ES2665273T5 - Determinación no invasiva de metiloma del feto o tumor de plasma - Google Patents

Determinación no invasiva de metiloma del feto o tumor de plasma Download PDF

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Publication number
ES2665273T5
ES2665273T5 ES13838770T ES13838770T ES2665273T5 ES 2665273 T5 ES2665273 T5 ES 2665273T5 ES 13838770 T ES13838770 T ES 13838770T ES 13838770 T ES13838770 T ES 13838770T ES 2665273 T5 ES2665273 T5 ES 2665273T5
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methylation
plasma
dna
regions
cancer
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Spanish (es)
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ES2665273T3 (es
Inventor
Rossa Chiu
Kwan Chan
Yuk-Ming Lo
Miu Lun
Peiyong Jiang
Wai Chan
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Chinese University of Hong Kong CUHK
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Chinese University of Hong Kong CUHK
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Priority claimed from US13/842,209 external-priority patent/US9732390B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00—Reactions characterised by treatment of reaction samples
    • C12Q2523/10—Characterised by chemical treatment
    • C12Q2523/125—Bisulfite(s)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
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  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
ES13838770T 2012-09-20 2013-09-20 Determinación no invasiva de metiloma del feto o tumor de plasma Active ES2665273T5 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261703512P 2012-09-20 2012-09-20
US201261703512P 2012-09-20
US13/842,209 US9732390B2 (en) 2012-09-20 2013-03-15 Non-invasive determination of methylome of fetus or tumor from plasma
US201313842209 2013-03-15
US201361830571P 2013-06-03 2013-06-03
US201361830571P 2013-06-03
PCT/AU2013/001088 WO2014043763A1 (en) 2012-09-20 2013-09-20 Non-invasive determination of methylome of fetus or tumor from plasma

Publications (2)

Publication Number Publication Date
ES2665273T3 ES2665273T3 (es) 2018-04-25
ES2665273T5 true ES2665273T5 (es) 2023-10-02

Family

ID=50340462

Family Applications (4)

Application Number Title Priority Date Filing Date
ES13838770T Active ES2665273T5 (es) 2012-09-20 2013-09-20 Determinación no invasiva de metiloma del feto o tumor de plasma
ES19171630T Active ES2969567T3 (es) 2012-09-20 2013-09-20 Determinación no invasiva de metiloma de tumor de plasma
ES17202149T Active ES2862726T3 (es) 2012-09-20 2013-09-20 Determinación no invasiva de metiloma de tumor de plasma
ES22171427T Active ES2994426T3 (en) 2012-09-20 2013-09-20 Non-invasive determination of methylome of tumor from plasma

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES19171630T Active ES2969567T3 (es) 2012-09-20 2013-09-20 Determinación no invasiva de metiloma de tumor de plasma
ES17202149T Active ES2862726T3 (es) 2012-09-20 2013-09-20 Determinación no invasiva de metiloma de tumor de plasma
ES22171427T Active ES2994426T3 (en) 2012-09-20 2013-09-20 Non-invasive determination of methylome of tumor from plasma

Country Status (28)

Country Link
EP (6) EP2898100B9 (enExample)
JP (6) JP6317354B2 (enExample)
KR (5) KR102307424B1 (enExample)
CN (2) CN117757932A (enExample)
AU (5) AU2013317708C1 (enExample)
BR (3) BR112015006183B1 (enExample)
CA (2) CA3122779A1 (enExample)
CY (1) CY1124139T1 (enExample)
DK (4) DK3536807T3 (enExample)
EA (1) EA201500327A1 (enExample)
ES (4) ES2665273T5 (enExample)
FI (2) FI3536807T3 (enExample)
HR (3) HRP20240210T1 (enExample)
HU (3) HUE068129T2 (enExample)
IL (4) IL313451A (enExample)
LT (2) LT3354747T (enExample)
MX (1) MX360034B (enExample)
MY (2) MY187444A (enExample)
NZ (2) NZ706269A (enExample)
PH (2) PH12022552061A1 (enExample)
PL (4) PL3354747T3 (enExample)
PT (4) PT3536807T (enExample)
SG (2) SG11201501927VA (enExample)
SI (1) SI4056712T1 (enExample)
SM (1) SMT202100256T1 (enExample)
TW (4) TWI640634B (enExample)
WO (1) WO2014043763A1 (enExample)
ZA (1) ZA201501772B (enExample)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
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