AR094997A1 - Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que las comprenden y sus usos - Google Patents

Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que las comprenden y sus usos

Info

Publication number
AR094997A1
AR094997A1 ARP130102836A ARP130102836A AR094997A1 AR 094997 A1 AR094997 A1 AR 094997A1 AR P130102836 A ARP130102836 A AR P130102836A AR P130102836 A ARP130102836 A AR P130102836A AR 094997 A1 AR094997 A1 AR 094997A1
Authority
AR
Argentina
Prior art keywords
oxoisoindolin
piperidin
compositions
solid forms
morfolinometil
Prior art date
Application number
ARP130102836A
Other languages
English (en)
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49054882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR094997(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of AR094997A1 publication Critical patent/AR094997A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring

Abstract

Sales y formas sólidas de la 3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-iI)piperidin-2,6-diona o un estereoisómero de éstas. También composiciones que incluyen las sales y las formas sólidas, así como sus métodos de uso. Tratamiento del cáncer. Reivindicación 1: Una forma sólida que comprende un anhidrato del compuesto de fórmula (1).
ARP130102836A 2012-08-09 2013-08-08 Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que las comprenden y sus usos AR094997A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261681484P 2012-08-09 2012-08-09

Publications (1)

Publication Number Publication Date
AR094997A1 true AR094997A1 (es) 2015-09-16

Family

ID=49054882

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130102836A AR094997A1 (es) 2012-08-09 2013-08-08 Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que las comprenden y sus usos

Country Status (37)

Country Link
US (7) US9221788B2 (es)
EP (3) EP3524598B1 (es)
JP (4) JP6419072B2 (es)
KR (1) KR20150041123A (es)
CN (2) CN104703978B (es)
AR (1) AR094997A1 (es)
AU (1) AU2013299631B2 (es)
BR (1) BR112015001874A2 (es)
CA (1) CA2878954C (es)
CL (1) CL2015000291A1 (es)
CR (1) CR20150050A (es)
CY (1) CY1121592T1 (es)
DK (1) DK2882737T3 (es)
EA (1) EA201590330A1 (es)
EC (1) ECSP15004234A (es)
ES (2) ES2723277T3 (es)
HK (1) HK1211576A1 (es)
HR (1) HRP20190398T1 (es)
HU (1) HUE042685T2 (es)
IL (1) IL236922A0 (es)
IN (1) IN2015DN00885A (es)
LT (1) LT2882737T (es)
MX (2) MX359508B (es)
NZ (1) NZ628030A (es)
PE (1) PE20150617A1 (es)
PH (1) PH12015500275A1 (es)
PL (1) PL2882737T3 (es)
PT (1) PT2882737T (es)
RS (1) RS58548B1 (es)
SA (1) SA515360022B1 (es)
SG (1) SG11201500999WA (es)
SI (1) SI2882737T1 (es)
TR (1) TR201904785T4 (es)
TW (1) TW201408657A (es)
UA (1) UA114521C2 (es)
WO (1) WO2014025964A2 (es)
ZA (1) ZA201500326B (es)

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WO2024005339A1 (ko) * 2022-06-27 2024-01-04 에이비온 주식회사 트리아졸로피라진 유도체의 캠실산염
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