PL3500571T3 - Związki imidazo[1,2-a]pirydynowe, kompozycje je zawierające, sposoby leczenia chorób z ich wykorzystaniem oraz sposoby ich wytwarzania - Google Patents

Związki imidazo[1,2-a]pirydynowe, kompozycje je zawierające, sposoby leczenia chorób z ich wykorzystaniem oraz sposoby ich wytwarzania

Info

Publication number
PL3500571T3
PL3500571T3 PL17821743T PL17821743T PL3500571T3 PL 3500571 T3 PL3500571 T3 PL 3500571T3 PL 17821743 T PL17821743 T PL 17821743T PL 17821743 T PL17821743 T PL 17821743T PL 3500571 T3 PL3500571 T3 PL 3500571T3
Authority
PL
Poland
Prior art keywords
methods
imidazo
compositions
preparing
treating diseases
Prior art date
Application number
PL17821743T
Other languages
English (en)
Inventor
Daniel T. STARCZYNOWSKI
Craig J. Thomas
Garrett RHYASEN
Katelyn MELGAR
Morgan MacKenzie WALKER
Jian-kang JIANG
Original Assignee
Children's Hospital Medical Center
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Children's Hospital Medical Center, The U.S.A. As Represented By The Secretary, Department Of Health And Human Services filed Critical Children's Hospital Medical Center
Publication of PL3500571T3 publication Critical patent/PL3500571T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL17821743T 2016-08-17 2017-08-16 Związki imidazo[1,2-a]pirydynowe, kompozycje je zawierające, sposoby leczenia chorób z ich wykorzystaniem oraz sposoby ich wytwarzania PL3500571T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662375965P 2016-08-17 2016-08-17
PCT/US2017/047088 WO2018038988A2 (en) 2016-08-17 2017-08-16 Compounds, compositions, methods for treating diseases, and methods for preparing compounds
EP17821743.6A EP3500571B1 (en) 2016-08-17 2017-08-16 Imidazo[1,2-a]pyridin compounds, compositions comprising them, methods for treating diseases using them, and methods for preparing them

Publications (1)

Publication Number Publication Date
PL3500571T3 true PL3500571T3 (pl) 2021-06-28

Family

ID=60812120

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17821743T PL3500571T3 (pl) 2016-08-17 2017-08-16 Związki imidazo[1,2-a]pirydynowe, kompozycje je zawierające, sposoby leczenia chorób z ich wykorzystaniem oraz sposoby ich wytwarzania

Country Status (9)

Country Link
US (1) US20220213094A1 (pl)
EP (2) EP3500571B1 (pl)
CA (1) CA3033755A1 (pl)
DK (1) DK3500571T3 (pl)
ES (1) ES2862314T3 (pl)
LT (1) LT3500571T (pl)
PL (1) PL3500571T3 (pl)
PT (1) PT3500571T (pl)
WO (1) WO2018038988A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11542261B2 (en) * 2016-08-17 2023-01-03 Children's Hospital Medical Center Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors
AU2019401649A1 (en) 2018-12-20 2021-07-08 Incyte Corporation Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2
EP4188926A1 (en) * 2020-07-31 2023-06-07 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
JP2024501658A (ja) * 2020-12-23 2024-01-15 チルドレンズ ホスピタル メディカル センター 多環状ｉｒａｋ及びｆｌｔ３阻害化合物、並びにその使用
WO2023116888A1 (zh) * 2021-12-23 2023-06-29 杭州多域生物技术有限公司 一种五元并六元化合物、制备方法、药物组合物和应用
WO2023239941A1 (en) * 2022-06-10 2023-12-14 Interline Therapeutics Inc. Imidazo(1,2-a)pyridine derivatives as ripk2 inhibitors
WO2023250431A2 (en) * 2022-06-22 2023-12-28 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10584115B2 (en) * 2013-11-21 2020-03-10 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine BMI-1 inhibitors

Also Published As

Publication number Publication date
US20220213094A1 (en) 2022-07-07
EP3854796A1 (en) 2021-07-28
PT3500571T (pt) 2021-03-29
CA3033755A1 (en) 2018-03-01
DK3500571T3 (da) 2021-03-08
EP3500571B1 (en) 2020-12-30
ES2862314T3 (es) 2021-10-07
WO2018038988A2 (en) 2018-03-01
EP3500571A2 (en) 2019-06-26
LT3500571T (lt) 2021-04-12
WO2018038988A3 (en) 2018-04-05

Similar Documents

Publication Publication Date Title
IL266170A (en) A process for the preparation of pyrazolo[1,5-a]pyrimidines and their salts
HK1258905A1 (zh) 作為ret激酶抑制劑的取代的吡唑並[1，5-a]吡啶化合物
PT3500571T (pt) Compostos de imidazo[1,2-a] piridina, composições que os compreendem, métodos para o uso no tratamento de doenças e seus métodos de preparação
ZA201802976B (en) N-sulfonylated pyrazolo[3,4-b]pyridin-6-carboxamides and method of use
LT3107914T (lt) Pirazolo[1,5-a]pirimidin-5,7-diamino junginiai kaip cdk inhibitoriai ir jų terapinis panaudojimas
ZA201808257B (en) 1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors
HK1247203A1 (zh) 取代的咪唑並[1，2-α]吡啶-2-基胺化合物及其藥物組合物和使用方法
ZA201900236B (en) Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof
ZA201904236B (en) Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as pde1 inhibitors
HK1225723A1 (zh) 取代的咪唑並[1，2-a]吡啶甲酰胺及其用途
IL290419B (en) Imidazo[a-1,5]pyrazine derivatives as inhibitors of pi3k delta
IL265153A (en) 8-(azetidin-1-yl)-[4,2,1]triazolo[5,1-a]pyridinyl compounds, preparations and methods of use
HK1257427A1 (zh) 用於製備2-吡唑並[1，5-a]吡嗪-2-基吡啶並[1，2-a]嘧啶-4-酮的方法