ES452986A1 - Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico). - Google Patents
Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico).Info
- Publication number
- ES452986A1 ES452986A1 ES452986A ES452986A ES452986A1 ES 452986 A1 ES452986 A1 ES 452986A1 ES 452986 A ES452986 A ES 452986A ES 452986 A ES452986 A ES 452986A ES 452986 A1 ES452986 A1 ES 452986A1
- Authority
- ES
- Spain
- Prior art keywords
- dihydropyridine
- preparation
- therapeutic agent
- dicarboxylic acid
- acid diester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2549568A DE2549568C3 (de) | 1975-11-05 | 1975-11-05 | 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES452986A1 true ES452986A1 (es) | 1977-12-16 |
Family
ID=5960951
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES452986A Expired ES452986A1 (es) | 1975-11-05 | 1976-11-04 | Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico). |
ES463166A Expired ES463166A1 (es) | 1975-11-05 | 1977-10-13 | Procedimiento para preparar ester isobutilico del acido 2,6-dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1,4-dihidropiri- din-5-carboxilico. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES463166A Expired ES463166A1 (es) | 1975-11-05 | 1977-10-13 | Procedimiento para preparar ester isobutilico del acido 2,6-dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1,4-dihidropiri- din-5-carboxilico. |
Country Status (27)
Country | Link |
---|---|
JP (1) | JPS5259161A (cs) |
AT (1) | AT352129B (cs) |
AU (1) | AU498964B2 (cs) |
BE (1) | BE847968A (cs) |
BG (6) | BG24804A3 (cs) |
CA (1) | CA1085406A (cs) |
CH (2) | CH623038A5 (cs) |
CS (1) | CS200499B2 (cs) |
DE (1) | DE2549568C3 (cs) |
DK (1) | DK146762C (cs) |
ES (2) | ES452986A1 (cs) |
FI (1) | FI60704C (cs) |
FR (1) | FR2330395A1 (cs) |
GB (1) | GB1516793A (cs) |
GR (1) | GR61241B (cs) |
HK (1) | HK12681A (cs) |
IE (1) | IE43984B1 (cs) |
IL (1) | IL50817A (cs) |
LU (2) | LU88275I2 (cs) |
NL (2) | NL175915C (cs) |
NO (1) | NO145574C (cs) |
NZ (1) | NZ182502A (cs) |
PL (2) | PL106084B1 (cs) |
PT (1) | PT65797B (cs) |
RO (1) | RO70295A (cs) |
SE (1) | SE423542B (cs) |
ZA (1) | ZA766622B (cs) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
JPS55301A (en) * | 1978-02-14 | 1980-01-05 | Yamanouchi Pharmaceut Co Ltd | 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation |
DE3212736A1 (de) * | 1982-04-06 | 1983-10-13 | Bayer Ag, 5090 Leverkusen | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung |
DE3222367A1 (de) * | 1982-06-15 | 1983-12-15 | Bayer Ag, 5090 Leverkusen | Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung |
JPS5982192U (ja) * | 1982-11-27 | 1984-06-02 | エムケ−精工株式会社 | 扉 |
DE3312216A1 (de) * | 1983-04-05 | 1984-10-11 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern |
DE3312283A1 (de) * | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
-
1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/de not_active Expired
-
1976
- 1976-10-22 NO NO763608A patent/NO145574C/no unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/ja active Granted
- 1976-11-01 BG BG7600035344A patent/BG24804A3/xx unknown
- 1976-11-01 BG BG7600035342A patent/BG25079A3/xx unknown
- 1976-11-01 BG BG7600035345A patent/BG24805A3/xx unknown
- 1976-11-01 BG BG7600034575A patent/BG24668A3/xx unknown
- 1976-11-01 BG BG7600035343A patent/BG24803A3/xx unknown
- 1976-11-01 BG BG7600035341A patent/BG25078A3/xx unknown
- 1976-11-02 IL IL50817A patent/IL50817A/xx unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 CH CH1381976A patent/CH623038A5/de not_active IP Right Cessation
- 1976-11-02 CS CS767068A patent/CS200499B2/cs unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/xx unknown
- 1976-11-02 RO RO7688294A patent/RO70295A/ro unknown
- 1976-11-03 FI FI763160A patent/FI60704C/fi not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/pl unknown
- 1976-11-03 PL PL1976201800A patent/PL105940B1/pl unknown
- 1976-11-03 AT AT814276A patent/AT352129B/de not_active IP Right Cessation
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/xx not_active IP Right Cessation
- 1976-11-04 PT PT65797A patent/PT65797B/pt unknown
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 DK DK498476A patent/DK146762C/da not_active IP Right Cessation
- 1976-11-04 ES ES452986A patent/ES452986A1/es not_active Expired
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 ZA ZA766622A patent/ZA766622B/xx unknown
- 1976-11-04 BE BE172063A patent/BE847968A/xx not_active IP Right Cessation
- 1976-11-04 SE SE7612308A patent/SE423542B/xx not_active IP Right Cessation
- 1976-11-04 GR GR52093A patent/GR61241B/el unknown
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-05 FR FR7633488A patent/FR2330395A1/fr active Granted
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
-
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/es not_active Expired
-
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/de not_active IP Right Cessation
-
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/xx unknown
-
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/nl unknown
Also Published As
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