ES456622A1 - Procedimiento para la preparacion de heterociclos aminoalco-hilicos. - Google Patents
Procedimiento para la preparacion de heterociclos aminoalco-hilicos.Info
- Publication number
- ES456622A1 ES456622A1 ES456622A ES456622A ES456622A1 ES 456622 A1 ES456622 A1 ES 456622A1 ES 456622 A ES456622 A ES 456622A ES 456622 A ES456622 A ES 456622A ES 456622 A1 ES456622 A1 ES 456622A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- aminoalco
- heterocicles
- hilic
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002013 hydrophilic interaction chromatography Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 methylenedioxy Chemical group 0.000 abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Laminated Bodies (AREA)
- Nonwoven Fabrics (AREA)
- Hydrogenated Pyridines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762609645 DE2609645A1 (de) | 1976-03-09 | 1976-03-09 | Aminoalkylheterocyclen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456622A1 true ES456622A1 (es) | 1978-03-16 |
Family
ID=5971857
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456622A Expired ES456622A1 (es) | 1976-03-09 | 1977-03-08 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
| ES466598A Expired ES466598A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466599A Expired ES466599A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466601A Expired ES466601A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
| ES466602A Expired ES466602A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466605A Expired ES466605A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466603A Expired ES466603A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
| ES466606A Expired ES466606A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466604A Expired ES466604A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466600A Expired ES466600A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
Family Applications After (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466598A Expired ES466598A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466599A Expired ES466599A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466601A Expired ES466601A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
| ES466602A Expired ES466602A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466605A Expired ES466605A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466603A Expired ES466603A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
| ES466606A Expired ES466606A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466604A Expired ES466604A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
| ES466600A Expired ES466600A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
Country Status (36)
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
| DE2644833A1 (de) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung |
| DE2833140A1 (de) * | 1978-07-28 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue n-substituierte heterocyclen |
| FR2455587A1 (fr) | 1979-05-04 | 1980-11-28 | Continental Pharma | Derives de benzimidazole, leur preparation et utilisation dans le traitement des affections cardiovasculaires et compositions les contenant |
| DE3026534A1 (de) * | 1980-07-12 | 1982-03-18 | C.H. Boehringer Sohn, 6507 Ingelheim | 3,1-benzoxazin-2-one, ihre herstellung und verwendung |
| US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| DE3325875A1 (de) * | 1983-07-18 | 1985-01-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue 1-phenylimidazolidin-2-on-derivate, ihre herstellung und verwendung |
| US4743613A (en) * | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-Ī²-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-Ī²-hydroxylase activity |
| GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
| TW203049B (enExample) * | 1990-04-13 | 1993-04-01 | Yamanouchi Pharma Co Ltd | |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective Ī²3 adrenergic agonists. |
| US5808080A (en) * | 1996-09-05 | 1998-09-15 | Eli Lilly And Company | Selective Ī²3 adrenergic agonists |
| ATE215369T1 (de) | 1996-09-05 | 2002-04-15 | Lilly Co Eli | Carbazolanaloge als selektive beta3-adrenergische agonisten |
| CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| WO2002085361A1 (en) * | 2001-04-18 | 2002-10-31 | Euro-Celtique, S.A. | Benzimidazolone compounds |
| US6828440B2 (en) | 2001-04-18 | 2004-12-07 | Euro-Celtique, S.A. | Spiroindene and spiroindane compounds |
| RU2426730C2 (ru) * | 2001-04-18 | 2011-08-20 | ŠŃŠ¾-Š”ŠµŠ»ŃŠøŠŗ, Š”.Š. | ŠŠ½Š°Š»Š¾Š³Šø Š½Š¾ŃŠøŃŠµŠæŃŠøŠ½Š° |
| IL158484A0 (en) | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Nociceptin analogs |
| AU2002303406B2 (en) | 2001-04-18 | 2006-03-30 | Euro-Celtique S.A. | Nociceptin analogs |
| IL158485A0 (en) | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Spiropyrazole compounds |
| US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| AU2003297562A1 (en) * | 2002-11-27 | 2004-06-23 | Artesian Therapeutics, Inc. | COMPOUNDS WITH MIXED PDE-INHIBITORY AND Beta-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE |
| AU2003300297A1 (en) * | 2002-12-23 | 2004-07-22 | Artesian Therapeutics, Inc. | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST Beta-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE |
| DE102004001413A1 (de) * | 2004-01-09 | 2005-08-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Hydroxymethyl-4-Hydroxy-Phenyl-Derivate zur Behandlung von chronisch obstruktiver Lungenerkrankung |
| DE102004003428A1 (de) * | 2004-01-23 | 2005-08-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel |
| US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
| DE102004021779A1 (de) * | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
| US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
| DE102004045648A1 (de) * | 2004-09-21 | 2006-03-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Betamimetika zur Behandlung von Atemwegserkrankungen |
| EP1833480A2 (en) * | 2004-11-30 | 2007-09-19 | Artesian Therapeutics, Inc. | Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase |
| JP2008521806A (ja) * | 2004-11-30 | 2008-06-26 | ć¢ć¼ćć·ć¢ć³ ć»ć©ćć„ć¼ćć£ćÆć¹ļ¼ ć¤ć³ć³ć¼ćć¬ć¤ććć | åæäøå Øćę²»ēććććć®ę··ååć®ļ¼°ļ¼¤ļ¼„āé»å®³ę“»ę§ććć³Ī²āć¢ćć¬ććŖć³ä½ēØę§ć¢ć³ćæć“ćć¹ćę“»ę§ć¾ććÆéØåć¢ć“ćć¹ćę“»ę§ćęććååē© |
| DE102005007654A1 (de) * | 2005-02-19 | 2006-08-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
| DE102005030733A1 (de) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
| ES2530991T3 (es) * | 2005-08-15 | 2015-03-09 | Boehringer Ingelheim Int | Procedimiento para la obtenciĆ³n de betamimĆ©ticos |
| DE102005052127A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052102A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102005052101A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| CA2642239A1 (en) * | 2006-02-16 | 2007-08-23 | Boehringer Ingelheim International Gmbh | Drug combinations for the treatment of respiratory tract diseases |
| PE20080142A1 (es) * | 2006-03-15 | 2008-04-14 | Boehringer Ingelheim Int | Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion |
| ATE505193T1 (de) | 2006-08-07 | 2011-04-15 | Boehringer Ingelheim Int | Arzneimittelkombinationen zur behandlung von atemwegserkrankungen |
| US9604926B2 (en) | 2007-08-16 | 2017-03-28 | The University Of Mississippi | Highly selective sigma receptor radioligands |
| US8686008B2 (en) * | 2007-08-16 | 2014-04-01 | The University Of Mississippi | Highly selective sigma receptor ligands |
| WO2009026227A2 (en) * | 2007-08-16 | 2009-02-26 | The University Of Mississippi | Highly selective sigma receptor ligands |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA631296A (en) * | 1961-11-21 | Merck And Co. | Substituted benzimidazolones | |
| CH149009A (de) * | 1929-08-10 | 1931-08-15 | Chem Ind Basel | Verfahren zur Darstellung einer N-substituierten Verbindung der Pyridonreihe. |
| US2857394A (en) * | 1957-05-10 | 1958-10-21 | Ciba Pharm Prod Inc | Heterocyclic compounds |
| NL284529A (enExample) * | 1961-10-24 | |||
| FR1516714A (fr) * | 1962-11-07 | 1968-02-05 | Bayer Ag | ProcƩdƩ de prƩparation de dƩrivƩs de l'imidazolidine |
| FR1384708A (fr) * | 1963-11-21 | 1965-01-08 | Thomson Houston Comp Francaise | Perfectionnements aux dispositifs de mise en place d'objets |
| BE659364A (enExample) * | 1964-02-05 | |||
| US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
| FR1573739A (enExample) * | 1968-07-26 | 1969-07-04 | ||
| US3984405A (en) * | 1971-06-28 | 1976-10-05 | E. R. Squibb & Sons, Inc. | Anti-inflammatory agents |
| BE787103A (fr) * | 1971-08-04 | 1973-02-02 | Pfizer | Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant |
| FR2168140A1 (en) * | 1972-01-17 | 1973-08-31 | Bellon Labor Sa Roger | Dihydro-benzoxazine derivs - antidepressants |
| US3925383A (en) * | 1972-12-08 | 1975-12-09 | Janssen Pharmaceutica Nv | Bicyclic imidazoles and pyrimidines |
| US3994901A (en) * | 1974-06-13 | 1976-11-30 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
| US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
| DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
-
1976
- 1976-03-09 DE DE19762609645 patent/DE2609645A1/de not_active Withdrawn
-
1977
- 1977-02-22 SU SU772453505A patent/SU698530A3/ru active
- 1977-02-23 FI FI770586A patent/FI69070C/fi not_active IP Right Cessation
- 1977-02-24 AT AT122377A patent/AT360542B/de not_active IP Right Cessation
- 1977-03-01 RO RO7789565A patent/RO70569A/ro unknown
- 1977-03-01 RO RO7796539A patent/RO76589A/ro unknown
- 1977-03-01 RO RO77101591A patent/RO79706A/ro unknown
- 1977-03-02 US US05/773,394 patent/US4154829A/en not_active Expired - Lifetime
- 1977-03-03 MX MX775497U patent/MX4878E/es unknown
- 1977-03-04 CS CS775352A patent/CS220320B2/cs unknown
- 1977-03-04 CS CS771476A patent/CS209435B2/cs unknown
- 1977-03-07 DD DD7700197718A patent/DD130037A5/xx unknown
- 1977-03-07 NL NL7702403A patent/NL7702403A/xx not_active Application Discontinuation
- 1977-03-07 BG BG036628A patent/BG28051A4/xx unknown
- 1977-03-07 CH CH281977A patent/CH630358A5/de not_active IP Right Cessation
- 1977-03-07 LU LU76898A patent/LU76898A1/xx unknown
- 1977-03-07 BG BG036629A patent/BG28052A4/xx unknown
- 1977-03-07 BG BG035601A patent/BG27743A3/xx unknown
- 1977-03-08 IL IL51627A patent/IL51627A/xx unknown
- 1977-03-08 NZ NZ183536A patent/NZ183536A/xx unknown
- 1977-03-08 NO NO770804A patent/NO147950C/no unknown
- 1977-03-08 GR GR52928A patent/GR64553B/el unknown
- 1977-03-08 YU YU00623/77A patent/YU62377A/xx unknown
- 1977-03-08 PL PL1977215210A patent/PL112937B1/pl unknown
- 1977-03-08 DK DK102177A patent/DK102177A/da not_active Application Discontinuation
- 1977-03-08 ES ES456622A patent/ES456622A1/es not_active Expired
- 1977-03-08 PT PT66282A patent/PT66282B/pt unknown
- 1977-03-08 JP JP2532377A patent/JPS52108970A/ja active Pending
- 1977-03-08 CA CA273,388A patent/CA1086317A/en not_active Expired
- 1977-03-08 BE BE175593A patent/BE852223A/xx not_active IP Right Cessation
- 1977-03-08 HU HU77BO1653A patent/HU177953B/hu unknown
- 1977-03-08 IE IE507/77A patent/IE45300B1/en unknown
- 1977-03-08 AU AU23009/77A patent/AU515953B2/en not_active Expired
- 1977-03-08 PL PL1977196505A patent/PL111240B1/pl unknown
- 1977-03-08 ZA ZA00771412A patent/ZA771412B/xx unknown
- 1977-03-08 SE SE7702609A patent/SE435059B/xx not_active IP Right Cessation
- 1977-03-09 PH PH19550A patent/PH16110A/en unknown
- 1977-03-09 GB GB9952/77A patent/GB1571231A/en not_active Expired
- 1977-03-09 FR FR7707018A patent/FR2343731A1/fr active Granted
- 1977-11-16 SU SU772541704A patent/SU676163A3/ru active
- 1977-11-16 SU SU772542149A patent/SU685149A3/ru active
- 1977-11-16 SU SU772543651A patent/SU683616A3/ru active
-
1978
- 1978-02-01 FR FR7802775A patent/FR2372810A1/fr active Granted
- 1978-02-03 ES ES466598A patent/ES466598A1/es not_active Expired
- 1978-02-03 ES ES466599A patent/ES466599A1/es not_active Expired
- 1978-02-03 ES ES466601A patent/ES466601A1/es not_active Expired
- 1978-02-03 ES ES466602A patent/ES466602A1/es not_active Expired
- 1978-02-03 ES ES466605A patent/ES466605A1/es not_active Expired
- 1978-02-03 ES ES466603A patent/ES466603A1/es not_active Expired
- 1978-02-03 ES ES466606A patent/ES466606A1/es not_active Expired
- 1978-02-03 ES ES466604A patent/ES466604A1/es not_active Expired
- 1978-02-03 ES ES466600A patent/ES466600A1/es not_active Expired
- 1978-06-14 BG BG036630A patent/BG28053A4/xx unknown
-
1979
- 1979-04-03 US US06/026,608 patent/US4215119A/en not_active Expired - Lifetime
- 1979-12-13 US US06/102,904 patent/US4271158A/en not_active Expired - Lifetime
-
1980
- 1980-07-11 PH PH24278A patent/PH16149A/en unknown
- 1980-12-22 US US06/218,786 patent/US4363814A/en not_active Expired - Fee Related
-
1981
- 1981-01-23 PH PH25130A patent/PH17635A/en unknown
- 1981-04-30 CH CH284781A patent/CH630360A5/de not_active IP Right Cessation
- 1981-04-30 CH CH285281A patent/CH630365A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284981A patent/CH630362A5/de not_active IP Right Cessation
- 1981-04-30 CH CH285081A patent/CH630363A5/de not_active IP Right Cessation
- 1981-04-30 CH CH285181A patent/CH630364A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284681A patent/CH630359A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284881A patent/CH630361A5/de not_active IP Right Cessation
-
1983
- 1983-09-01 SG SG555/83A patent/SG55583G/en unknown
-
1984
- 1984-02-16 HK HK128/84A patent/HK12884A/xx unknown
-
1985
- 1985-06-12 JP JP60126401A patent/JPS6172A/ja active Pending
- 1985-12-30 MY MY79/85A patent/MY8500079A/xx unknown
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