ES2524359T3 - Circovirus porcino, ácidos nucleicos, polipéptidos y vacunas - Google Patents
Circovirus porcino, ácidos nucleicos, polipéptidos y vacunas Download PDFInfo
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- ES2524359T3 ES2524359T3 ES05014998.8T ES05014998T ES2524359T3 ES 2524359 T3 ES2524359 T3 ES 2524359T3 ES 05014998 T ES05014998 T ES 05014998T ES 2524359 T3 ES2524359 T3 ES 2524359T3
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- 241000202347 Porcine circovirus Species 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 7
- 239000002773 nucleotide Substances 0.000 abstract 7
- 125000003729 nucleotide group Chemical group 0.000 abstract 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 4
- 230000000692 anti-sense effect Effects 0.000 abstract 4
- 241001673669 Porcine circovirus 2 Species 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
- 230000003313 weakening effect Effects 0.000 abstract 1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0321—Propionic acid bacteria
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0323—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin using only lactic acid bacteria, e.g. Pediococcus and Leuconostoc species; Bifidobacteria; Microbial starters in general
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A61K2039/552—Veterinary vaccine
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- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- C12N2710/00011—Details
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- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
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Abstract
Vector de expresión que comprende una secuencia de nucleótidos de un circovirus porcino de tipo II (PCV II) responsable del síndrome de debilitamiento generalizado posterior al destete (PMWS), en el que dicha secuencia de nucleótidos del vector comprende un marco abierto de lectura (MAL) del circovirus porcino de tipo II (PCV II), seleccionándose dicho marco abierto de lectura del grupo constituido por: - el marco abierto de lectura 4 (MAL 4) constituido por los nucleótidos 398 a 1342 de la hebra en sentido de la secuencia de referencia SEC ID Nº: 1, SEC ID Nº: 2, SEC ID Nº: 3, SEC ID Nº: 4 o SEC ID Nº: 6, - el marco abierto de lectura 13 (MAL 13) constituido por los nucleótidos 314 a 1377 de la hebra antisentido de la secuencia de referencia SEC ID Nº: 1 o SEC ID Nº: 2 o los nucleótidos 314 a 1381 de la hebra antisentido de la secuencia de referencia SEC ID Nº: 3, SEC ID Nº: 4 o SEC ID Nº: 6, - el marco abierto de lectura 7 (MAL 7) constituido por los nucleótidos 1018 a 704 de la hebra antisentido de la secuencia de referencia SEC ID Nº: 1, SEC ID Nº: 2, SEC ID Nº: 3, SEC ID Nº: 4 o SEC ID Nº: 6, y - el marco abierto de lectura 10 (MAL 10) constituido por los nucleótidos 912 a 733 de la hebra antisentido de la secuencia de referencia SEC ID Nº: 1, SEC ID Nº: 2, SEC ID Nº: 3, SEC ID Nº: 4 o SEC ID Nº: 6, expresando dicho vector de expresión in vitro o in vivo dicho marco abierto de lectura del circovirus porcino de tipo II.
Description
Claims (1)
-
imagen1 imagen2
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9712382A FR2769321B1 (fr) | 1997-10-03 | 1997-10-03 | Nouveaux circovirus porcins, vaccins et reactifs de diagnostics |
FR9712382 | 1997-10-03 | ||
FR9800873 | 1998-01-22 | ||
FR9800873A FR2769322B1 (fr) | 1997-10-03 | 1998-01-22 | Nouveaux circovirus porcins, vaccins et reactifs de diagnostic |
FR9803707A FR2776294B1 (fr) | 1998-03-20 | 1998-03-20 | Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic |
FR9803707 | 1998-03-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2524359T3 true ES2524359T3 (es) | 2014-12-05 |
Family
ID=27253376
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES05014998.8T Expired - Lifetime ES2524359T3 (es) | 1997-10-03 | 1998-10-01 | Circovirus porcino, ácidos nucleicos, polipéptidos y vacunas |
ES03016998T Expired - Lifetime ES2302885T3 (es) | 1997-10-03 | 1998-10-01 | Metodo de diagnostico in vitro de la infeccion por circovirus porcino de tipo ii y reactivos de diagnostico. |
ES02017134T Expired - Lifetime ES2246001T3 (es) | 1997-10-03 | 1998-10-01 | Circovirus porcino. |
ES98946547T Expired - Lifetime ES2203984T3 (es) | 1997-10-03 | 1998-10-01 | Vacunas a base de circovirus porcinos. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES03016998T Expired - Lifetime ES2302885T3 (es) | 1997-10-03 | 1998-10-01 | Metodo de diagnostico in vitro de la infeccion por circovirus porcino de tipo ii y reactivos de diagnostico. |
ES02017134T Expired - Lifetime ES2246001T3 (es) | 1997-10-03 | 1998-10-01 | Circovirus porcino. |
ES98946547T Expired - Lifetime ES2203984T3 (es) | 1997-10-03 | 1998-10-01 | Vacunas a base de circovirus porcinos. |
Country Status (21)
Country | Link |
---|---|
US (1) | US6368601B1 (es) |
EP (4) | EP1281760B9 (es) |
JP (5) | JP5008218B2 (es) |
KR (4) | KR100854615B1 (es) |
CN (2) | CN100584948C (es) |
AT (3) | ATE245191T1 (es) |
AU (1) | AU756554C (es) |
BR (1) | BR9812845B1 (es) |
CA (1) | CA2305623C (es) |
CY (3) | CY1110359T1 (es) |
DE (7) | DE122005000009I1 (es) |
DK (4) | DK1281760T5 (es) |
ES (4) | ES2524359T3 (es) |
FR (1) | FR05C0021I2 (es) |
HK (1) | HK1095161A1 (es) |
HU (2) | HU230340B1 (es) |
NL (1) | NL300326I2 (es) |
PL (1) | PL198506B1 (es) |
PT (4) | PT1386617E (es) |
UA (1) | UA78180C2 (es) |
WO (1) | WO1999018214A1 (es) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060029617A1 (en) * | 1997-10-03 | 2006-02-09 | Charreyre Catherine E | Porcine circovirus and Helicobacter combination vaccines and methods of use |
US6391314B1 (en) * | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
US7192594B2 (en) * | 1997-10-03 | 2007-03-20 | Merial Limited | Postweaning multisystemic wasting syndrome and porcine circovirus from pigs |
US7211379B2 (en) * | 1997-10-03 | 2007-05-01 | Merial Sas | Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2 |
US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
FR2781159B1 (fr) * | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
FR2772047B1 (fr) * | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
US20040062775A1 (en) * | 1997-12-05 | 2004-04-01 | Agence Francaise De Securite Sanitaire Des Aliments | Circovirus sequences associated with piglet weight loss disease (PWD) |
PT2363488E (pt) * | 1997-12-11 | 2015-01-13 | Univ Belfast | Síndrome multi-sistémica do definhamento pós-desmame de porcos |
EP1816200B1 (en) * | 1997-12-11 | 2016-03-09 | Merial | Postweaning multisystemic wasting syndrome virus for pigs |
US6497883B1 (en) * | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
US6943152B1 (en) * | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
ES2170622B1 (es) * | 1999-12-03 | 2004-05-16 | Consejo Superior De Investigaciones Cientificas | Clones y vectores infectivos derivados de coronavirus y sus aplicaciones. |
WO2001096377A2 (en) * | 2000-06-15 | 2001-12-20 | Purdue Research Foundation | Vaccine for congenital tremors in pigs |
US7018638B2 (en) * | 2000-12-19 | 2006-03-28 | Wyeth | Mycoplasma hyopneumoniae bacterin vaccine |
EP1379671B1 (en) * | 2001-03-27 | 2009-05-06 | University of Saskatchewan | Methods to culture circovirus |
CA2454397A1 (en) | 2001-07-20 | 2003-06-05 | The University Of Georgia Research Foundation, Inc. | Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the cns |
US7279166B2 (en) | 2001-12-12 | 2007-10-09 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
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EA011578B1 (ru) * | 2002-08-26 | 2009-04-28 | Пфайзер Продактс Инк. | Иммуногенная композиция для защиты крупного рогатого скота от инфекций респираторной и репродуктивной систем и ее применение |
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