1990-02-07 1991-05-28 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5021440A (en) * 1989-07-31 1991-06-04 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5047416A (en) * 1989-07-31 1991-09-10 Merck & Co., Inc. Triazole compounds and their use as transglutaminase inhibitors
RU2662308C1 (ru) * 2017-12-25 2018-07-25 Феркат Адельзянович Халиуллин Средство для лечения и профилактики тромбоза

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1238350A (fr) * 1959-06-30 1960-08-12 Inst Nat Rech Chimique Procédé d'obtention d'amines sulfurées
US3895010A (en) * 1972-12-13 1975-07-15 Dow Chemical Co 1-(Arylthio)methanesulfonamides
JPS5829784B2 (ja) * 1975-08-22 1983-06-24 萬有製薬株式会社 オメガ − （ アリ−ルスルホンアミド ）− アルキルアミンノ セイホウ
US4098889A (en) * 1977-09-01 1978-07-04 The Dow Chemical Company Antithrombotic 2-(aminoalkylthio)-N,N'-p-phenylenebissulfonamides

Also Published As

Publication number Publication date
US4218476A (en) 1980-08-19
PT68382A (en) 1978-09-01
DK340178A (da) 1979-02-06
JPS5444635A (en) 1979-04-09
NZ188038A (en) 1981-02-11
IT1099585B (it) 1985-09-18
FI782383A (fi) 1979-02-06
AU3857778A (en) 1980-02-07
EP0000826A1 (en) 1979-02-21
NO782650L (no) 1979-02-06
IT7826405A0 (it) 1978-08-02
ZA784348B (en) 1979-07-25

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