ES2575906T3 - Composiciones y métodos de producir metionina - Google Patents

Composiciones y métodos de producir metionina Download PDF

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Publication number
ES2575906T3
ES2575906T3 ES14173994.6T ES14173994T ES2575906T3 ES 2575906 T3 ES2575906 T3 ES 2575906T3 ES 14173994 T ES14173994 T ES 14173994T ES 2575906 T3 ES2575906 T3 ES 2575906T3
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Spain
Prior art keywords
compositions
methods
producing methionine
homoserine
succinyltransferase
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Active
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ES14173994.6T
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English (en)
Inventor
Brian Brazeau
Yong-Uk Shin
Hyewon Um
Jin-Sook Chang
Kwang Myung Cho
Young Wook Cho
Mervyn Desouza
Holly J. Jessen
So-Young Kim
Wei Niu
Fernando A. Sanchez-Riera
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CJ CheilJedang Corp
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CJ CheilJedang Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01046—Homoserine O-succinyltransferase (2.3.1.46)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Un polipéptido aislado con actividad homoserina O-succiniltransferasa, que muestra una sensibilidad reducida a inhibición por retroalimentación por L-metionina comparado con un polipéptido homoserina O- succiniltransferasa de tipo salvaje derivado de E. coli, y que comprende la secuencia de aminoácidos de SEQ ID NO: 8.
ES14173994.6T 2007-04-11 2007-04-11 Composiciones y métodos de producir metionina Active ES2575906T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/009146 WO2008127240A1 (en) 2007-04-11 2007-04-11 Compositions and methods of producing methionine

Publications (1)

Publication Number Publication Date
ES2575906T3 true ES2575906T3 (es) 2016-07-04

Family

ID=38800923

Family Applications (4)

Application Number Title Priority Date Filing Date
ES12165779.5T Active ES2534375T3 (es) 2007-04-11 2007-04-11 Composiciones y procedimientos de producción de metionina
ES07775377T Active ES2400261T3 (es) 2007-04-11 2007-04-11 Composiciones y procedimientos de producción de metionina
ES14173993.8T Active ES2575082T3 (es) 2007-04-11 2007-04-11 Composiciones y métodos de producción de metionina
ES14173994.6T Active ES2575906T3 (es) 2007-04-11 2007-04-11 Composiciones y métodos de producir metionina

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES12165779.5T Active ES2534375T3 (es) 2007-04-11 2007-04-11 Composiciones y procedimientos de producción de metionina
ES07775377T Active ES2400261T3 (es) 2007-04-11 2007-04-11 Composiciones y procedimientos de producción de metionina
ES14173993.8T Active ES2575082T3 (es) 2007-04-11 2007-04-11 Composiciones y métodos de producción de metionina

Country Status (8)

Country Link
US (3) US8551742B2 (es)
EP (4) EP2520645B1 (es)
JP (1) JP5497628B2 (es)
KR (1) KR101140906B1 (es)
CN (1) CN101688190B (es)
ES (4) ES2534375T3 (es)
PL (4) PL2808381T3 (es)
WO (1) WO2008127240A1 (es)

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KR100905381B1 (ko) 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
EP2520645B1 (en) 2007-04-11 2015-01-14 CJ CheilJedang Corporation Compositions and methods of producing methionine
KR100966324B1 (ko) * 2008-01-08 2010-06-28 씨제이제일제당 (주) 향상된 ｌ－쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ－쓰레오닌의 생산 방법
US7851180B2 (en) * 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US9005952B2 (en) 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US8283152B2 (en) * 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
US8609396B2 (en) * 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
RU2009136544A (ru) * 2009-10-05 2011-04-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ получения l-цистеина с использованием бактерии семейства enterobacteriaceae
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WO2012090021A1 (en) * 2010-12-30 2012-07-05 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
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PL3039153T3 (pl) * 2013-08-30 2019-02-28 Evonik Degussa Gmbh Mikroorganizm do wytwarzania metioniny o ulepszonej aktywności syntazy metioniny i wypływie metioniny
KR20160044038A (ko) * 2013-08-30 2016-04-22 메타볼릭 익스플로러 메티오닌 유출이 증진된 메티오닌 생산용 미생물
KR101555750B1 (ko) * 2013-10-23 2015-09-25 씨제이제일제당 (주) O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법
KR101565213B1 (ko) * 2013-10-23 2015-11-03 씨제이제일제당 (주) Ｏ-숙시닐호모세린 생산 미생물 및 이를 이용한 ｏ-숙시닐호모세린의 생산방법
KR101555749B1 (ko) * 2013-10-23 2015-09-25 씨제이제일제당 (주) O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법
KR101580785B1 (ko) * 2014-04-10 2015-12-29 씨제이제일제당 주식회사 O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법
KR20160111285A (ko) * 2015-03-16 2016-09-26 씨제이제일제당 (주) 사료 첨가제용 조성물 및 이를 포함하는 동물 사료 조성물
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CN106083992B (zh) * 2016-06-17 2019-08-20 四川松麒医药科技有限公司 一种肌肽衍生物的制备方法、产品及应用
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Also Published As

Publication number Publication date
EP2520645A2 (en) 2012-11-07
PL2808381T3 (pl) 2016-09-30
EP2132306A1 (en) 2009-12-16
EP2520645B1 (en) 2015-01-14
PL2808382T3 (pl) 2016-09-30
US9493801B2 (en) 2016-11-15
PL2520645T3 (pl) 2015-05-29
US20110183383A1 (en) 2011-07-28
EP2808382A1 (en) 2014-12-03
US20160024541A1 (en) 2016-01-28
EP2520645A3 (en) 2013-02-20
ES2534375T3 (es) 2015-04-22
US20130260424A1 (en) 2013-10-03
EP2132306B1 (en) 2012-12-19
EP2808382B1 (en) 2016-03-16
CN101688190B (zh) 2014-06-04
PL2132306T3 (pl) 2013-05-31
EP2808381B1 (en) 2016-03-09
US8551742B2 (en) 2013-10-08
JP5497628B2 (ja) 2014-05-21
JP2010523145A (ja) 2010-07-15
WO2008127240A1 (en) 2008-10-23
KR20100019417A (ko) 2010-02-18
US9150893B2 (en) 2015-10-06
CN101688190A (zh) 2010-03-31
ES2400261T3 (es) 2013-04-08
KR101140906B1 (ko) 2012-07-13
EP2808381A1 (en) 2014-12-03
ES2575082T3 (es) 2016-06-24

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