MX370786B - Formas sólidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-di-hidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de éste y métodos para su uso. - Google Patents

Formas sólidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-di-hidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de éste y métodos para su uso.

Info

Publication number
MX370786B
MX370786B MX2016013436A MX2016013436A MX370786B MX 370786 B MX370786 B MX 370786B MX 2016013436 A MX2016013436 A MX 2016013436A MX 2016013436 A MX2016013436 A MX 2016013436A MX 370786 B MX370786 B MX 370786B
Authority
MX
Mexico
Prior art keywords
methods
dihydropyrazino
pyrazin
triazol
ethyl
Prior art date
Application number
MX2016013436A
Other languages
English (en)
Spanish (es)
Other versions
MX2016013436A (es
Inventor
Lee Thomas
Boersen Nathan
Menon Anil
Eckert Jeffrey
K Parikh Darshan
Original Assignee
Signal Pharm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of MX2016013436A publication Critical patent/MX2016013436A/es
Publication of MX370786B publication Critical patent/MX370786B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2016013436A 2014-04-16 2015-04-15 Formas sólidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-di-hidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de éste y métodos para su uso. MX370786B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461980108P 2014-04-16 2014-04-16
US201462003173P 2014-05-27 2014-05-27
PCT/US2015/025850 WO2015160875A1 (en) 2014-04-16 2015-04-15 SOLID FORMS OF 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-b]PYRAZIN-2(1H)-ONE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE

Publications (2)

Publication Number Publication Date
MX2016013436A MX2016013436A (es) 2017-02-15
MX370786B true MX370786B (es) 2020-01-06

Family

ID=54321423

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016013436A MX370786B (es) 2014-04-16 2015-04-15 Formas sólidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-di-hidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de éste y métodos para su uso.
MX2019006605A MX2019006605A (es) 2014-04-16 2016-10-13 Formas solidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-dihidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de este y metodos para su uso.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019006605A MX2019006605A (es) 2014-04-16 2016-10-13 Formas solidas de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)pirid in-3-il)-3,4-dihidropirazino[2,3-b]pirazin-2(1h)-ona, composiciones de este y metodos para su uso.

Country Status (8)

Country Link
US (2) US9416134B2 (enExample)
EP (1) EP3131553B1 (enExample)
JP (3) JP6787791B2 (enExample)
CA (2) CA2945960C (enExample)
ES (1) ES2913071T3 (enExample)
MX (2) MX370786B (enExample)
NZ (1) NZ714742A (enExample)
WO (1) WO2015160875A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6382946B2 (ja) 2013-04-17 2018-08-29 シグナル ファーマシューティカルズ，エルエルシー ジヒドロピラジノ−ピラジンによる癌治療
EP3549940A1 (en) * 2013-04-17 2019-10-09 Signal Pharmaceuticals, LLC Pharmaceutical formulations, of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl) -3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one
IL271491B2 (en) 2017-06-22 2023-09-01 Celgene Corp Treatment of carcinoma of the liver characterized by hepatitis b virus infection
KR20230043910A (ko) * 2020-07-22 2023-03-31 테바 파마슈티컬스 인터내셔널 게엠베하 벨루모수딜 및 벨루모수딜 염의 고체 상태 형태

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