ES2735979T3 - Derivados de la imidazopiridina como inhibidores de tirosina quinasas receptoras - Google Patents

Derivados de la imidazopiridina como inhibidores de tirosina quinasas receptoras Download PDF

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Publication number
ES2735979T3
ES2735979T3 ES09761801T ES09761801T ES2735979T3 ES 2735979 T3 ES2735979 T3 ES 2735979T3 ES 09761801 T ES09761801 T ES 09761801T ES 09761801 T ES09761801 T ES 09761801T ES 2735979 T3 ES2735979 T3 ES 2735979T3
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group
optionally substituted
compound
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English (en)
Spanish (es)
Inventor
Valerio Berdini
Maria Carr
Miles Congreve
Martyn Frederickson
Charlotte Griffiths-Jones
Christopher Hamlett
Andrew Madin
Christopher Murray
Rajdeep Kaur Benning
Gordon Saxty
Emma Vickerstaffe
Andrew Woodhead
Steven Woodhead
Eddy Freyne
Tom Govaerts
Patrick Angibaud
Brian Williams
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Astex Therapeutics Ltd
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Astex Therapeutics Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES09761801T 2008-06-13 2009-06-12 Derivados de la imidazopiridina como inhibidores de tirosina quinasas receptoras Active ES2735979T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6118408P 2008-06-13 2008-06-13
GBGB0810902.7A GB0810902D0 (en) 2008-06-13 2008-06-13 New compounds
PCT/EP2009/057318 WO2009150240A1 (en) 2008-06-13 2009-06-12 Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases

Publications (1)

Publication Number Publication Date
ES2735979T3 true ES2735979T3 (es) 2019-12-23

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ES09761801T Active ES2735979T3 (es) 2008-06-13 2009-06-12 Derivados de la imidazopiridina como inhibidores de tirosina quinasas receptoras

Country Status (21)

Country Link
US (1) US8796244B2 (OSRAM)
EP (1) EP2300465B1 (OSRAM)
JP (1) JP5596023B2 (OSRAM)
KR (1) KR101745730B1 (OSRAM)
CN (1) CN102137859B (OSRAM)
AU (1) AU2009256584B2 (OSRAM)
BR (1) BRPI0915084B8 (OSRAM)
CA (1) CA2727062A1 (OSRAM)
DK (1) DK2300465T3 (OSRAM)
ES (1) ES2735979T3 (OSRAM)
GB (1) GB0810902D0 (OSRAM)
HR (1) HRP20191027T1 (OSRAM)
HU (1) HUE045300T2 (OSRAM)
IL (1) IL209864A (OSRAM)
LT (1) LT2300465T (OSRAM)
MX (1) MX2010013743A (OSRAM)
NZ (1) NZ589781A (OSRAM)
RU (1) RU2518089C2 (OSRAM)
SI (1) SI2300465T1 (OSRAM)
WO (1) WO2009150240A1 (OSRAM)
ZA (1) ZA201008961B (OSRAM)

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