ES2642787T3 - Anticuerpos con actividad de citotoxicidad celular dependiente de anticuerpos mejorada, métodos para su producción y uso - Google Patents
Anticuerpos con actividad de citotoxicidad celular dependiente de anticuerpos mejorada, métodos para su producción y uso Download PDFInfo
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- ES2642787T3 ES2642787T3 ES11167183.0T ES11167183T ES2642787T3 ES 2642787 T3 ES2642787 T3 ES 2642787T3 ES 11167183 T ES11167183 T ES 11167183T ES 2642787 T3 ES2642787 T3 ES 2642787T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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| EP1945666B1 (en) * | 2005-10-21 | 2013-03-27 | GTC Biotherapeutics, Inc. | Antibodies with enhanced antibody-dependent cellular cytoxicity activity, methods of their production and use |
| US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
| WO2008030564A2 (en) * | 2006-09-08 | 2008-03-13 | Verenium Corporation | Aglycosylated antibodies and methods of making and using those antibodies |
| FR2915398B1 (fr) * | 2007-04-25 | 2012-12-28 | Lab Francais Du Fractionnement | "ensemble de moyens pour le traitement d'une pathologie maligne, d'une maladie auto-immune ou d'une maladie infectieuse" |
| EP1995309A1 (en) * | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
| US8647626B2 (en) | 2007-10-02 | 2014-02-11 | Avaxia Biologics, Incorporated | Compositions comprising TNF-specific antibodies for oral delivery |
| EP2244735A4 (en) * | 2007-10-02 | 2011-02-23 | Avaxia Biologics Inc | ANTIBODY THERAPY FOR USE IN THE DIGESTIVE TUBE |
| ES2336873B1 (es) * | 2007-11-07 | 2011-01-24 | Proyecto De Biomedicina Cima, S.L. | Composicion farmaceutica para el tratamiento de cancer. |
| US20110003338A1 (en) * | 2008-03-11 | 2011-01-06 | Robert Bayer | Antibodies with enhanced adcc function |
| US8591889B2 (en) | 2008-04-04 | 2013-11-26 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human monoclonal antibodies specific for CD22 |
| EP2279003A4 (en) * | 2008-05-01 | 2013-04-03 | Gtc Biotherapeutics Inc | ANTI-CD137 ANTIBODY AS A MEANS FOR THE TREATMENT OF INFLAMMATORY DISEASES |
| US8025879B2 (en) | 2008-09-26 | 2011-09-27 | Eureka Therapeutics, Inc. | Modified glycoproteins and uses thereof |
| WO2010042433A1 (en) * | 2008-10-06 | 2010-04-15 | Bristol-Myers Squibb Company | Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases |
| TWI409079B (zh) * | 2009-08-14 | 2013-09-21 | Roche Glycart Ag | 非典型岩藻醣化ｃｄ２０抗體與苯達莫斯汀（ｂｅｎｄａｍｕｓｔｉｎｅ）之組合療法 |
| HRP20240920T1 (hr) | 2009-10-26 | 2024-10-11 | F. Hoffmann - La Roche Ag | Postupak za proizvodnju glikoziliranog imunoglobulina |
| FR2962908A1 (fr) | 2010-07-20 | 2012-01-27 | Lfb Biotechnologies | Formulation d'anticorps anti-cd20 |
| WO2012090067A1 (en) | 2010-12-30 | 2012-07-05 | Lfb Biotechnologies | Glycols as pathogen inactivating agents |
| FR2976811A1 (fr) | 2011-06-22 | 2012-12-28 | Lfb Biotechnologies | Utilisation d'un anticorps anti-cd20 a haute adcc pour le traitement de la maladie de waldenstrom |
| KR20140062469A (ko) | 2011-07-20 | 2014-05-23 | 젭테온 인코포레이티드 | 폴리펩티드 분리 방법 |
| CN104168913A (zh) | 2011-08-10 | 2014-11-26 | 法国化学与生物科技实验室 | 高半乳糖基化抗体 |
| US20130302274A1 (en) * | 2011-11-25 | 2013-11-14 | Roche Glycart Ag | Combination therapy |
| US10059770B2 (en) | 2012-01-30 | 2018-08-28 | Dr. Reddy's Laboratories Limited | Process of modulating man5 and/or afucosylation content of a glycoprotein composition |
| US20150017687A1 (en) * | 2012-01-30 | 2015-01-15 | Dr. Reddy's Laboratories Limited | Method for obtaining a glycoprotein composition |
| CA2879763C (en) | 2012-08-03 | 2020-12-01 | Simon LOWRY | The use of antithrombin in extracorporeal membrane oxygenation |
| PL2925350T3 (pl) * | 2012-12-03 | 2019-07-31 | Bristol-Myers Squibb Company | Zwiększenie aktywności przeciwnowotworowej immunomodulacyjnych białek fuzyjnych fc |
| EP2931749B1 (fr) | 2012-12-17 | 2019-04-24 | Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme | Utilisation d'anticorps monoclonaux pour le traitement de l'inflammation et d'infections bacteriennes |
| WO2014140927A2 (en) | 2013-02-13 | 2014-09-18 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| KR20160003634A (ko) * | 2013-02-13 | 2016-01-11 | 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 | 고도로 갈락토실화된 항-her2 항체 및 이의 용도 |
| EP3594230A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| EP2956484B1 (en) | 2013-02-13 | 2018-11-14 | Laboratoire Français du Fractionnement et des Biotechnologies | Cetuximab with modified glycosylation and uses thereof |
| PL2991683T3 (pl) | 2013-05-02 | 2020-03-31 | Glykos Finland Oy | Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem |
| ES2793176T3 (es) | 2013-07-05 | 2020-11-13 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa | Matriz de cromografía de afinidad |
| FR3016633B1 (fr) | 2014-01-17 | 2018-04-13 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Immunoglobuline anti-toxine du charbon |
| US10780182B2 (en) | 2014-04-25 | 2020-09-22 | The Trustees Of The University Of Pennsylvania | Methods and compositions for treating metastatic breast cancer and other cancers in the brain |
| FR3025515B1 (fr) | 2014-09-05 | 2016-09-09 | Lab Francais Du Fractionnement | Procede de purification d'un anticorps monoclonal |
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| WO2007048077A2 (en) | 2007-04-26 |
| KR20140133958A (ko) | 2014-11-20 |
| KR20130089673A (ko) | 2013-08-12 |
| AU2006304886A1 (en) | 2007-04-26 |
| JP5328019B2 (ja) | 2013-10-30 |
| KR20080068089A (ko) | 2008-07-22 |
| KR101507027B1 (ko) | 2015-03-31 |
| EP2388273A1 (en) | 2011-11-23 |
| JP2009512694A (ja) | 2009-03-26 |
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| EP1945666A2 (en) | 2008-07-23 |
| WO2007048077A3 (en) | 2007-07-05 |
| DK2388273T3 (en) | 2017-10-09 |
| AU2006304886B2 (en) | 2012-04-12 |
| NZ568433A (en) | 2012-07-27 |
| EP2388272A1 (en) | 2011-11-23 |
| PL1945666T3 (pl) | 2013-09-30 |
| EP2388273B1 (en) | 2017-07-05 |
| CA2626542A1 (en) | 2007-04-26 |
| CN103435695A (zh) | 2013-12-11 |
| ES2417147T3 (es) | 2013-08-06 |
| JP2012250984A (ja) | 2012-12-20 |
| EP1945666B1 (en) | 2013-03-27 |
| CN101484470A (zh) | 2009-07-15 |
| CN101484470B (zh) | 2014-07-23 |
| US20080118501A1 (en) | 2008-05-22 |
| US20140046033A1 (en) | 2014-02-13 |
| CA2626542C (en) | 2018-07-03 |
| US20200255518A1 (en) | 2020-08-13 |
| IL218943A0 (en) | 2012-05-31 |
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