ECSP15004234A - Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que comprenden y métodos para utilizar las mismas - Google Patents

Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que comprenden y métodos para utilizar las mismas

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Publication number
ECSP15004234A
ECSP15004234A ECIEPI20154234A ECPI201504234A ECSP15004234A EC SP15004234 A ECSP15004234 A EC SP15004234A EC IEPI20154234 A ECIEPI20154234 A EC IEPI20154234A EC PI201504234 A ECPI201504234 A EC PI201504234A EC SP15004234 A ECSP15004234 A EC SP15004234A
Authority
EC
Ecuador
Prior art keywords
salts
oxoisoindolin
morpholinomethyl
oxy
benzyl
Prior art date
Application number
ECIEPI20154234A
Other languages
English (en)
Inventor
John Traverse
Ying Li
Benjamin Cohen
Jean Xu
Original Assignee
Rahr Corp A Delaware Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49054882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP15004234(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rahr Corp A Delaware Corp filed Critical Rahr Corp A Delaware Corp
Publication of ECSP15004234A publication Critical patent/ECSP15004234A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring

Abstract

Se describen sales y formas sólidas de 3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona, o un estereoisómero de las mismas. También se describen composiciones que comprenden y métodos para utilizar las sales y formas sólidas.
ECIEPI20154234A 2012-08-09 2015-02-05 Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que comprenden y métodos para utilizar las mismas ECSP15004234A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261681484P 2012-08-09 2012-08-09

Publications (1)

Publication Number Publication Date
ECSP15004234A true ECSP15004234A (es) 2015-12-31

Family

ID=49054882

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI20154234A ECSP15004234A (es) 2012-08-09 2015-02-05 Sales y formas sólidas de (s)-3-(4-((4-(morfolinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidin-2,6-diona y composiciones que comprenden y métodos para utilizar las mismas

Country Status (37)

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US (7) US9221788B2 (es)
EP (3) EP3524598B1 (es)
JP (4) JP6419072B2 (es)
KR (1) KR20150041123A (es)
CN (2) CN104703978B (es)
AR (1) AR094997A1 (es)
AU (1) AU2013299631B2 (es)
BR (1) BR112015001874A2 (es)
CA (1) CA2878954C (es)
CL (1) CL2015000291A1 (es)
CR (1) CR20150050A (es)
CY (1) CY1121592T1 (es)
DK (1) DK2882737T3 (es)
EA (1) EA201590330A1 (es)
EC (1) ECSP15004234A (es)
ES (2) ES2723277T3 (es)
HK (1) HK1211576A1 (es)
HR (1) HRP20190398T1 (es)
HU (1) HUE042685T2 (es)
IL (1) IL236922A0 (es)
IN (1) IN2015DN00885A (es)
LT (1) LT2882737T (es)
MX (2) MX359508B (es)
NZ (1) NZ628030A (es)
PE (1) PE20150617A1 (es)
PH (1) PH12015500275A1 (es)
PL (1) PL2882737T3 (es)
PT (1) PT2882737T (es)
RS (1) RS58548B1 (es)
SA (1) SA515360022B1 (es)
SG (1) SG11201500999WA (es)
SI (1) SI2882737T1 (es)
TR (1) TR201904785T4 (es)
TW (1) TW201408657A (es)
UA (1) UA114521C2 (es)
WO (1) WO2014025964A2 (es)
ZA (1) ZA201500326B (es)

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