ES2895487T3 - Método de preparación de un inhibidor de la PDE10 ópticamente activo - Google Patents
Método de preparación de un inhibidor de la PDE10 ópticamente activo Download PDFInfo
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- ES2895487T3 ES2895487T3 ES15785340T ES15785340T ES2895487T3 ES 2895487 T3 ES2895487 T3 ES 2895487T3 ES 15785340 T ES15785340 T ES 15785340T ES 15785340 T ES15785340 T ES 15785340T ES 2895487 T3 ES2895487 T3 ES 2895487T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
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| US201461985381P | 2014-04-28 | 2014-04-28 | |
| US201462047569P | 2014-09-08 | 2014-09-08 | |
| PCT/US2015/027645 WO2015167968A1 (en) | 2014-04-28 | 2015-04-24 | Optically active pde10 inhibitor |
Publications (1)
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| ES2895487T3 true ES2895487T3 (es) | 2022-02-21 |
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| ES15785340T Active ES2895487T3 (es) | 2014-04-28 | 2015-04-24 | Método de preparación de un inhibidor de la PDE10 ópticamente activo |
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| EP (1) | EP3137461B1 (enExample) |
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| KR101713453B1 (ko) * | 2010-03-12 | 2017-03-07 | 오메로스 코포레이션 | Pde10 억제제 및 관련 조성물 및 방법 |
| NZ716494A (en) * | 2014-04-28 | 2017-07-28 | Omeros Corp | Processes and intermediates for the preparation of a pde10 inhibitor |
| NZ630803A (en) * | 2014-04-28 | 2016-03-31 | Omeros Corp | Optically active pde10 inhibitor |
| US20160284909A1 (en) * | 2015-03-27 | 2016-09-29 | Gabriel Harley | Multi-diode solar cells |
| KR20170139074A (ko) * | 2015-04-24 | 2017-12-18 | 오메로스 코포레이션 | Pde10 억제제 및 관련 조성물 및 방법 |
| WO2017079678A1 (en) | 2015-11-04 | 2017-05-11 | Omeros Corporation | Solid state forms of a pde10 inhibitor |
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| PT100905A (pt) | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
| NZ257955A (en) | 1992-12-02 | 1996-05-28 | Pfizer | Catechol diethers pharmaceutical compositions |
| DE4323192A1 (de) | 1993-07-10 | 1995-01-12 | Basf Ag | Verfahren zur Herstellung von Homo- und Copolymerisaten von Alk-1-enen |
| DE4325846C1 (de) | 1993-07-31 | 1995-01-19 | Herberts Gmbh | Verwendung von Furan-modifizierten aromatischen Pinakolderivaten als Initiatoren und Furan-modifizierte aromatische Pinakolderivate als solche |
| DE4343286A1 (de) | 1993-12-17 | 1995-06-22 | Hoechst Ag | Heteroaromatische Verbindungen und ihre Verwendung in flüssigkristallinen Mischungen |
| DE4409501A1 (de) | 1994-03-19 | 1995-09-21 | Didier Werke Ag | Verschleißfutter eines Schachtofens und Stein hierfür |
| CA2193725A1 (en) | 1994-06-24 | 1996-01-04 | David Cavalla | Aryl derivative compounds and uses to inhibit phosphodiesterase iv acti vity |
| US5789434A (en) | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
| TW332201B (en) | 1995-04-06 | 1998-05-21 | Janssen Pharmaceutica Nv | 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives |
| TW424087B (en) | 1995-04-06 | 2001-03-01 | Janssen Pharmaceutica Nv | 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives |
| US6037370A (en) | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
| CN1209809A (zh) | 1996-01-22 | 1999-03-03 | 藤泽药品工业株式会社 | 新化合物 |
| AU4015497A (en) | 1996-08-26 | 1998-03-19 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Thiazole derivatives useful as selective inhibitors of pde-iv |
| JPH1087543A (ja) | 1996-09-17 | 1998-04-07 | Chisso Corp | アルコキシベンゼン誘導体、液晶組成物および液晶表示素子 |
| US6548490B1 (en) | 1997-10-28 | 2003-04-15 | Vivus, Inc. | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| WO1999045914A1 (en) | 1998-03-13 | 1999-09-16 | Maruho Kabushikikaisha | Alkyl amine derivative and local anesthetic agent using the same |
| GB9807354D0 (en) * | 1998-04-07 | 1998-06-03 | Glaxo Group Ltd | Antiviral compound |
| SE9804212D0 (sv) | 1998-12-04 | 1998-12-04 | Astra Pharma Prod | Compounds |
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2014
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- 2014-09-10 NZ NZ716462A patent/NZ716462A/en unknown
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2015
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- 2015-04-24 BR BR112016024523-7A patent/BR112016024523B1/pt active IP Right Grant
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- 2015-04-24 RU RU2016146097A patent/RU2016146097A/ru not_active Application Discontinuation
- 2015-04-24 AU AU2015253463A patent/AU2015253463B2/en active Active
- 2015-04-24 CN CN201580023106.6A patent/CN106255690B/zh active Active
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| RU2016146097A3 (enExample) | 2018-11-15 |
| AU2015253463B2 (en) | 2018-12-06 |
| CN106255690A (zh) | 2016-12-21 |
| US9850238B2 (en) | 2017-12-26 |
| AU2015253463A1 (en) | 2016-11-03 |
| US9493447B2 (en) | 2016-11-15 |
| IL248586A0 (en) | 2016-12-29 |
| EP3137461B1 (en) | 2021-08-11 |
| WO2015167968A1 (en) | 2015-11-05 |
| EP3137461A4 (en) | 2017-09-13 |
| RU2016146097A (ru) | 2018-05-30 |
| NZ716462A (en) | 2017-11-24 |
| CA2946754A1 (en) | 2015-11-05 |
| EP3137461A1 (en) | 2017-03-08 |
| KR20160141845A (ko) | 2016-12-09 |
| NZ630803A (en) | 2016-03-31 |
| JP2017513913A (ja) | 2017-06-01 |
| US20160024070A1 (en) | 2016-01-28 |
| IL248586B (en) | 2019-09-26 |
| KR102558505B1 (ko) | 2023-07-21 |
| CN106255690B (zh) | 2020-07-17 |
| CA2946754C (en) | 2022-08-30 |
| BR112016024523B1 (pt) | 2022-10-11 |
| US20170096420A1 (en) | 2017-04-06 |
| BR112016024523A2 (pt) | 2017-08-15 |
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