LT3500571T - Imidazo[1,2-a]piridino junginiai, juos apimančios kompozicijos, ligų gydymo būdai juos panaudojant, ir jų paruošimo būdai - Google Patents

Imidazo[1,2-a]piridino junginiai, juos apimančios kompozicijos, ligų gydymo būdai juos panaudojant, ir jų paruošimo būdai

Info

Publication number
LT3500571T
LT3500571T LTEP17821743.6T LT17821743T LT3500571T LT 3500571 T LT3500571 T LT 3500571T LT 17821743 T LT17821743 T LT 17821743T LT 3500571 T LT3500571 T LT 3500571T
Authority
LT
Lithuania
Prior art keywords
methods
imidazo
compositions
preparing
treating diseases
Prior art date
Application number
LTEP17821743.6T
Other languages
English (en)
Inventor
Daniel T. STARCZYNOWSKI
Craig J. Thomas
Garrett RHYASEN
Katelyn MELGAR
Morgan MacKenzie WALKER
Jian-kang JIANG
Original Assignee
Children`S Hospital Medical Center
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Children`S Hospital Medical Center, The U.S.A. As Represented By The Secretary, Department Of Health And Human Services filed Critical Children`S Hospital Medical Center
Publication of LT3500571T publication Critical patent/LT3500571T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LTEP17821743.6T 2016-08-17 2017-08-16 Imidazo[1,2-a]piridino junginiai, juos apimančios kompozicijos, ligų gydymo būdai juos panaudojant, ir jų paruošimo būdai LT3500571T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662375965P 2016-08-17 2016-08-17
PCT/US2017/047088 WO2018038988A2 (en) 2016-08-17 2017-08-16 Compounds, compositions, methods for treating diseases, and methods for preparing compounds

Publications (1)

Publication Number Publication Date
LT3500571T true LT3500571T (lt) 2021-04-12

Family

ID=60812120

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17821743.6T LT3500571T (lt) 2016-08-17 2017-08-16 Imidazo[1,2-a]piridino junginiai, juos apimančios kompozicijos, ligų gydymo būdai juos panaudojant, ir jų paruošimo būdai

Country Status (9)

Country Link
US (1) US20220213094A1 (lt)
EP (2) EP3854796A1 (lt)
CA (1) CA3033755A1 (lt)
DK (1) DK3500571T3 (lt)
ES (1) ES2862314T3 (lt)
LT (1) LT3500571T (lt)
PL (1) PL3500571T3 (lt)
PT (1) PT3500571T (lt)
WO (1) WO2018038988A2 (lt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11542261B2 (en) * 2016-08-17 2023-01-03 Children's Hospital Medical Center Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors
MX2021007426A (es) 2018-12-20 2021-09-08 Incyte Corp Compuestos de imidazopiridazina e imidazopiridina como inhibidores de cinasa-2 de tipo receptor de activina.
EP4188926A1 (en) * 2020-07-31 2023-06-07 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
JP2024501658A (ja) * 2020-12-23 2024-01-15 チルドレンズ ホスピタル メディカル センター 多環状ｉｒａｋ及びｆｌｔ３阻害化合物、並びにその使用
WO2023116888A1 (zh) * 2021-12-23 2023-06-29 杭州多域生物技术有限公司 一种五元并六元化合物、制备方法、药物组合物和应用
WO2023239941A1 (en) * 2022-06-10 2023-12-14 Interline Therapeutics Inc. Imidazo(1,2-a)pyridine derivatives as ripk2 inhibitors
WO2023250431A2 (en) * 2022-06-22 2023-12-28 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3071553A4 (en) * 2013-11-21 2017-08-02 PTC Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors

Also Published As

Publication number Publication date
PT3500571T (pt) 2021-03-29
WO2018038988A3 (en) 2018-04-05
EP3854796A1 (en) 2021-07-28
DK3500571T3 (da) 2021-03-08
EP3500571A2 (en) 2019-06-26
PL3500571T3 (pl) 2021-06-28
EP3500571B1 (en) 2020-12-30
CA3033755A1 (en) 2018-03-01
WO2018038988A2 (en) 2018-03-01
ES2862314T3 (es) 2021-10-07
US20220213094A1 (en) 2022-07-07

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