ES2654670T3 - Compuestos útiles como inhibidores de la cinasa ATR y terapias de combinación de los mismos - Google Patents
Compuestos útiles como inhibidores de la cinasa ATR y terapias de combinación de los mismos Download PDFInfo
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- ES2654670T3 ES2654670T3 ES13728551.6T ES13728551T ES2654670T3 ES 2654670 T3 ES2654670 T3 ES 2654670T3 ES 13728551 T ES13728551 T ES 13728551T ES 2654670 T3 ES2654670 T3 ES 2654670T3
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US201261620717P | 2012-04-05 | 2012-04-05 | |
| US201261620717P | 2012-04-05 | ||
| PCT/US2013/035466 WO2013152298A1 (en) | 2012-04-05 | 2013-04-05 | Compounds useful as inhibitors of atr kinase and combination therapies thereof |
Publications (1)
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| ES2654670T3 true ES2654670T3 (es) | 2018-02-14 |
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| HK (1) | HK1205028A1 (OSRAM) |
| HR (1) | HRP20171915T1 (OSRAM) |
| HU (1) | HUE035253T2 (OSRAM) |
| IN (1) | IN2014KN02410A (OSRAM) |
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| MX (1) | MX358818B (OSRAM) |
| NO (1) | NO2885404T3 (OSRAM) |
| NZ (3) | NZ700580A (OSRAM) |
| PL (1) | PL2833973T3 (OSRAM) |
| PT (1) | PT2833973T (OSRAM) |
| RS (1) | RS56673B1 (OSRAM) |
| SI (1) | SI2833973T1 (OSRAM) |
| TW (2) | TW201740949A (OSRAM) |
| WO (1) | WO2013152298A1 (OSRAM) |
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- 2013-04-05 NZ NZ720511A patent/NZ720511A/en not_active IP Right Cessation
- 2013-04-05 JP JP2015504748A patent/JP2015515478A/ja not_active Withdrawn
- 2013-04-05 HU HUE13728551A patent/HUE035253T2/en unknown
- 2013-04-05 WO PCT/US2013/035466 patent/WO2013152298A1/en not_active Ceased
- 2013-04-05 EP EP17190136.6A patent/EP3311816A1/en not_active Withdrawn
- 2013-04-05 DK DK13728551.6T patent/DK2833973T3/en active
- 2013-04-05 CA CA2869309A patent/CA2869309C/en active Active
- 2013-04-05 SI SI201330879T patent/SI2833973T1/en unknown
- 2013-04-08 TW TW106107579A patent/TW201740949A/zh unknown
- 2013-04-08 TW TW102112405A patent/TWI644672B/zh not_active IP Right Cessation
- 2013-08-15 NO NO13829529A patent/NO2885404T3/no unknown
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2015
- 2015-08-03 US US14/816,432 patent/US10478430B2/en active Active
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2017
- 2017-07-25 JP JP2017143696A patent/JP6770490B2/ja not_active Expired - Fee Related
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2018
- 2018-01-24 AU AU2018200562A patent/AU2018200562A1/en not_active Abandoned
- 2018-06-08 JP JP2018110161A patent/JP2018150379A/ja not_active Withdrawn
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2019
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2020
- 2020-08-27 JP JP2020143455A patent/JP2020196748A/ja not_active Withdrawn
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2021
- 2021-08-03 US US17/444,318 patent/US20220233521A1/en not_active Abandoned
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