ES2913071T3 - Forma sólida de 1-etil-7-(2-metil-6-(1H-1,2,4-triazol-3-il)piridina-3-il)-3,4-dihidropirazino[2,3-B]pirazin-2(1H)-ona, composiciones de la misma y procedimientos de uso - Google Patents
Forma sólida de 1-etil-7-(2-metil-6-(1H-1,2,4-triazol-3-il)piridina-3-il)-3,4-dihidropirazino[2,3-B]pirazin-2(1H)-ona, composiciones de la misma y procedimientos de uso Download PDFInfo
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- ES2913071T3 ES2913071T3 ES15780615T ES15780615T ES2913071T3 ES 2913071 T3 ES2913071 T3 ES 2913071T3 ES 15780615 T ES15780615 T ES 15780615T ES 15780615 T ES15780615 T ES 15780615T ES 2913071 T3 ES2913071 T3 ES 2913071T3
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461980108P | 2014-04-16 | 2014-04-16 | |
| US201462003173P | 2014-05-27 | 2014-05-27 | |
| PCT/US2015/025850 WO2015160875A1 (en) | 2014-04-16 | 2015-04-15 | SOLID FORMS OF 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-b]PYRAZIN-2(1H)-ONE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2913071T3 true ES2913071T3 (es) | 2022-05-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15780615T Active ES2913071T3 (es) | 2014-04-16 | 2015-04-15 | Forma sólida de 1-etil-7-(2-metil-6-(1H-1,2,4-triazol-3-il)piridina-3-il)-3,4-dihidropirazino[2,3-B]pirazin-2(1H)-ona, composiciones de la misma y procedimientos de uso |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9416134B2 (enExample) |
| EP (1) | EP3131553B1 (enExample) |
| JP (3) | JP6787791B2 (enExample) |
| CA (2) | CA2945960C (enExample) |
| ES (1) | ES2913071T3 (enExample) |
| MX (2) | MX370786B (enExample) |
| NZ (1) | NZ714742A (enExample) |
| WO (1) | WO2015160875A1 (enExample) |
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| NZ629411A (en) * | 2013-04-17 | 2017-06-30 | Signal Pharm Llc | Treatment of cancer with dihydropyrazino-pyrazines |
| SG11201508527VA (en) * | 2013-04-17 | 2015-11-27 | Signal Pharm Llc | Pharmaceutical formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl) -3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one |
| EP3641772B1 (en) | 2017-06-22 | 2023-08-02 | Celgene Corporation | Treatment of hepatocellular carcinoma characterized by hepatitis b virus infection |
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| US3567725A (en) | 1968-11-20 | 1971-03-02 | Merck & Co Inc | Process for preparation of 1h-imidazo-(4,5-b)pyrazin-2-ones |
| US4294837A (en) | 1980-03-28 | 1981-10-13 | Sterling Drug Inc. | 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use |
| US4294836A (en) | 1980-03-24 | 1981-10-13 | Sterling Drug Inc. | 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]-pyridine-2-thiones and their cardiotonic use |
| US4317909A (en) | 1980-03-24 | 1982-03-02 | Sterling Drug Inc. | Preparation of 1,3-dihydro-5-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones |
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| DD262026A1 (de) | 1987-07-10 | 1988-11-16 | Akad Wissenschaften Ddr | Verfahren zur herstellung von 4-substituierten 6-(pyrid-4-yl)-2,4-dihydro-1h-imidazo[4,5-b]pyrid-2-onen |
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2014
- 2014-09-03 NZ NZ714742A patent/NZ714742A/en unknown
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2015
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- 2015-04-15 ES ES15780615T patent/ES2913071T3/es active Active
- 2015-04-15 CA CA2945960A patent/CA2945960C/en active Active
- 2015-04-15 JP JP2016562778A patent/JP6787791B2/ja active Active
- 2015-04-15 EP EP15780615.9A patent/EP3131553B1/en active Active
- 2015-04-15 CA CA3164682A patent/CA3164682A1/en active Pending
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2019
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2020
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| JP2019116491A (ja) | 2019-07-18 |
| CA3164682A1 (en) | 2015-10-22 |
| JP2021054844A (ja) | 2021-04-08 |
| US9416134B2 (en) | 2016-08-16 |
| MX2016013436A (es) | 2017-02-15 |
| EP3131553A4 (en) | 2017-09-06 |
| JP6787791B2 (ja) | 2020-11-18 |
| NZ629877A (en) | 2015-12-24 |
| US9981971B2 (en) | 2018-05-29 |
| MX370786B (es) | 2020-01-06 |
| EP3131553A1 (en) | 2017-02-22 |
| EP3131553B1 (en) | 2022-02-23 |
| US20160318940A1 (en) | 2016-11-03 |
| CA2945960A1 (en) | 2015-10-22 |
| CA2945960C (en) | 2022-08-30 |
| WO2015160875A1 (en) | 2015-10-22 |
| MX2019006605A (es) | 2019-08-21 |
| NZ714742A (en) | 2017-04-28 |
| JP2017511361A (ja) | 2017-04-20 |
| US20150299209A1 (en) | 2015-10-22 |
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